Matches in SemOpenAlex for { <https://semopenalex.org/work/W4315778145> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W4315778145 endingPage "284" @default.
- W4315778145 startingPage "273" @default.
- W4315778145 abstract "Mast cells protect a host from invasion by infectious agents and environmental allergens through activation of innate and adaptive immune receptors, their excessive activation being tightly regulated by inhibitory receptors, such as leukocyte immunoglobulin-like receptor (LILR)B4 (gp49B in mice). However, the regulatory mechanism of LILRB4/gp49B expressed on mast cells remains to be clarified in relation to their recently identified ligand, fibronectin (FN), a direct activator of integrins and an indirect stimulator of high-affinity Fc receptor for IgE (FcεRI). Confocal microscopic analysis suggested that gp49B is spatially close to integrin β1 on non-adhered bone marrow-derived mast cells (BMMCs). Their spatial relatedness increases further at robust focal adhesion sites on cells adhering to immobilized FN. However, the confocal fluorescence signal of the α subunit of FcεRI was found to be correlated to neither gp49B nor integrin β1 on non-adherent and adherent BMMCs. Stimulation of FcεRI with an immobilized antigen caused FcεRIα signals to accumulate in an inside area surrounded by robust focal adhesion with a concomitant slight increase in the signal correlation of FcεRIα and integrin β1, accompanied by a less significant increase of the FcεRIα and gp49 correlation. Thus, activating and inhibitory FN receptors integrin and gp49B, respectively, were co-localized via FN at robust focal adhesion sites on BMMCs, while FcεRI was not close to gp49B spatially." @default.
- W4315778145 created "2023-01-13" @default.
- W4315778145 creator A5005613954 @default.
- W4315778145 creator A5005762940 @default.
- W4315778145 creator A5030419896 @default.
- W4315778145 creator A5069965100 @default.
- W4315778145 creator A5076600186 @default.
- W4315778145 date "2023-01-01" @default.
- W4315778145 modified "2023-10-01" @default.
- W4315778145 title "LILRB4/gp49B Co-Localizes with Integrin via Fibronectin at Focal Adhesion Sites on Mast Cells" @default.
- W4315778145 cites W135611249 @default.
- W4315778145 cites W1481392666 @default.
- W4315778145 cites W14894812 @default.
- W4315778145 cites W1521066181 @default.
- W4315778145 cites W1638075714 @default.
- W4315778145 cites W1841307713 @default.
- W4315778145 cites W1969075833 @default.
- W4315778145 cites W1970483666 @default.
- W4315778145 cites W1989093331 @default.
- W4315778145 cites W1993607801 @default.
- W4315778145 cites W1997153240 @default.
- W4315778145 cites W2032248432 @default.
- W4315778145 cites W2033330205 @default.
- W4315778145 cites W2063559185 @default.
- W4315778145 cites W2073553590 @default.
- W4315778145 cites W2098724589 @default.
- W4315778145 cites W2100895205 @default.
- W4315778145 cites W2164808771 @default.
- W4315778145 cites W2171376237 @default.
- W4315778145 cites W2530376622 @default.
- W4315778145 cites W2780966665 @default.
- W4315778145 cites W2896256743 @default.
- W4315778145 cites W2913308488 @default.
- W4315778145 cites W3162381463 @default.
- W4315778145 cites W3171434525 @default.
- W4315778145 cites W3189920043 @default.
- W4315778145 cites W3193307873 @default.
- W4315778145 cites W4226175296 @default.
- W4315778145 cites W4282919439 @default.
- W4315778145 cites W4282920215 @default.
- W4315778145 doi "https://doi.org/10.1620/tjem.2023.j001" @default.
- W4315778145 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36642505" @default.
- W4315778145 hasPublicationYear "2023" @default.
- W4315778145 type Work @default.
- W4315778145 citedByCount "0" @default.
- W4315778145 crossrefType "journal-article" @default.
- W4315778145 hasAuthorship W4315778145A5005613954 @default.
- W4315778145 hasAuthorship W4315778145A5005762940 @default.
- W4315778145 hasAuthorship W4315778145A5030419896 @default.
- W4315778145 hasAuthorship W4315778145A5069965100 @default.
- W4315778145 hasAuthorship W4315778145A5076600186 @default.
- W4315778145 hasBestOaLocation W43157781451 @default.
- W4315778145 hasConcept C151166631 @default.
- W4315778145 hasConcept C153911025 @default.
- W4315778145 hasConcept C170493617 @default.
- W4315778145 hasConcept C185592680 @default.
- W4315778145 hasConcept C189165786 @default.
- W4315778145 hasConcept C195687474 @default.
- W4315778145 hasConcept C49802076 @default.
- W4315778145 hasConcept C55493867 @default.
- W4315778145 hasConcept C62478195 @default.
- W4315778145 hasConcept C86492073 @default.
- W4315778145 hasConcept C86803240 @default.
- W4315778145 hasConcept C95444343 @default.
- W4315778145 hasConceptScore W4315778145C151166631 @default.
- W4315778145 hasConceptScore W4315778145C153911025 @default.
- W4315778145 hasConceptScore W4315778145C170493617 @default.
- W4315778145 hasConceptScore W4315778145C185592680 @default.
- W4315778145 hasConceptScore W4315778145C189165786 @default.
- W4315778145 hasConceptScore W4315778145C195687474 @default.
- W4315778145 hasConceptScore W4315778145C49802076 @default.
- W4315778145 hasConceptScore W4315778145C55493867 @default.
- W4315778145 hasConceptScore W4315778145C62478195 @default.
- W4315778145 hasConceptScore W4315778145C86492073 @default.
- W4315778145 hasConceptScore W4315778145C86803240 @default.
- W4315778145 hasConceptScore W4315778145C95444343 @default.
- W4315778145 hasIssue "4" @default.
- W4315778145 hasLocation W43157781451 @default.
- W4315778145 hasLocation W43157781452 @default.
- W4315778145 hasOpenAccess W4315778145 @default.
- W4315778145 hasPrimaryLocation W43157781451 @default.
- W4315778145 hasRelatedWork W192658524 @default.
- W4315778145 hasRelatedWork W1994314084 @default.
- W4315778145 hasRelatedWork W2002515131 @default.
- W4315778145 hasRelatedWork W2057698056 @default.
- W4315778145 hasRelatedWork W2085039514 @default.
- W4315778145 hasRelatedWork W2117027159 @default.
- W4315778145 hasRelatedWork W2149067219 @default.
- W4315778145 hasRelatedWork W2389792790 @default.
- W4315778145 hasRelatedWork W4205126071 @default.
- W4315778145 hasRelatedWork W4244048000 @default.
- W4315778145 hasVolume "259" @default.
- W4315778145 isParatext "false" @default.
- W4315778145 isRetracted "false" @default.
- W4315778145 workType "article" @default.