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• W4315754310 abstract "Abstract A total of 240 28-d-old male goslings were used to investigate the effects of cottonseed meal (CSM) on performance, gossypol residue, liver function, lipid metabolism, and cecal microbiota. All birds were randomly allotted into five groups (eight goslings/replicate, six replicates/group) and subjected to a 35-d experiment. Five isonitrogenous and isoenergetic diets were formulated to produce diets in which 0% (control), 25% (CSM25), 50% (CSM50), 75% (CSM75), and 100% (CSM100) of protein from soybean meal was replaced by protein from CSM. The free gossypol contents in the five diets were 0, 44, 92, 135, and 183 mg/kg, respectively. Dietary CSM did not affect the growth performance from 29 to 63 d and carcass traits at 63 d (P &gt; 0.05). Liver gossypol residues were influenced (P &lt; 0.05) by dietary CSM and increased linearly (P &lt; 0.05) and quadratically (P &lt; 0.05) as dietary CSM increased. The malondialdehyde content of the liver was lower in the CSM100 group than in the other groups (P &lt; 0.05). Serum triglyceride and low-density lipoprotein cholesterol were influenced (P &lt; 0.05) by dietary CSM and increased linearly (P &lt; 0.05) with increasing dietary CSM. Dietary CSM altered (P &lt; 0.05) the composition of some fatty acids in the liver and breast muscle. The concentration of linolenic acid and Σn-3 polyunsaturated fatty acid (PUFA) in the liver and breast muscle decreased linearly, but the Σn-6/Σn-3 PUFA ratio increased linearly with increasing dietary CSM (P &lt; 0.05). Dietary CSM affected (P &lt; 0.05) the hepatic gene expression of fatty acid synthase (FAS), acetyl-CoA carboxylase (ACC), and apolipoprotein B (ApoB). As the dietary CSM concentration increased, the hepatic gene expression of FAS increased linearly (P &lt; 0.05) and quadratically (P &lt; 0.05), but the hepatic gene expression of ACC and ApoB increased linearly (P &lt; 0.05). The CSM diet decreased the relative abundance of the Bacteroidota and Bacteroides (P &lt; 0.05), and the CSM50 diet increased the relative abundance of the Firmicutes and Colidextribacter (P &lt; 0.05) compared to the control group. Overall, these results show that dietary CSM has no adverse effects on the performance of goslings from 29 to 63 d. However, CSM affected organismal lipid metabolism, reduced products’ edible value, and adaptively altered cecum microbiota." @default.
• W4315754310 created "2023-01-13" @default.
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• W4315754310 date "2023-01-01" @default.
• W4315754310 modified "2023-09-27" @default.
• W4315754310 title "Effects of cottonseed meal on performance, gossypol residue, liver function, lipid metabolism, and cecal microbiota in geese" @default.
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• W4315754310 doi "https://doi.org/10.1093/jas/skad020" @default.
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