FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4315866019> ?p ?o ?g. }

• W4315866019 abstract "Fibromyalgia (FM) is associated with sympathetically dominant dysautonomia, but the connection between dysautonomia and FM symptoms is unclear. Dysautonomia can be analysed with heart rate variability (HRV) and it has been proposed that FM patients comprise subgroups with differing profiles of symptom severity. In our study, 51 female FM patients aged 18 to 65 years and 31 age-matched healthy female controls followed a 20-min protocol of alternating relaxation and cognitive stress (mental arithmetic). Heart rates and electrocardiograms were registered. The HRV measures of heart rate (HR), mean interval between heart beats (RRmean), root mean squared interval differences of successive beats (RMSSD), and the standard deviation of intervals between normal heart beats (SDNN) were analysed with generalized linear modelling. Features in HRV reactivity which differed between FM patients and controls were used to cluster the FM patients and cluster characteristics were analysed. FM patients had higher baseline HR (72.3 [SD 12.7] vs 64.5 [7.80], p < 0.001) and lower RRmean (0.844 [0.134] vs 0.934 [0.118], p = 0.002), compared with controls. They also reacted to repeated cognitive stress with an attenuated rise in HR (- 4.41 [95% CI - 7.88 to - 0.93], p = 0.013) and attenuated decrease of RRmean (0.06 [95 CI 0.03 to 0.09], p < 0.001), compared with controls. Clustering of FM patients by HRV reactivity resulted in three clusters characterised by (1) normal levels of HRV and HRV reactivity with low levels of depressive mood and anxiety, (2) reduced levels of HRV and impaired HRV reactivity with increased levels of depressive mood and high levels of anxiety, and (3) lowest HRV and most impaired HRV reactivity with the highest scores for depressive mood and anxiety. Our results show that FM patients have lower HRV than healthy controls and their autonomous reactions to cognitive stress are attenuated. Dysautonomia in FM associates with mood disturbance. Trial registration ClinicalTrials.gov (NCT03300635). Registered October 3 2017-Retrospectively registered, https://clinicaltrials.gov/ct2/show/NCT03300635 ." @default.
• W4315866019 created "2023-01-13" @default.
• W4315866019 creator A5016378638 @default.
• W4315866019 creator A5055611659 @default.
• W4315866019 creator A5062557070 @default.
• W4315866019 creator A5076070835 @default.
• W4315866019 date "2023-01-13" @default.
• W4315866019 modified "2023-10-18" @default.
• W4315866019 title "Heart rate variability responses to cognitive stress in fibromyalgia are characterised by inadequate autonomous system stress responses: a clinical trial" @default.
• W4315866019 cites W1859643696 @default.
• W4315866019 cites W1989052624 @default.
• W4315866019 cites W1996299251 @default.
• W4315866019 cites W2002816565 @default.
• W4315866019 cites W2014777834 @default.
• W4315866019 cites W2064816942 @default.
• W4315866019 cites W2071429898 @default.
• W4315866019 cites W2076089275 @default.
• W4315866019 cites W2089010517 @default.
• W4315866019 cites W2093131181 @default.
• W4315866019 cites W2103714534 @default.
• W4315866019 cites W2114695600 @default.
• W4315866019 cites W2253364553 @default.
• W4315866019 cites W2336628460 @default.
• W4315866019 cites W2346744058 @default.
• W4315866019 cites W2411122968 @default.
• W4315866019 cites W2414144199 @default.
• W4315866019 cites W2513400162 @default.
• W4315866019 cites W2592663909 @default.
• W4315866019 cites W2759190050 @default.
• W4315866019 cites W2887862731 @default.
• W4315866019 cites W2917146357 @default.
• W4315866019 cites W2943137155 @default.
• W4315866019 cites W2949750735 @default.
• W4315866019 cites W2953639947 @default.
• W4315866019 cites W2965204101 @default.
• W4315866019 cites W2972803473 @default.
• W4315866019 cites W3006602012 @default.
• W4315866019 cites W3091896746 @default.
• W4315866019 cites W3122095233 @default.
• W4315866019 cites W3131503037 @default.
• W4315866019 doi "https://doi.org/10.1038/s41598-023-27581-9" @default.
• W4315866019 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36639565" @default.
• W4315866019 hasPublicationYear "2023" @default.
• W4315866019 type Work @default.
• W4315866019 citedByCount "1" @default.
• W4315866019 countsByYear W43158660192023 @default.
• W4315866019 crossrefType "journal-article" @default.
• W4315866019 hasAuthorship W4315866019A5016378638 @default.
• W4315866019 hasAuthorship W4315866019A5055611659 @default.
• W4315866019 hasAuthorship W4315866019A5062557070 @default.
• W4315866019 hasAuthorship W4315866019A5076070835 @default.
• W4315866019 hasBestOaLocation W43158660191 @default.
• W4315866019 hasConcept C10928738 @default.
• W4315866019 hasConcept C118552586 @default.
• W4315866019 hasConcept C126322002 @default.
• W4315866019 hasConcept C164705383 @default.
• W4315866019 hasConcept C18325288 @default.
• W4315866019 hasConcept C2777372248 @default.
• W4315866019 hasConcept C2777831278 @default.
• W4315866019 hasConcept C2777953023 @default.
• W4315866019 hasConcept C2779134260 @default.
• W4315866019 hasConcept C2779543035 @default.
• W4315866019 hasConcept C2780733359 @default.
• W4315866019 hasConcept C558461103 @default.
• W4315866019 hasConcept C71635504 @default.
• W4315866019 hasConcept C71924100 @default.
• W4315866019 hasConcept C84393581 @default.
• W4315866019 hasConceptScore W4315866019C10928738 @default.
• W4315866019 hasConceptScore W4315866019C118552586 @default.
• W4315866019 hasConceptScore W4315866019C126322002 @default.
• W4315866019 hasConceptScore W4315866019C164705383 @default.
• W4315866019 hasConceptScore W4315866019C18325288 @default.
• W4315866019 hasConceptScore W4315866019C2777372248 @default.
• W4315866019 hasConceptScore W4315866019C2777831278 @default.
• W4315866019 hasConceptScore W4315866019C2777953023 @default.
• W4315866019 hasConceptScore W4315866019C2779134260 @default.
• W4315866019 hasConceptScore W4315866019C2779543035 @default.
• W4315866019 hasConceptScore W4315866019C2780733359 @default.
• W4315866019 hasConceptScore W4315866019C558461103 @default.
• W4315866019 hasConceptScore W4315866019C71635504 @default.
• W4315866019 hasConceptScore W4315866019C71924100 @default.
• W4315866019 hasConceptScore W4315866019C84393581 @default.
• W4315866019 hasFunder F4320322861 @default.
• W4315866019 hasIssue "1" @default.
• W4315866019 hasLocation W43158660191 @default.
• W4315866019 hasLocation W43158660192 @default.
• W4315866019 hasLocation W43158660193 @default.
• W4315866019 hasOpenAccess W4315866019 @default.
• W4315866019 hasPrimaryLocation W43158660191 @default.
• W4315866019 hasRelatedWork W1094797422 @default.
• W4315866019 hasRelatedWork W138949052 @default.
• W4315866019 hasRelatedWork W1481896486 @default.
• W4315866019 hasRelatedWork W2022469420 @default.
• W4315866019 hasRelatedWork W2072664714 @default.
• W4315866019 hasRelatedWork W2128109138 @default.
• W4315866019 hasRelatedWork W2155045291 @default.
• W4315866019 hasRelatedWork W3092315635 @default.
• W4315866019 hasRelatedWork W4255613446 @default.
• W4315866019 hasRelatedWork W4315866019 @default.
• W4315866019 hasVolume "13" @default.

• next