FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4316654901> ?p ?o ?g. }

• W4316654901 endingPage "123281" @default.
• W4316654901 startingPage "123281" @default.
• W4316654901 abstract "Telomeres, which are located at the ends of eukaryotic chromosomes, are crucial for genomic maintenance. Most telomeric DNA is composed of tandemly repeated guanine (G)-rich sequences, which form G-quadruplexes (G4s). The structures and dynamics of telomeric G4s are essential for telomere functioning and helpful for G4-based biosensing. However, they are far from being understood, especially for plants. In this contribution, the folding, environment-induced G4 dynamics, and protein-catalyzed unfolding of plant telomeric G4s were comprehensively studied. It was found that diverse plant telomeric sequences from land plants to green algae could fold into G4 structures. In addition, 5′-proximal ssDNA but not 3′-proximal ssDNA drove conversion of anti-parallel G4 structures to parallel structures, and both 5′ and 3′ ssDNA decreased the stability of G4s in dilute solution. Furthermore, molecular crowding promoted the formation of parallel structures for three-layer but not for two-layer G4s, and increased the stability of all selected G4s. Finally, AtRecQ2 helicase resolved the stable parallel structure of typical plant telomeric G4 in crowded solution, but ssDNA binding protein AtRPA did not. Furthermore, AtRecQ2 unwound the structure more efficiently in the presence of AtRPA. The results may expand our understanding on the structures and dynamics of plant telomeric G4s." @default.
• W4316654901 created "2023-01-17" @default.
• W4316654901 creator A5006651636 @default.
• W4316654901 creator A5026631806 @default.
• W4316654901 creator A5038805449 @default.
• W4316654901 creator A5040534800 @default.
• W4316654901 creator A5072556775 @default.
• W4316654901 creator A5084307208 @default.
• W4316654901 date "2023-03-01" @default.
• W4316654901 modified "2023-09-27" @default.
• W4316654901 title "Comprehensive insights into the structures and dynamics of plant telomeric G-quadruplexes" @default.
• W4316654901 cites W1565365142 @default.
• W4316654901 cites W1829553711 @default.
• W4316654901 cites W1974800636 @default.
• W4316654901 cites W1979505180 @default.
• W4316654901 cites W1981373869 @default.
• W4316654901 cites W1986392710 @default.
• W4316654901 cites W1989739896 @default.
• W4316654901 cites W1998085469 @default.
• W4316654901 cites W1998940503 @default.
• W4316654901 cites W1999247982 @default.
• W4316654901 cites W2007812774 @default.
• W4316654901 cites W2012219231 @default.
• W4316654901 cites W2013588275 @default.
• W4316654901 cites W2015830666 @default.
• W4316654901 cites W2017429695 @default.
• W4316654901 cites W2034997000 @default.
• W4316654901 cites W2038929178 @default.
• W4316654901 cites W2050971157 @default.
• W4316654901 cites W2060017837 @default.
• W4316654901 cites W2061487334 @default.
• W4316654901 cites W2098119559 @default.
• W4316654901 cites W2105543230 @default.
• W4316654901 cites W2131993174 @default.
• W4316654901 cites W2142844453 @default.
• W4316654901 cites W2143861865 @default.
• W4316654901 cites W2162110004 @default.
• W4316654901 cites W2331682169 @default.
• W4316654901 cites W2463040280 @default.
• W4316654901 cites W2524542824 @default.
• W4316654901 cites W2732296396 @default.
• W4316654901 cites W2751625746 @default.
• W4316654901 cites W2895489566 @default.
• W4316654901 cites W2910712381 @default.
• W4316654901 cites W3011066254 @default.
• W4316654901 cites W3017349264 @default.
• W4316654901 cites W3035519481 @default.
• W4316654901 cites W3043116289 @default.
• W4316654901 cites W3048864866 @default.
• W4316654901 cites W3120625911 @default.
• W4316654901 cites W3123384049 @default.
• W4316654901 cites W3144399371 @default.
• W4316654901 cites W3192328034 @default.
• W4316654901 cites W3196885891 @default.
• W4316654901 cites W3217215496 @default.
• W4316654901 cites W4200539932 @default.
• W4316654901 cites W4255306538 @default.
• W4316654901 cites W4283155860 @default.
• W4316654901 cites W4376453542 @default.
• W4316654901 doi "https://doi.org/10.1016/j.ijbiomac.2023.123281" @default.
• W4316654901 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36657543" @default.
• W4316654901 hasPublicationYear "2023" @default.
• W4316654901 type Work @default.
• W4316654901 citedByCount "1" @default.
• W4316654901 countsByYear W43166549012023 @default.
• W4316654901 crossrefType "journal-article" @default.
• W4316654901 hasAuthorship W4316654901A5006651636 @default.
• W4316654901 hasAuthorship W4316654901A5026631806 @default.
• W4316654901 hasAuthorship W4316654901A5038805449 @default.
• W4316654901 hasAuthorship W4316654901A5040534800 @default.
• W4316654901 hasAuthorship W4316654901A5072556775 @default.
• W4316654901 hasAuthorship W4316654901A5084307208 @default.
• W4316654901 hasConcept C104317684 @default.
• W4316654901 hasConcept C119599485 @default.
• W4316654901 hasConcept C12554922 @default.
• W4316654901 hasConcept C127413603 @default.
• W4316654901 hasConcept C161223559 @default.
• W4316654901 hasConcept C177336024 @default.
• W4316654901 hasConcept C185592680 @default.
• W4316654901 hasConcept C2776545253 @default.
• W4316654901 hasConcept C54355233 @default.
• W4316654901 hasConcept C552990157 @default.
• W4316654901 hasConcept C67705224 @default.
• W4316654901 hasConcept C70721500 @default.
• W4316654901 hasConcept C83762044 @default.
• W4316654901 hasConcept C86803240 @default.
• W4316654901 hasConceptScore W4316654901C104317684 @default.
• W4316654901 hasConceptScore W4316654901C119599485 @default.
• W4316654901 hasConceptScore W4316654901C12554922 @default.
• W4316654901 hasConceptScore W4316654901C127413603 @default.
• W4316654901 hasConceptScore W4316654901C161223559 @default.
• W4316654901 hasConceptScore W4316654901C177336024 @default.
• W4316654901 hasConceptScore W4316654901C185592680 @default.
• W4316654901 hasConceptScore W4316654901C2776545253 @default.
• W4316654901 hasConceptScore W4316654901C54355233 @default.
• W4316654901 hasConceptScore W4316654901C552990157 @default.
• W4316654901 hasConceptScore W4316654901C67705224 @default.
• W4316654901 hasConceptScore W4316654901C70721500 @default.

• next