FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4316079892> ?p ?o ?g. }

• W4316079892 endingPage "e787" @default.
• W4316079892 startingPage "e786" @default.
• W4316079892 abstract "Introduction: Post-operative pancreatic fluid collections (POPFCs) remain a significant source of morbidity after distal pancreatectomy. Drainage can be performed using percutaneous or endoscopic approaches, but comparative data are limited. This study compared endoscopic ultrasound-guided drainage (EUSD) with percutaneous drainage (PTD) in the management of symptomatic POPFCs after distal pancreatectomy. The primary aim is to compare rates of clinical success, defined as symptomatic improvement and radiographic resolution without requiring an alternate drainage modality. Secondary outcomes included technical success, total number of interventions, time to resolution, rates of adverse events (AEs), and POPFC recurrence. Methods: Adults who underwent distal pancreatectomy from January 2012 to August 2021 and developed symptomatic POPFC were identified retrospectively from a single academic center electronic medical record and a prospectively maintained pancreatic surgery database. Demographic data, procedural data, and clinical outcomes were abstracted. Quantitative variables were described with median and interquartile ranges and compared using a two-tailed t-test. In addition, categorical data were reported as frequencies and compared using Chi-squared or Fisher exact tests. Results: Of 1046 patients that underwent distal pancreatectomy, 217 met study inclusion criteria (median age 60 years, 51.2% female) of whom 106 underwent EUSD and 111 PTD. There were no significant differences in baseline characteristics including age, gender, pathology, and POPFC size (Table). PTD was generally performed earlier after surgery (10 vs. 27 days; p = < 0.001) and more commonly in the inpatient setting (82.9% vs. 49.1%; p≤0.001). EUSD was associated with a significantly higher rate of clinical success (92.5% vs. 76.6%; p=0.001), fewer median number of interventions (2 vs. 4; p≤0.001), and lower rate of POPFC recurrence (7.6% vs. 20.7%; p=0.007). Drain dwell time was shorter for patients who underwent PTD (37 vs. 46 days; p=0.013). AEs were more frequent after EUSD but did not reach a level of statistical significance (10.4% vs 6.3%, p=0.28); with approximately 1/3 of EUSD AEs due to stent migration. Conclusion: In patients with POPFCs after distal pancreatectomy, EUSD was associated with higher rates of clinical success, fewer interventions, and lower rates of recurrence. EUSD should be considered for management of POPFCs in centers with technical expertise. Table 1. - Baseline characteristics and clinical outcomes of patients who developed post-operative pancreatic fluid collections after distal pancreatectomy Baseline Characteristics EUSDN =106 PTDN = 111 P value Age, years, median (IQR) 60 (48-68) 60 (55-68.5) 0.09 Female, no. (%) 52(49.1) 59 (53.1) 0.54 Laparoscopic surgery, no. (%) 56 (52.8) 34(30.6) 0.002 Pancreatic pathology, no. (%) Ductal adenocarcinoma 43 (31.1) 40 (29.7) Neuroendocrine tumor 32 (30.2) 33 (29.7) Intraductal papillary mucinous neoplasm 12 (11.3) 8 (7.2) Other* 19 (17.9) 30 (27.0) Inpatient, no. (%) 52 (49.1) 92(82.9) < 0.001 Presence of solid necrosis, no. (%) 48 (45.3) 11 (9.9) < 0.001 Infected POPFC, no. (%) 42 (39.6) 30 (27.0) 0.06 Maximum diameter in cm, Median (IQR) 7.4 (5.2-10.0) 6.7 (5.1-10.0) 0.45 Time to drainage from surgery, days, median (IQR) 27.0 (13.5-46.5) 10.0 (7.00-18.3) < 0.001 Clinical Outcomes Clinical success, no. (%) 98 (92.5) 85 (76.6) 0.001 Technical success, no. (%) 106(100) 111(100) Procedure related adverse events, no. (%) 11(10.4) 7 (6.3) 0.28 Number of interventions, median (IQR) 2 (2-4) 4 (2-6) < 0.001 Time to drain removal, days, median, (IQR) 45.5 (31.5-73.0) 37.0 (24.0-61.0) 0.013 Recurrence, no. (%) 8 (7.6) 23 (20.7) 0.007 Footnotes: EUSD: EUS-guided drainage; PTD: Percutaneous drainage; POPFC: Post-operative pancreatic fluid collection*Other pathologies: serous cystadenoma (EUSD n=2; PTD n=3), sarcoma (EUSD n=3; PTD n=6), chronic pancreatitis (EUSD n=3; PTD n=5), insulinoma (EUSD n=1; PTD n=5), other metastatic disease (EUSD n=10; PTD n=11)." @default.
• W4316079892 created "2023-01-14" @default.
• W4316079892 creator A5003186777 @default.
• W4316079892 creator A5021484771 @default.
• W4316079892 creator A5023511246 @default.
• W4316079892 creator A5024716486 @default.
• W4316079892 creator A5027964181 @default.
• W4316079892 creator A5029404091 @default.
• W4316079892 creator A5045243510 @default.
• W4316079892 creator A5048254823 @default.
• W4316079892 creator A5053091398 @default.
• W4316079892 creator A5058793400 @default.
• W4316079892 creator A5077228556 @default.
• W4316079892 creator A5084018434 @default.
• W4316079892 creator A5030054803 @default.
• W4316079892 date "2022-10-01" @default.
• W4316079892 modified "2023-10-14" @default.
• W4316079892 title "S1084 Endoscopic Ultrasound-Guided vs Percutaneous Drainage for the Management of Post-Operative Pancreatic Fluid Collections After Distal Pancreatectomy" @default.
• W4316079892 doi "https://doi.org/10.14309/01.ajg.0000860976.97794.c6" @default.
• W4316079892 hasPublicationYear "2022" @default.
• W4316079892 type Work @default.
• W4316079892 citedByCount "0" @default.
• W4316079892 crossrefType "journal-article" @default.
• W4316079892 hasAuthorship W4316079892A5003186777 @default.
• W4316079892 hasAuthorship W4316079892A5021484771 @default.
• W4316079892 hasAuthorship W4316079892A5023511246 @default.
• W4316079892 hasAuthorship W4316079892A5024716486 @default.
• W4316079892 hasAuthorship W4316079892A5027964181 @default.
• W4316079892 hasAuthorship W4316079892A5029404091 @default.
• W4316079892 hasAuthorship W4316079892A5030054803 @default.
• W4316079892 hasAuthorship W4316079892A5045243510 @default.
• W4316079892 hasAuthorship W4316079892A5048254823 @default.
• W4316079892 hasAuthorship W4316079892A5053091398 @default.
• W4316079892 hasAuthorship W4316079892A5058793400 @default.
• W4316079892 hasAuthorship W4316079892A5077228556 @default.
• W4316079892 hasAuthorship W4316079892A5084018434 @default.
• W4316079892 hasBestOaLocation W43160798921 @default.
• W4316079892 hasConcept C119060515 @default.
• W4316079892 hasConcept C141071460 @default.
• W4316079892 hasConcept C159110652 @default.
• W4316079892 hasConcept C195910791 @default.
• W4316079892 hasConcept C2775967933 @default.
• W4316079892 hasConcept C2778494859 @default.
• W4316079892 hasConcept C2780390042 @default.
• W4316079892 hasConcept C2780813298 @default.
• W4316079892 hasConcept C71924100 @default.
• W4316079892 hasConceptScore W4316079892C119060515 @default.
• W4316079892 hasConceptScore W4316079892C141071460 @default.
• W4316079892 hasConceptScore W4316079892C159110652 @default.
• W4316079892 hasConceptScore W4316079892C195910791 @default.
• W4316079892 hasConceptScore W4316079892C2775967933 @default.
• W4316079892 hasConceptScore W4316079892C2778494859 @default.
• W4316079892 hasConceptScore W4316079892C2780390042 @default.
• W4316079892 hasConceptScore W4316079892C2780813298 @default.
• W4316079892 hasConceptScore W4316079892C71924100 @default.
• W4316079892 hasIssue "10S" @default.
• W4316079892 hasLocation W43160798921 @default.
• W4316079892 hasLocation W43160798922 @default.
• W4316079892 hasOpenAccess W4316079892 @default.
• W4316079892 hasPrimaryLocation W43160798921 @default.
• W4316079892 hasRelatedWork W1978658947 @default.
• W4316079892 hasRelatedWork W2007480558 @default.
• W4316079892 hasRelatedWork W2008878688 @default.
• W4316079892 hasRelatedWork W2010762426 @default.
• W4316079892 hasRelatedWork W2076812396 @default.
• W4316079892 hasRelatedWork W2086150032 @default.
• W4316079892 hasRelatedWork W2135221496 @default.
• W4316079892 hasRelatedWork W2157448707 @default.
• W4316079892 hasRelatedWork W2977919527 @default.
• W4316079892 hasRelatedWork W3032124713 @default.
• W4316079892 hasVolume "117" @default.
• W4316079892 isParatext "false" @default.
• W4316079892 isRetracted "false" @default.
• W4316079892 workType "article" @default.