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- W4316591911 endingPage "6722" @default.
- W4316591911 startingPage "6708" @default.
- W4316591911 abstract "Cortical folding patterns are related to brain function, cognition, and behavior. Since the relationship has not been fully explained on a coarse scale, many efforts have been devoted to the identification of finer grained cortical landmarks, such as sulcal pits and gyral peaks, which were found to remain invariant across subjects and ages and the invariance may be related to gene mediated proto-map. However, gyral peaks were only investigated on macaque monkey brains, but not on human brains where the investigation is challenged due to high inter-individual variabilities. To this end, in this work, we successfully identified 96 gyral peaks both on the left and right hemispheres of human brains, respectively. These peaks are spatially consistent across individuals. Higher or sharper peaks are more consistent across subjects. Both structural and functional graph metrics of peaks are significantly different from other cortical regions, and more importantly, these nodal graph metrics are anti-correlated with the spatial consistency metrics within peaks. In addition, the distribution of peaks and various cortical anatomical, structural/functional connective features show hemispheric symmetry. These findings provide new clues to understanding the cortical landmarks, as well as their relationship with brain functions, cognition, behavior in both healthy and aberrant brains." @default.
- W4316591911 created "2023-01-17" @default.
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- W4316591911 creator A5064118534 @default.
- W4316591911 creator A5086402061 @default.
- W4316591911 date "2023-01-16" @default.
- W4316591911 modified "2023-10-16" @default.
- W4316591911 title "Gyral peaks and patterns in human brains" @default.
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