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• W4316171103 abstract "ABSTRACT Introduction Income, a component of socioeconomic status, influences cancer risk as a social determinant of health. We evaluated the independent associations between individual- and area-level income, and site-specific cancer incidence in Canada. Methods We used data from the 2006 and 2011 Canadian Census Health and Environment Cohorts, which are probabilistically linked datasets constituted by 5.9 million and 6.5 million respondents of the 2006 Canadian long-form census and 2011 National Household Survey, respectively. Individuals were linked to the Canadian Cancer Registry through 2015. Individual-level income was derived using after-tax household income adjusted for household size. Annual tax return postal codes were used to assign area-level household income quintiles to individuals for each year of follow-up. We calculated age-standardized incidence rates (ASIR) and rate ratios for cancers overall and by site. We conducted multivariable negative binomial regression to adjust these rates for other demographic and socioeconomic variables. Results Individuals of lower individual- and area-level income had higher ASIRs compared to those in the wealthiest income quintile for head and neck, oropharyngeal, esophageal, stomach, colorectal, anal, liver, pancreas, lung, cervical, and kidney and renal pelvis cancers. Conversely, individuals of wealthier individual- and area-level income had higher ASIRs for melanoma, leukemia, Hodgkin’s lymphoma, and non-Hodgkin’s lymphoma, breast, uterine, prostate, and testicular cancers. Most differences in site-specific incidence by income quintile remained after adjustment. Conclusions Although Canada’s publicly funded healthcare system provides universal coverage, inequalities in cancer incidence persist across individual- and area-level income gradients. Our estimates suggest that individual- and area-level income affect cancer incidence through independent mechanisms." @default.
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• W4316171103 date "2023-01-14" @default.
• W4316171103 modified "2023-09-26" @default.
• W4316171103 title "Differences in site-specific cancer incidence by individual- and area-level income in Canada from 2006-2015" @default.
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• W4316171103 doi "https://doi.org/10.1101/2023.01.13.23284277" @default.
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