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- W4316500424 abstract "Experimental Allergic Encephalomyelitis (EAE) is an autoimmune disease of the central nervous system, which was found accidentally from the occurrence of rabies post-vaccinal encephalomyelitis. Although the mouse is an ideal experimental animal for the immunologic studies, the determination of encephalitogenic epitopes had been difficult because of the relative resistance of mice to induction of EAE. EAE in monkey is of considerable interest due to its closer relevance to human demyelinating disease such as multiple sclerosis; however, it is very difficult to define the exact encephalitogenic sequence. Several regions of Myelin Basic Protein (MBP) have been reported to be encephalitogenic in monkey. The possibility of contaminating MBP and lipids is higher in the classical method, while these substances are well separated from Proteolipid Apoprotein by the column chromatography." @default.
- W4316500424 created "2023-01-16" @default.
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- W4316500424 date "2023-01-16" @default.
- W4316500424 modified "2023-10-16" @default.
- W4316500424 title "Strain and Species Differences of Encephalitogenic Determinants of Myelin Basic Protein and Proteolipid Apoprotein" @default.
- W4316500424 doi "https://doi.org/10.1201/9780203746141-34" @default.
- W4316500424 hasPublicationYear "2023" @default.
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