FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4315754117> ?p ?o ?g. }

• W4315754117 endingPage "180" @default.
• W4315754117 startingPage "159" @default.
• W4315754117 abstract "Malignancies of the peritoneal cavity are associated with a dismal prognosis. Systemic chemotherapy is the gold standard for patients with unresectable peritoneal disease, but its intraperitoneal effect is hampered by the peritoneal-plasma barrier. Intraperitoneal chemotherapy, which is administered repeatedly into the peritoneal cavity through a peritoneal implanted port, could provide a novel treatment modality for this patient population. This review provides a systematic overview of intraperitoneal used drugs, the performed clinical studies so far, and the complications of the peritoneal implemental ports. Several anticancer drugs have been studied for intraperitoneal application, with the taxanes paclitaxel and docetaxel as the most commonly used drug. Repeated intraperitoneal chemotherapy, mostly in combination with systemic chemotherapy, has shown promising results in Phase I and Phase II studies for several tumor types, such as gastric cancer, ovarian cancer, colorectal cancer, and pancreatic cancer. Two Phase III studies for intraperitoneal chemotherapy in gastric cancer have been performed so far, but the results regarding the superiority over standard systemic chemotherapy alone, are contradictory. Pressurized intraperitoneal administration, known as PIPAC, is an alternative way of administering intraperitoneal chemotherapy, and the first prospective studies have shown a tolerable safety profile. Although intraperitoneal chemotherapy might be a standard treatment option for patients with unresectable peritoneal disease, more Phase II and Phase III studies focusing on tolerability profiles, survival rates, and quality of life are warranted in order to establish optimal treatment schedules and to establish a potential role for intraperitoneal chemotherapy in the approach to unresectable peritoneal disease." @default.
• W4315754117 created "2023-01-13" @default.
• W4315754117 creator A5008685422 @default.
• W4315754117 creator A5013432555 @default.
• W4315754117 creator A5018004001 @default.
• W4315754117 creator A5021822394 @default.
• W4315754117 creator A5021833630 @default.
• W4315754117 creator A5029196683 @default.
• W4315754117 creator A5033117942 @default.
• W4315754117 creator A5048678810 @default.
• W4315754117 creator A5050202217 @default.
• W4315754117 creator A5053269718 @default.
• W4315754117 creator A5063039968 @default.
• W4315754117 creator A5064280092 @default.
• W4315754117 creator A5065885053 @default.
• W4315754117 creator A5071697710 @default.
• W4315754117 creator A5074174053 @default.
• W4315754117 creator A5074957985 @default.
• W4315754117 date "2023-01-12" @default.
• W4315754117 modified "2023-10-13" @default.
• W4315754117 title "Intraperitoneal Chemotherapy for Unresectable Peritoneal Surface Malignancies" @default.
• W4315754117 cites W1578654420 @default.
• W4315754117 cites W1837164844 @default.
• W4315754117 cites W1871865048 @default.
• W4315754117 cites W1927044883 @default.
• W4315754117 cites W1964089649 @default.
• W4315754117 cites W1964172790 @default.
• W4315754117 cites W1968871067 @default.
• W4315754117 cites W1971046656 @default.
• W4315754117 cites W1976837208 @default.
• W4315754117 cites W1983823631 @default.
• W4315754117 cites W1988943147 @default.
• W4315754117 cites W1992415959 @default.
• W4315754117 cites W1999905581 @default.
• W4315754117 cites W2004770693 @default.
• W4315754117 cites W2013887280 @default.
• W4315754117 cites W2020359125 @default.
• W4315754117 cites W2021689695 @default.
• W4315754117 cites W2022324307 @default.
• W4315754117 cites W2028422168 @default.
• W4315754117 cites W2031744300 @default.
• W4315754117 cites W2033077877 @default.
• W4315754117 cites W2034903741 @default.
• W4315754117 cites W2036832628 @default.
• W4315754117 cites W2042633087 @default.
• W4315754117 cites W2044221999 @default.
• W4315754117 cites W2053529558 @default.
• W4315754117 cites W2057831335 @default.
• W4315754117 cites W2060590865 @default.
• W4315754117 cites W2065603549 @default.
• W4315754117 cites W2068572207 @default.
• W4315754117 cites W2069066070 @default.
• W4315754117 cites W2088514490 @default.
• W4315754117 cites W2094282118 @default.
• W4315754117 cites W2100095673 @default.
• W4315754117 cites W2103950307 @default.
• W4315754117 cites W2104186733 @default.
• W4315754117 cites W2122700913 @default.
• W4315754117 cites W2126235955 @default.
• W4315754117 cites W2133778309 @default.
• W4315754117 cites W2140754798 @default.
• W4315754117 cites W2141758658 @default.
• W4315754117 cites W2142114138 @default.
• W4315754117 cites W2146898191 @default.
• W4315754117 cites W2147485225 @default.
• W4315754117 cites W2149861058 @default.
• W4315754117 cites W2157595683 @default.
• W4315754117 cites W2159140139 @default.
• W4315754117 cites W2163719825 @default.
• W4315754117 cites W2163753908 @default.
• W4315754117 cites W2256443711 @default.
• W4315754117 cites W2298579443 @default.
• W4315754117 cites W2334906808 @default.
• W4315754117 cites W2335368384 @default.
• W4315754117 cites W2475170675 @default.
• W4315754117 cites W2484582657 @default.
• W4315754117 cites W2516297778 @default.
• W4315754117 cites W2516882085 @default.
• W4315754117 cites W2521892896 @default.
• W4315754117 cites W2531203326 @default.
• W4315754117 cites W2547914193 @default.
• W4315754117 cites W2567310682 @default.
• W4315754117 cites W2596745312 @default.
• W4315754117 cites W2610585226 @default.
• W4315754117 cites W2616818508 @default.
• W4315754117 cites W2760472470 @default.
• W4315754117 cites W2766777872 @default.
• W4315754117 cites W2769284793 @default.
• W4315754117 cites W2774045934 @default.
• W4315754117 cites W2784597821 @default.
• W4315754117 cites W2790768119 @default.
• W4315754117 cites W2791851394 @default.
• W4315754117 cites W2801279586 @default.
• W4315754117 cites W2806804067 @default.
• W4315754117 cites W2885546665 @default.
• W4315754117 cites W2898330049 @default.
• W4315754117 cites W2899275142 @default.
• W4315754117 cites W2905254350 @default.

• next