Matches in SemOpenAlex for { <https://semopenalex.org/work/W4316369328> ?p ?o ?g. }
- W4316369328 endingPage "7419" @default.
- W4316369328 startingPage "7379" @default.
- W4316369328 abstract "For decades now, photoacoustic imaging (PAI) has been investigated to realize its potential as a niche biomedical imaging modality. Despite its highly desirable optical contrast and ultrasonic spatiotemporal resolution, PAI is challenged by such physical limitations as a low signal-to-noise ratio (SNR), diminished image contrast due to strong optical attenuation, and a lower-bound on spatial resolution in deep tissue. In addition, contrast-enhanced PAI has faced practical limitations such as insufficient cell-specific targeting due to low delivery efficiency and difficulties in developing clinically translatable agents. Identifying these limitations is essential to the continuing expansion of the field, and substantial advances in developing contrast-enhancing agents, complemented by high-performance image acquisition systems, have synergistically dealt with the challenges of conventional PAI. This review covers the past four years of research on pushing the physical and practical challenges of PAI in terms of SNR/contrast, spatial resolution, targeted delivery, and clinical application. Promising strategies for dealing with each challenge are reviewed in detail, and future research directions for next generation contrast-enhanced PAI are discussed." @default.
- W4316369328 created "2023-01-16" @default.
- W4316369328 creator A5006397694 @default.
- W4316369328 creator A5035462625 @default.
- W4316369328 creator A5056195378 @default.
- W4316369328 creator A5071232002 @default.
- W4316369328 creator A5089452948 @default.
- W4316369328 creator A5091718941 @default.
- W4316369328 date "2023-01-16" @default.
- W4316369328 modified "2023-10-16" @default.
- W4316369328 title "Recent Advances in Contrast-Enhanced Photoacoustic Imaging: Overcoming the Physical and Practical Challenges" @default.
- W4316369328 cites W1595241211 @default.
- W4316369328 cites W1639394602 @default.
- W4316369328 cites W1838846301 @default.
- W4316369328 cites W1859615259 @default.
- W4316369328 cites W1965950298 @default.
- W4316369328 cites W1967905489 @default.
- W4316369328 cites W1970412285 @default.
- W4316369328 cites W1972504893 @default.
- W4316369328 cites W1974139656 @default.
- W4316369328 cites W1978337610 @default.
- W4316369328 cites W1979507175 @default.
- W4316369328 cites W1987423979 @default.
- W4316369328 cites W1990189624 @default.
- W4316369328 cites W1992009035 @default.
- W4316369328 cites W1992858116 @default.
- W4316369328 cites W1993748326 @default.
- W4316369328 cites W1995971025 @default.
- W4316369328 cites W1997431187 @default.
- W4316369328 cites W2003184295 @default.
- W4316369328 cites W2005834295 @default.
- W4316369328 cites W2007363051 @default.
- W4316369328 cites W2012099137 @default.
- W4316369328 cites W2012534987 @default.
- W4316369328 cites W2014358738 @default.
- W4316369328 cites W2019189459 @default.
- W4316369328 cites W2019493368 @default.
- W4316369328 cites W2019775599 @default.
- W4316369328 cites W2022228342 @default.
- W4316369328 cites W2023074414 @default.
- W4316369328 cites W2023812730 @default.
- W4316369328 cites W2025276450 @default.
- W4316369328 cites W2026343913 @default.
- W4316369328 cites W2030964111 @default.
- W4316369328 cites W2031338189 @default.
- W4316369328 cites W2034593954 @default.
- W4316369328 cites W2036713511 @default.
- W4316369328 cites W2036969572 @default.
- W4316369328 cites W2039086627 @default.
- W4316369328 cites W2041243298 @default.
- W4316369328 cites W2042410935 @default.
- W4316369328 cites W2044532395 @default.
- W4316369328 cites W2046894146 @default.
- W4316369328 cites W2048742429 @default.
- W4316369328 cites W2054455698 @default.
- W4316369328 cites W2054496327 @default.
- W4316369328 cites W2061707289 @default.
- W4316369328 cites W2062560051 @default.
- W4316369328 cites W2063589313 @default.
- W4316369328 cites W2064753738 @default.
- W4316369328 cites W2065023892 @default.
- W4316369328 cites W2066269543 @default.
- W4316369328 cites W2067302091 @default.
- W4316369328 cites W2068638954 @default.
- W4316369328 cites W2068926508 @default.
- W4316369328 cites W2069848052 @default.
- W4316369328 cites W2070772667 @default.
- W4316369328 cites W2071591536 @default.
- W4316369328 cites W2071689705 @default.
- W4316369328 cites W2075421578 @default.
- W4316369328 cites W2076794464 @default.
- W4316369328 cites W2077129358 @default.
- W4316369328 cites W2079448771 @default.
- W4316369328 cites W2082373874 @default.
- W4316369328 cites W2083952346 @default.
- W4316369328 cites W2085564184 @default.
- W4316369328 cites W2085836649 @default.
- W4316369328 cites W2086829711 @default.
- W4316369328 cites W2089901886 @default.
- W4316369328 cites W2093560200 @default.
- W4316369328 cites W2095648002 @default.
- W4316369328 cites W2096097264 @default.
- W4316369328 cites W2096952219 @default.
- W4316369328 cites W2100635475 @default.
- W4316369328 cites W2102728045 @default.
- W4316369328 cites W2106739895 @default.
- W4316369328 cites W2109329707 @default.
- W4316369328 cites W2112227276 @default.
- W4316369328 cites W2115318943 @default.
- W4316369328 cites W2115690563 @default.
- W4316369328 cites W2116916132 @default.
- W4316369328 cites W2117570650 @default.
- W4316369328 cites W2120125712 @default.
- W4316369328 cites W2126392408 @default.
- W4316369328 cites W2128158781 @default.
- W4316369328 cites W2131349906 @default.
- W4316369328 cites W2135295464 @default.
- W4316369328 cites W2135856533 @default.