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- W4316664909 abstract "Homocysteine (Hcy) is an intermediate amino acid formed during the conversion from methionine to cysteine. When the fasting plasma Hcy level is higher than 15 μmol/L, it is considered as hyperhomocysteinemia (HHcy). The vascular endothelium is an important barrier to vascular homeostasis, and its impairment is the initiation of atherosclerosis (AS). HHcy is an important risk factor for AS, which can promote the development of AS and the occurrence of cardiovascular events, and Hcy damage to the endothelium is considered to play a very important role. However, the mechanism by which Hcy damages the endothelium is still not fully understood. This review summarizes the mechanism of Hcy-induced endothelial injury and the treatment methods to alleviate the Hcy induced endothelial dysfunction, in order to provide new thoughts for the diagnosis and treatment of Hcy-induced endothelial injury and subsequent AS-related diseases." @default.
- W4316664909 created "2023-01-17" @default.
- W4316664909 creator A5005686824 @default.
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- W4316664909 creator A5051453836 @default.
- W4316664909 creator A5054709496 @default.
- W4316664909 date "2023-01-16" @default.
- W4316664909 modified "2023-10-16" @default.
- W4316664909 title "Mechanism of homocysteine-mediated endothelial injury and its consequences for atherosclerosis" @default.
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