Matches in SemOpenAlex for { <https://semopenalex.org/work/W4316690036> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W4316690036 endingPage "200" @default.
- W4316690036 startingPage "200" @default.
- W4316690036 abstract "Early treatment with antivirals against SARS-CoV-2 infection can prevent the onset of severe COVID-19 in fragile and immunocompromised patients. In this real-life, prospective, observational study, we evaluated efficacy and safety of a 3-day early treatment with remdesivir in adult and fragile patients with a diagnosis of SARS-CoV-2 infection who referred to the COVID-19 early treatment service of Infectious Diseases Unit of University of Naples Federico from 10 January 2022 to 31 March 2022. The included patients could be treated with either remdesivir alone or with remdesivir plus a monoclonal antibody with activity against SARS-CoV-2. Among the 62 included patients, we showed low rates of hospitalization (8%), increase in oxygen supplementation (3.2%), ICU admission (1.6%) and death (1.6%). The rate of disease progression was 8% and it was similar in patients treated with remdesivir alone or in combination with monoclonal antibodies (6.7% and 9.4%, respectively; p = 0.531). The rate of adverse drug reaction was low and similar in the two groups (13.3% in patients treated with remdesivir, 15.6% in patients treated with the combination; p = 0.543). Most common adverse events were headache and fever. In conclusion, in our cohort of patients at a high risk of worse COVID-19 outcomes, an early course of remdesivir showed low rates of disease progression and adverse drug reactions." @default.
- W4316690036 created "2023-01-17" @default.
- W4316690036 creator A5005030383 @default.
- W4316690036 creator A5028266957 @default.
- W4316690036 creator A5031247439 @default.
- W4316690036 creator A5055362865 @default.
- W4316690036 creator A5066109758 @default.
- W4316690036 creator A5071429860 @default.
- W4316690036 creator A5074367003 @default.
- W4316690036 creator A5087979348 @default.
- W4316690036 date "2023-01-17" @default.
- W4316690036 modified "2023-10-02" @default.
- W4316690036 title "Remdesivir Alone or in Combination with Monoclonal Antibodies as an Early Treatment to Prevent Severe COVID-19 in Patients with Mild/Moderate Disease at High Risk of Progression: A Single Centre, Real-Life Study" @default.
- W4316690036 cites W2102263282 @default.
- W4316690036 cites W2150047295 @default.
- W4316690036 cites W2725497285 @default.
- W4316690036 cites W3205344656 @default.
- W4316690036 cites W3212101057 @default.
- W4316690036 cites W4200206478 @default.
- W4316690036 cites W4224315404 @default.
- W4316690036 cites W4225120401 @default.
- W4316690036 cites W4226163566 @default.
- W4316690036 cites W4229036518 @default.
- W4316690036 cites W4283027133 @default.
- W4316690036 cites W4289339206 @default.
- W4316690036 cites W4293248842 @default.
- W4316690036 cites W4294636903 @default.
- W4316690036 cites W4297884493 @default.
- W4316690036 cites W4302763581 @default.
- W4316690036 cites W4306673647 @default.
- W4316690036 cites W4308773341 @default.
- W4316690036 doi "https://doi.org/10.3390/vaccines11020200" @default.
- W4316690036 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36851078" @default.
- W4316690036 hasPublicationYear "2023" @default.
- W4316690036 type Work @default.
- W4316690036 citedByCount "4" @default.
- W4316690036 countsByYear W43166900362023 @default.
- W4316690036 crossrefType "journal-article" @default.
- W4316690036 hasAuthorship W4316690036A5005030383 @default.
- W4316690036 hasAuthorship W4316690036A5028266957 @default.
- W4316690036 hasAuthorship W4316690036A5031247439 @default.
- W4316690036 hasAuthorship W4316690036A5055362865 @default.
- W4316690036 hasAuthorship W4316690036A5066109758 @default.
- W4316690036 hasAuthorship W4316690036A5071429860 @default.
- W4316690036 hasAuthorship W4316690036A5074367003 @default.
- W4316690036 hasAuthorship W4316690036A5087979348 @default.
- W4316690036 hasBestOaLocation W43166900361 @default.
- W4316690036 hasConcept C126322002 @default.
- W4316690036 hasConcept C159654299 @default.
- W4316690036 hasConcept C179755657 @default.
- W4316690036 hasConcept C188816634 @default.
- W4316690036 hasConcept C197934379 @default.
- W4316690036 hasConcept C203014093 @default.
- W4316690036 hasConcept C2779134260 @default.
- W4316690036 hasConcept C542903549 @default.
- W4316690036 hasConcept C71924100 @default.
- W4316690036 hasConceptScore W4316690036C126322002 @default.
- W4316690036 hasConceptScore W4316690036C159654299 @default.
- W4316690036 hasConceptScore W4316690036C179755657 @default.
- W4316690036 hasConceptScore W4316690036C188816634 @default.
- W4316690036 hasConceptScore W4316690036C197934379 @default.
- W4316690036 hasConceptScore W4316690036C203014093 @default.
- W4316690036 hasConceptScore W4316690036C2779134260 @default.
- W4316690036 hasConceptScore W4316690036C542903549 @default.
- W4316690036 hasConceptScore W4316690036C71924100 @default.
- W4316690036 hasIssue "2" @default.
- W4316690036 hasLocation W43166900361 @default.
- W4316690036 hasLocation W43166900362 @default.
- W4316690036 hasLocation W43166900363 @default.
- W4316690036 hasOpenAccess W4316690036 @default.
- W4316690036 hasPrimaryLocation W43166900361 @default.
- W4316690036 hasRelatedWork W1969822711 @default.
- W4316690036 hasRelatedWork W1999686187 @default.
- W4316690036 hasRelatedWork W2019666956 @default.
- W4316690036 hasRelatedWork W2036403810 @default.
- W4316690036 hasRelatedWork W2049834980 @default.
- W4316690036 hasRelatedWork W2063428357 @default.
- W4316690036 hasRelatedWork W2073840950 @default.
- W4316690036 hasRelatedWork W2340284051 @default.
- W4316690036 hasRelatedWork W4211176747 @default.
- W4316690036 hasRelatedWork W4293213287 @default.
- W4316690036 hasVolume "11" @default.
- W4316690036 isParatext "false" @default.
- W4316690036 isRetracted "false" @default.
- W4316690036 workType "article" @default.