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- W4316097030 abstract "Triazoles, a five-membered ring structure and three nitrogen atoms, are regarded as important building blocks for the synthesis of numerous organic compounds. Triazoles and their derivatives have received considerable attention over the past decade due to their chemotherapeutic value. It’s been thought to be a functional core that exhibits most varieties of biological activity mainly antibiotics, antimicrobials and antifungals. In present work, a series of novel substituted triazole phenylmethanones were synthesized using Claisen-Schmidt condensation reaction of 1-(5-methyl-1-(substituted phenyl)-1H- 1,2,3-triazol-4-yl)-ethan-1-one (3a-d) and some aromatic aldehydes. Final compounds (5a-f) were synthesized from compounds 4a-d, hydrazine hydrate and benzoic acid by sequential reactions having intermolecular conjugate addition and formation of hydrazone. All the intermediate and final compounds were characterized from the mass, elemental and 1H NMR spectral data." @default.
- W4316097030 created "2023-01-14" @default.
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- W4316097030 date "2023-01-01" @default.
- W4316097030 modified "2023-09-26" @default.
- W4316097030 title "Design, Synthesis and Evaluation of Some Substituted Triazole Phenyl Methanones from Substituted Anilines" @default.
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- W4316097030 doi "https://doi.org/10.14233/ajomc.2022.ajomc-p405" @default.
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