Matches in SemOpenAlex for { <https://semopenalex.org/work/W4316084514> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W4316084514 endingPage "e2216" @default.
- W4316084514 startingPage "e2215" @default.
- W4316084514 abstract "Introduction: IgA Vasculitis is a small vessel vasculitis that is commonly seen in children but rarely affects adults. IgA Vasculitis can present as arthralgia, rash, kidney involvement, and gastrointestinal symptoms. We present a case of a 56 years old Male that presented with abdominal pain without the characteristic purpuric rash or any other features. Imaging findings showed enteritis, colonoscopy showed ulcers in the terminal ileum, rectum, sigmoid and descending colon. The Kidney biopsy showed IgA deposition. Thus, adult-onset IgA vasculitis can present with gastrointestinal symptoms without the typical skin manifestations and imaging and endoscopy can guide in diagnosis and management of the same. Case Description/Methods: We present a case of a 56 years old Male who presented to the ED with abdominal pain and arthralgia without the characteristic skin purpura. Abdominal imaging showed severe diffuse wall thickening of multiple loops of small bowel with adjacent fat stranding. Small bowel enteroscopy was performed that showed many non-bleeding cratered ulcers in the duodenum and jejunum, and colonoscopy showed ulcers in the terminal ileum, rectum, sigmoid and descending colon. Biopsy from Duodenal and Jejunal ulcers showed focal acute and chronic inflammation and ulceration. A kidney biopsy showed IgA deposition. The patient’s abdominal pain rapidly resolved after steroid administration and supportive care. (Figure) Discussion: IgA Vasculitis is a small vessel vasculitis that affects various organs, including the skin, gastrointestinal (GI) tract, joints, and kidneys and commonly occurs in children. The incidence of IgA Vasculitis in adults is as low as 0.8-1.8/100 000 for adults. Approximately 53% of patients with adult IgA vasculitis have Gastrointestinal involvement. Gastrointestinal manifestations range from mild (nausea, vomiting, abdominal pain, paralytic ileus) to severe findings (gastrointestinal bleeding, intussusception, bowel ischemia with secondary necrosis, bowel perforation). Abdominal pain is the most common gastrointestinal symptom which is attributed to mesenteric vasculitis leading to bowel ischemia and edema of the gastrointestinal tract. The small bowel, and in particular, the duodenum is the most commonly affected site. Vasculitis is not commonly observed in GI biopsies. While the clinical and histologic findings may mimic early inflammatory bowel disease, the presence of predominant small bowel involvement, especially erosive duodenitis, should raise suspicion for IgA vasculitis.Figure 1.: Endoscopic and Colonoscopic Findings in IgA Vasculitis." @default.
- W4316084514 created "2023-01-14" @default.
- W4316084514 creator A5023711742 @default.
- W4316084514 creator A5085498876 @default.
- W4316084514 creator A5007225155 @default.
- W4316084514 date "2022-10-01" @default.
- W4316084514 modified "2023-09-23" @default.
- W4316084514 title "S3530 A Rare Presentation of Adult Onset IgA Vasculitis With Gastrointestinal Manifestations Without Typical Skin Manifestations" @default.
- W4316084514 doi "https://doi.org/10.14309/01.ajg.0000870760.95350.4d" @default.
- W4316084514 hasPublicationYear "2022" @default.
- W4316084514 type Work @default.
- W4316084514 citedByCount "0" @default.
- W4316084514 crossrefType "journal-article" @default.
- W4316084514 hasAuthorship W4316084514A5007225155 @default.
- W4316084514 hasAuthorship W4316084514A5023711742 @default.
- W4316084514 hasAuthorship W4316084514A5085498876 @default.
- W4316084514 hasBestOaLocation W43160845141 @default.
- W4316084514 hasConcept C121608353 @default.
- W4316084514 hasConcept C126322002 @default.
- W4316084514 hasConcept C142724271 @default.
- W4316084514 hasConcept C18903297 @default.
- W4316084514 hasConcept C2775934546 @default.
- W4316084514 hasConcept C2776015282 @default.
- W4316084514 hasConcept C2776809568 @default.
- W4316084514 hasConcept C2776870353 @default.
- W4316084514 hasConcept C2777121669 @default.
- W4316084514 hasConcept C2778292851 @default.
- W4316084514 hasConcept C2778435480 @default.
- W4316084514 hasConcept C2778570526 @default.
- W4316084514 hasConcept C2779134260 @default.
- W4316084514 hasConcept C2780013240 @default.
- W4316084514 hasConcept C2780439664 @default.
- W4316084514 hasConcept C2780955771 @default.
- W4316084514 hasConcept C2781074409 @default.
- W4316084514 hasConcept C2781222656 @default.
- W4316084514 hasConcept C526805850 @default.
- W4316084514 hasConcept C71924100 @default.
- W4316084514 hasConcept C86803240 @default.
- W4316084514 hasConcept C90924648 @default.
- W4316084514 hasConceptScore W4316084514C121608353 @default.
- W4316084514 hasConceptScore W4316084514C126322002 @default.
- W4316084514 hasConceptScore W4316084514C142724271 @default.
- W4316084514 hasConceptScore W4316084514C18903297 @default.
- W4316084514 hasConceptScore W4316084514C2775934546 @default.
- W4316084514 hasConceptScore W4316084514C2776015282 @default.
- W4316084514 hasConceptScore W4316084514C2776809568 @default.
- W4316084514 hasConceptScore W4316084514C2776870353 @default.
- W4316084514 hasConceptScore W4316084514C2777121669 @default.
- W4316084514 hasConceptScore W4316084514C2778292851 @default.
- W4316084514 hasConceptScore W4316084514C2778435480 @default.
- W4316084514 hasConceptScore W4316084514C2778570526 @default.
- W4316084514 hasConceptScore W4316084514C2779134260 @default.
- W4316084514 hasConceptScore W4316084514C2780013240 @default.
- W4316084514 hasConceptScore W4316084514C2780439664 @default.
- W4316084514 hasConceptScore W4316084514C2780955771 @default.
- W4316084514 hasConceptScore W4316084514C2781074409 @default.
- W4316084514 hasConceptScore W4316084514C2781222656 @default.
- W4316084514 hasConceptScore W4316084514C526805850 @default.
- W4316084514 hasConceptScore W4316084514C71924100 @default.
- W4316084514 hasConceptScore W4316084514C86803240 @default.
- W4316084514 hasConceptScore W4316084514C90924648 @default.
- W4316084514 hasIssue "10S" @default.
- W4316084514 hasLocation W43160845141 @default.
- W4316084514 hasLocation W43160845142 @default.
- W4316084514 hasOpenAccess W4316084514 @default.
- W4316084514 hasPrimaryLocation W43160845141 @default.
- W4316084514 hasRelatedWork W2044658514 @default.
- W4316084514 hasRelatedWork W2108412586 @default.
- W4316084514 hasRelatedWork W2514316307 @default.
- W4316084514 hasRelatedWork W273221 @default.
- W4316084514 hasRelatedWork W2910050689 @default.
- W4316084514 hasRelatedWork W2951261786 @default.
- W4316084514 hasRelatedWork W3015662486 @default.
- W4316084514 hasRelatedWork W3109454459 @default.
- W4316084514 hasRelatedWork W3194855222 @default.
- W4316084514 hasRelatedWork W4317462624 @default.
- W4316084514 hasVolume "117" @default.
- W4316084514 isParatext "false" @default.
- W4316084514 isRetracted "false" @default.
- W4316084514 workType "article" @default.