Matches in SemOpenAlex for { <https://semopenalex.org/work/W4316363085> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W4316363085 abstract "Paracetamol or acetaminophen is the main non-opioid analgesic recommended for mild pain by the World Health Organization (WHO) analgesic ladder. However, the high levels used of paracetamol are associated with the hepatotoxicity and nephrotoxicity caused by accumulation of toxic metabolites. The sensor is produced on a polyester substrate containing a full electrochemical device with working, auxiliary, and reference electrodes in which, guiding personalized medicine solutions are not reported. Temporal paracetamol profiles in human saliva are performed with the subject taking different amounts of commercial analgesic pills. The variation of saliva paracetamol levels is demonstrated to be interference free from electroactive interfering species and human saliva constituents. In addition, the sensor displays to be useful as a disposable device for the fast detection of paracetamol in untreated raw saliva following pill intake. The maximum concentration (Cmax ) and half-life time (t1/2 ) for paracetamol are 143.27 µm and 110 min. The results demonstrate the potential of a simple strategy with electrochemical devices for noninvasive personalized therapy toward guiding drug interventions through tracking of active substance, detecting, and correcting insufficiency of absorption to meet individual needs avoiding overdoses, side effects, and intoxication." @default.
- W4316363085 created "2023-01-16" @default.
- W4316363085 creator A5044005471 @default.
- W4316363085 creator A5058151073 @default.
- W4316363085 date "2023-01-15" @default.
- W4316363085 modified "2023-10-14" @default.
- W4316363085 title "On‐Site Therapeutic Drug Monitoring of Paracetamol Analgesic in Non‐Invasively Collected Saliva for Personalized Medicine" @default.
- W4316363085 cites W2014345244 @default.
- W4316363085 cites W2030003382 @default.
- W4316363085 cites W2045478673 @default.
- W4316363085 cites W2081017554 @default.
- W4316363085 cites W2095197048 @default.
- W4316363085 cites W2166107397 @default.
- W4316363085 cites W2535760173 @default.
- W4316363085 cites W2623016528 @default.
- W4316363085 cites W2767054373 @default.
- W4316363085 cites W2954863339 @default.
- W4316363085 cites W2963894332 @default.
- W4316363085 cites W2963990809 @default.
- W4316363085 cites W2980938923 @default.
- W4316363085 cites W3015167435 @default.
- W4316363085 cites W3022153897 @default.
- W4316363085 cites W3023922670 @default.
- W4316363085 cites W3045885690 @default.
- W4316363085 cites W3080420889 @default.
- W4316363085 cites W3092043166 @default.
- W4316363085 cites W3120768973 @default.
- W4316363085 cites W3159782416 @default.
- W4316363085 cites W3163885195 @default.
- W4316363085 cites W3166292103 @default.
- W4316363085 cites W3194575042 @default.
- W4316363085 cites W3200333504 @default.
- W4316363085 cites W4200165476 @default.
- W4316363085 cites W4205284554 @default.
- W4316363085 cites W4210347423 @default.
- W4316363085 cites W4229456303 @default.
- W4316363085 cites W4243712096 @default.
- W4316363085 cites W4251342409 @default.
- W4316363085 cites W4281793692 @default.
- W4316363085 doi "https://doi.org/10.1002/smll.202206753" @default.
- W4316363085 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36642790" @default.
- W4316363085 hasPublicationYear "2023" @default.
- W4316363085 type Work @default.
- W4316363085 citedByCount "2" @default.
- W4316363085 countsByYear W43163630852023 @default.
- W4316363085 crossrefType "journal-article" @default.
- W4316363085 hasAuthorship W4316363085A5044005471 @default.
- W4316363085 hasAuthorship W4316363085A5058151073 @default.
- W4316363085 hasConcept C126322002 @default.
- W4316363085 hasConcept C2777389121 @default.
- W4316363085 hasConcept C2777866328 @default.
- W4316363085 hasConcept C2778722691 @default.
- W4316363085 hasConcept C2780035454 @default.
- W4316363085 hasConcept C2780820201 @default.
- W4316363085 hasConcept C504460877 @default.
- W4316363085 hasConcept C71924100 @default.
- W4316363085 hasConcept C98274493 @default.
- W4316363085 hasConceptScore W4316363085C126322002 @default.
- W4316363085 hasConceptScore W4316363085C2777389121 @default.
- W4316363085 hasConceptScore W4316363085C2777866328 @default.
- W4316363085 hasConceptScore W4316363085C2778722691 @default.
- W4316363085 hasConceptScore W4316363085C2780035454 @default.
- W4316363085 hasConceptScore W4316363085C2780820201 @default.
- W4316363085 hasConceptScore W4316363085C504460877 @default.
- W4316363085 hasConceptScore W4316363085C71924100 @default.
- W4316363085 hasConceptScore W4316363085C98274493 @default.
- W4316363085 hasFunder F4320320997 @default.
- W4316363085 hasFunder F4320322025 @default.
- W4316363085 hasIssue "12" @default.
- W4316363085 hasLocation W43163630851 @default.
- W4316363085 hasLocation W43163630852 @default.
- W4316363085 hasOpenAccess W4316363085 @default.
- W4316363085 hasPrimaryLocation W43163630851 @default.
- W4316363085 hasRelatedWork W107440495 @default.
- W4316363085 hasRelatedWork W1973213819 @default.
- W4316363085 hasRelatedWork W1983842309 @default.
- W4316363085 hasRelatedWork W2078505343 @default.
- W4316363085 hasRelatedWork W2084704851 @default.
- W4316363085 hasRelatedWork W2246533331 @default.
- W4316363085 hasRelatedWork W2393154874 @default.
- W4316363085 hasRelatedWork W2588261587 @default.
- W4316363085 hasRelatedWork W2992901729 @default.
- W4316363085 hasRelatedWork W66115843 @default.
- W4316363085 hasVolume "19" @default.
- W4316363085 isParatext "false" @default.
- W4316363085 isRetracted "false" @default.
- W4316363085 workType "article" @default.