Matches in SemOpenAlex for { <https://semopenalex.org/work/W4315784808> ?p ?o ?g. }
- W4315784808 abstract "Abstract Increasing drug loading remains a critical challenge in the development and translation of nanomedicine. High drug‐loading nanoparticles have demonstrated unique advantages such as less carrier material used, better‐controlled drug release, and improved efficacy and safety. Herein, we report a simple and efficient salt concentration screening method for making polymer nanoparticles with exceptionally high drug loading (up to 66.5 wt%) based on phase separation‐induced nanoprecipitation. Upon addition of salt, phase separation occurs in a miscible solvent‐water solution delaying the precipitation time of drugs and polymers to different extents, facilitating their co‐precipitation thus the formation of high drug‐loading nanoparticles with high encapsulation efficiency (>90%) and excellent stability (>1 month). This technology is versatile and easy to be adapted to various hydrophobic drugs, different polymers, and solvents. This salt‐induced nanoprecipitation strategy offers a novel approach to fabricating polymer nanoparticles with tunable drug loading, and opens great potentials for future nanomedicines." @default.
- W4315784808 created "2023-01-13" @default.
- W4315784808 creator A5003065832 @default.
- W4315784808 creator A5007335297 @default.
- W4315784808 creator A5019914168 @default.
- W4315784808 creator A5029851581 @default.
- W4315784808 creator A5037275754 @default.
- W4315784808 creator A5038905661 @default.
- W4315784808 creator A5058021944 @default.
- W4315784808 creator A5084461656 @default.
- W4315784808 creator A5086835948 @default.
- W4315784808 date "2023-01-12" @default.
- W4315784808 modified "2023-10-18" @default.
- W4315784808 title "Phase separation‐induced nanoprecipitation for making polymer nanoparticles with high drug loading" @default.
- W4315784808 cites W109788472 @default.
- W4315784808 cites W1869516088 @default.
- W4315784808 cites W1990720548 @default.
- W4315784808 cites W2004186868 @default.
- W4315784808 cites W2024696677 @default.
- W4315784808 cites W2032916735 @default.
- W4315784808 cites W2035263589 @default.
- W4315784808 cites W2061999464 @default.
- W4315784808 cites W2072266745 @default.
- W4315784808 cites W2081250149 @default.
- W4315784808 cites W2089745755 @default.
- W4315784808 cites W2315315241 @default.
- W4315784808 cites W2321827248 @default.
- W4315784808 cites W2344949123 @default.
- W4315784808 cites W2345916941 @default.
- W4315784808 cites W2397946201 @default.
- W4315784808 cites W2465228760 @default.
- W4315784808 cites W2596707465 @default.
- W4315784808 cites W2618974892 @default.
- W4315784808 cites W2742287127 @default.
- W4315784808 cites W2789367943 @default.
- W4315784808 cites W2817972095 @default.
- W4315784808 cites W2971165342 @default.
- W4315784808 cites W3023959051 @default.
- W4315784808 cites W3046279415 @default.
- W4315784808 cites W3048450008 @default.
- W4315784808 cites W3107820863 @default.
- W4315784808 cites W3128424738 @default.
- W4315784808 cites W3173397475 @default.
- W4315784808 cites W4223581013 @default.
- W4315784808 cites W4230989546 @default.
- W4315784808 cites W4255290184 @default.
- W4315784808 doi "https://doi.org/10.1002/agt2.314" @default.
- W4315784808 hasPublicationYear "2023" @default.
- W4315784808 type Work @default.
- W4315784808 citedByCount "1" @default.
- W4315784808 countsByYear W43157848082023 @default.
- W4315784808 crossrefType "journal-article" @default.
- W4315784808 hasAuthorship W4315784808A5003065832 @default.
- W4315784808 hasAuthorship W4315784808A5007335297 @default.
- W4315784808 hasAuthorship W4315784808A5019914168 @default.
- W4315784808 hasAuthorship W4315784808A5029851581 @default.
- W4315784808 hasAuthorship W4315784808A5037275754 @default.
- W4315784808 hasAuthorship W4315784808A5038905661 @default.
- W4315784808 hasAuthorship W4315784808A5058021944 @default.
- W4315784808 hasAuthorship W4315784808A5084461656 @default.
- W4315784808 hasAuthorship W4315784808A5086835948 @default.
- W4315784808 hasBestOaLocation W43157848081 @default.
- W4315784808 hasConcept C107054158 @default.
- W4315784808 hasConcept C121332964 @default.
- W4315784808 hasConcept C127413603 @default.
- W4315784808 hasConcept C15083742 @default.
- W4315784808 hasConcept C153294291 @default.
- W4315784808 hasConcept C155672457 @default.
- W4315784808 hasConcept C159985019 @default.
- W4315784808 hasConcept C171250308 @default.
- W4315784808 hasConcept C178790620 @default.
- W4315784808 hasConcept C185592680 @default.
- W4315784808 hasConcept C192562407 @default.
- W4315784808 hasConcept C2776371256 @default.
- W4315784808 hasConcept C2779820397 @default.
- W4315784808 hasConcept C2780035454 @default.
- W4315784808 hasConcept C2780471494 @default.
- W4315784808 hasConcept C42360764 @default.
- W4315784808 hasConcept C44280652 @default.
- W4315784808 hasConcept C521977710 @default.
- W4315784808 hasConcept C71924100 @default.
- W4315784808 hasConcept C98274493 @default.
- W4315784808 hasConceptScore W4315784808C107054158 @default.
- W4315784808 hasConceptScore W4315784808C121332964 @default.
- W4315784808 hasConceptScore W4315784808C127413603 @default.
- W4315784808 hasConceptScore W4315784808C15083742 @default.
- W4315784808 hasConceptScore W4315784808C153294291 @default.
- W4315784808 hasConceptScore W4315784808C155672457 @default.
- W4315784808 hasConceptScore W4315784808C159985019 @default.
- W4315784808 hasConceptScore W4315784808C171250308 @default.
- W4315784808 hasConceptScore W4315784808C178790620 @default.
- W4315784808 hasConceptScore W4315784808C185592680 @default.
- W4315784808 hasConceptScore W4315784808C192562407 @default.
- W4315784808 hasConceptScore W4315784808C2776371256 @default.
- W4315784808 hasConceptScore W4315784808C2779820397 @default.
- W4315784808 hasConceptScore W4315784808C2780035454 @default.
- W4315784808 hasConceptScore W4315784808C2780471494 @default.
- W4315784808 hasConceptScore W4315784808C42360764 @default.
- W4315784808 hasConceptScore W4315784808C44280652 @default.
- W4315784808 hasConceptScore W4315784808C521977710 @default.