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- W4315864587 endingPage "100075" @default.
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- W4315864587 abstract "Coenzyme A (CoA) is an essential cofactor in all living cells which plays critical role in cellular metabolism, the regulation of gene expression and the biosynthesis of major cellular constituents. Recently, CoA was found to function as a major antioxidant in both prokaryotic and eukaryotic cells. This unconventional function of CoA is mediated by a novel post-translational modification, termed protein CoAlation. This review will highlight the history of this discovery, current knowledge, and future directions on studying molecular mechanisms of protein CoAlation and whether the antioxidant function of CoA is associated with pathologies, such as neurodegeneration and cancer." @default.
- W4315864587 created "2023-01-13" @default.
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- W4315864587 date "2023-01-01" @default.
- W4315864587 modified "2023-10-17" @default.
- W4315864587 title "Discovery and functional characterisation of protein CoAlation and the antioxidant function of coenzyme A" @default.
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- W4315864587 doi "https://doi.org/10.1016/j.bbadva.2023.100075" @default.
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