FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4316082209> ?p ?o ?g. }

• W4316082209 endingPage "e1422" @default.
• W4316082209 startingPage "e1421" @default.
• W4316082209 abstract "Introduction: Non-Hodgkin lymphoma (NHL) is a notable hematologic malignancy that may emerge as nodal or extra-nodal. Mucosa-Associated Lymphoid Tissue (MALT) Lymphomas account for 5-10% of NHLs, of which most are in the stomach and intestines due to H. Pylori’s significant role in their development. Colonic involvement is poorly understood and accounts for only 2.5% of MALT lymphomas, making it an extremely rare occurrence. Most MALT lymphomas present as a single polypoid lesion or submucosal tumor. We bring to light a case of a colonic MALT lymphoma that was found during a screening colonoscopy. Case Description/Methods: A 59-year-old male patient with a personal history of colon polyps presented for a screening colonoscopy in 2018. His last procedure in 2013 concluded with the resection of 3 tubular adenomatous polyps necessitating repeat colonoscopy in 5 years. Upon presentation, patient denied any fever, chills, night sweats, or unintentional weight loss. Colonoscopy was done and revealed a 5mm sessile polyp in the ascending colon that was removed with hot snare as well as 2 4mm sessile polyps in the ascending and descending colon that were removed by cold snare. Biopsy report of the 5mm polyp revealed extra-nodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT) of low-grade histology. Tissue sample was CD20+, BCL2+, and stained about 15-20% with Ki67 immunostaining. H. pylori stool antigen testing was negative. Patient was referred to the oncology team for further management. PET scan did not show any evidence of widespread disease. Bone marrow core biopsy and aspirate showed normocellular bone marrow with no evidence of lymphoma involvement. No further intervention was done. A colonoscopy was planned after 3 years for tumor surveillance. Procedure was done in 2022 and showed no polyps, highlighting complete resection of the previous 5mm MALT lymphoma polyp in the colon (Figure 1). Discussion: Colonic MALT lymphoma is a rare subtype of extra-nodal marginal zone lymphoma (EMZL) and a proper treatment guideline is yet to be established. Surgical resection, chemotherapy and/or radiotherapy have been previously used successfully in establishing remission. Curative endoscopic resection is an option for localized EMZL and patients can be followed with close observation without any further aggressive therapies.Figure 1.: A, H&E ×100 (Thick arrows: small lymphoid cells; thin arrows: residual germinal center) (B) CD20 ×100 (stains both small lymphoid cells and the germinal center) (C) BCL2 ×100 (stains both T and B cells) (D) BCL6 ×100 (stains B cells in the residual “moth-eaten” germinal center)." @default.
• W4316082209 created "2023-01-14" @default.
• W4316082209 creator A5023661233 @default.
• W4316082209 creator A5039846483 @default.
• W4316082209 creator A5052612037 @default.
• W4316082209 creator A5080264426 @default.
• W4316082209 creator A5089582418 @default.
• W4316082209 creator A5090912580 @default.
• W4316082209 date "2022-10-01" @default.
• W4316082209 modified "2023-09-27" @default.
• W4316082209 title "S2083 Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma of the Colon" @default.
• W4316082209 doi "https://doi.org/10.14309/01.ajg.0000864972.42722.f6" @default.
• W4316082209 hasPublicationYear "2022" @default.
• W4316082209 type Work @default.
• W4316082209 citedByCount "0" @default.
• W4316082209 crossrefType "journal-article" @default.
• W4316082209 hasAuthorship W4316082209A5023661233 @default.
• W4316082209 hasAuthorship W4316082209A5039846483 @default.
• W4316082209 hasAuthorship W4316082209A5052612037 @default.
• W4316082209 hasAuthorship W4316082209A5080264426 @default.
• W4316082209 hasAuthorship W4316082209A5089582418 @default.
• W4316082209 hasAuthorship W4316082209A5090912580 @default.
• W4316082209 hasBestOaLocation W43160822091 @default.
• W4316082209 hasConcept C121608353 @default.
• W4316082209 hasConcept C126322002 @default.
• W4316082209 hasConcept C142724271 @default.
• W4316082209 hasConcept C181152851 @default.
• W4316082209 hasConcept C2775934546 @default.
• W4316082209 hasConcept C2778435480 @default.
• W4316082209 hasConcept C2779338263 @default.
• W4316082209 hasConcept C2779526237 @default.
• W4316082209 hasConcept C2779851268 @default.
• W4316082209 hasConcept C2780833581 @default.
• W4316082209 hasConcept C526805850 @default.
• W4316082209 hasConcept C71924100 @default.
• W4316082209 hasConcept C90924648 @default.
• W4316082209 hasConceptScore W4316082209C121608353 @default.
• W4316082209 hasConceptScore W4316082209C126322002 @default.
• W4316082209 hasConceptScore W4316082209C142724271 @default.
• W4316082209 hasConceptScore W4316082209C181152851 @default.
• W4316082209 hasConceptScore W4316082209C2775934546 @default.
• W4316082209 hasConceptScore W4316082209C2778435480 @default.
• W4316082209 hasConceptScore W4316082209C2779338263 @default.
• W4316082209 hasConceptScore W4316082209C2779526237 @default.
• W4316082209 hasConceptScore W4316082209C2779851268 @default.
• W4316082209 hasConceptScore W4316082209C2780833581 @default.
• W4316082209 hasConceptScore W4316082209C526805850 @default.
• W4316082209 hasConceptScore W4316082209C71924100 @default.
• W4316082209 hasConceptScore W4316082209C90924648 @default.
• W4316082209 hasIssue "10S" @default.
• W4316082209 hasLocation W43160822091 @default.
• W4316082209 hasLocation W43160822092 @default.
• W4316082209 hasOpenAccess W4316082209 @default.
• W4316082209 hasPrimaryLocation W43160822091 @default.
• W4316082209 hasRelatedWork W173502416 @default.
• W4316082209 hasRelatedWork W1981877216 @default.
• W4316082209 hasRelatedWork W2024166118 @default.
• W4316082209 hasRelatedWork W2024680513 @default.
• W4316082209 hasRelatedWork W2044851246 @default.
• W4316082209 hasRelatedWork W2059169594 @default.
• W4316082209 hasRelatedWork W2079485481 @default.
• W4316082209 hasRelatedWork W2104634375 @default.
• W4316082209 hasRelatedWork W2491222318 @default.
• W4316082209 hasRelatedWork W3021040965 @default.
• W4316082209 hasVolume "117" @default.
• W4316082209 isParatext "false" @default.
• W4316082209 isRetracted "false" @default.
• W4316082209 workType "article" @default.