FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4317103177> ?p ?o ?g. }

• W4317103177 endingPage "311" @default.
• W4317103177 startingPage "311" @default.
• W4317103177 abstract "Surface modification of magnetic nanoparticles (MNPs) has been reported to play a significant role in determining their interactions with cell membranes. In this research, the interactions between polymer functionalized (chitosan, CHI or diethylamino-ethyl dextran, DEAE-D) Fe3O4 MNPs, pharmaceutical drugs and model cell membranes were investigated by Langmuir isotherms and adsorption measurements. In this study, 1,2-distearoyl-sn-glycerol-3-phosphate (DSPA) phospholipid monolayers were used as cell membrane models. Insertion experiments demonstrate that diclofenac (DCFN) is not absorbed at the air-water interface, whereas triflupromazine (TFPZ) has a MIP (maximum insertion pressure) of 35 m Nm-1. The insertion of composites MNPs:TFPZ or DCFN has larger MIP values, indicating that the MNPs are adsorbed on the monolayer with the drugs. An Fe3O4@CHI:DCFN composite presented an MIP of 39 m Nm-1 and Fe3O4@DEAE-D:DCFN presented an impressive MIP of 67 mNm-1. In the case of TFPZ, the enhancement in the MIP values is also evident, being 42 mNm-1 for Fe3O4@CHI:TFPZ and 40 mNm-1 for Fe3O4@DEAE-D:DCFN composite. All MNPs:drugs composites have MIP values greater than commonly accepted membrane pressure values, indicating that MNPs:drugs can penetrate a cellular membrane. The fact that the composite MNPs:drugs present greater MIP values than separated compounds indicates that polymer-coated MNPs can act as good drug delivery systems." @default.
• W4317103177 created "2023-01-18" @default.
• W4317103177 creator A5010767124 @default.
• W4317103177 creator A5037034047 @default.
• W4317103177 creator A5051371013 @default.
• W4317103177 date "2023-01-17" @default.
• W4317103177 modified "2023-10-06" @default.
• W4317103177 title "Interaction between Pharmaceutical Drugs and Polymer-Coated Fe3O4 Magnetic Nanoparticles with Langmuir Monolayers as Cellular Membrane Models" @default.
• W4317103177 cites W1584191319 @default.
• W4317103177 cites W1809579453 @default.
• W4317103177 cites W1916585354 @default.
• W4317103177 cites W1970894072 @default.
• W4317103177 cites W1978203230 @default.
• W4317103177 cites W1981590052 @default.
• W4317103177 cites W1989341540 @default.
• W4317103177 cites W1992068462 @default.
• W4317103177 cites W1996184118 @default.
• W4317103177 cites W2002372426 @default.
• W4317103177 cites W2015352689 @default.
• W4317103177 cites W2016894545 @default.
• W4317103177 cites W2038871496 @default.
• W4317103177 cites W2042500412 @default.
• W4317103177 cites W2047317522 @default.
• W4317103177 cites W2051513578 @default.
• W4317103177 cites W2075110639 @default.
• W4317103177 cites W2077142078 @default.
• W4317103177 cites W2079346170 @default.
• W4317103177 cites W2084909485 @default.
• W4317103177 cites W2086514756 @default.
• W4317103177 cites W2088050751 @default.
• W4317103177 cites W2091749430 @default.
• W4317103177 cites W2151640043 @default.
• W4317103177 cites W2332618834 @default.
• W4317103177 cites W2414760940 @default.
• W4317103177 cites W2917874360 @default.
• W4317103177 cites W3044305082 @default.
• W4317103177 cites W3183892982 @default.
• W4317103177 cites W3200918100 @default.
• W4317103177 cites W4200032583 @default.
• W4317103177 cites W4221108185 @default.
• W4317103177 cites W4281565194 @default.
• W4317103177 cites W4281719562 @default.
• W4317103177 cites W68401071 @default.
• W4317103177 doi "https://doi.org/10.3390/pharmaceutics15020311" @default.
• W4317103177 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36839633" @default.
• W4317103177 hasPublicationYear "2023" @default.
• W4317103177 type Work @default.
• W4317103177 citedByCount "1" @default.
• W4317103177 countsByYear W43171031772023 @default.
• W4317103177 crossrefType "journal-article" @default.
• W4317103177 hasAuthorship W4317103177A5010767124 @default.
• W4317103177 hasAuthorship W4317103177A5037034047 @default.
• W4317103177 hasAuthorship W4317103177A5051371013 @default.
• W4317103177 hasBestOaLocation W43171031771 @default.
• W4317103177 hasConcept C115958267 @default.
• W4317103177 hasConcept C12143843 @default.
• W4317103177 hasConcept C127413603 @default.
• W4317103177 hasConcept C13965031 @default.
• W4317103177 hasConcept C150394285 @default.
• W4317103177 hasConcept C155672457 @default.
• W4317103177 hasConcept C171250308 @default.
• W4317103177 hasConcept C178790620 @default.
• W4317103177 hasConcept C185592680 @default.
• W4317103177 hasConcept C192562407 @default.
• W4317103177 hasConcept C41625074 @default.
• W4317103177 hasConcept C42360764 @default.
• W4317103177 hasConcept C43617362 @default.
• W4317103177 hasConcept C521977710 @default.
• W4317103177 hasConcept C55493867 @default.
• W4317103177 hasConcept C7070889 @default.
• W4317103177 hasConcept C87023908 @default.
• W4317103177 hasConceptScore W4317103177C115958267 @default.
• W4317103177 hasConceptScore W4317103177C12143843 @default.
• W4317103177 hasConceptScore W4317103177C127413603 @default.
• W4317103177 hasConceptScore W4317103177C13965031 @default.
• W4317103177 hasConceptScore W4317103177C150394285 @default.
• W4317103177 hasConceptScore W4317103177C155672457 @default.
• W4317103177 hasConceptScore W4317103177C171250308 @default.
• W4317103177 hasConceptScore W4317103177C178790620 @default.
• W4317103177 hasConceptScore W4317103177C185592680 @default.
• W4317103177 hasConceptScore W4317103177C192562407 @default.
• W4317103177 hasConceptScore W4317103177C41625074 @default.
• W4317103177 hasConceptScore W4317103177C42360764 @default.
• W4317103177 hasConceptScore W4317103177C43617362 @default.
• W4317103177 hasConceptScore W4317103177C521977710 @default.
• W4317103177 hasConceptScore W4317103177C55493867 @default.
• W4317103177 hasConceptScore W4317103177C7070889 @default.
• W4317103177 hasConceptScore W4317103177C87023908 @default.
• W4317103177 hasIssue "2" @default.
• W4317103177 hasLocation W43171031771 @default.
• W4317103177 hasLocation W43171031772 @default.
• W4317103177 hasLocation W43171031773 @default.
• W4317103177 hasOpenAccess W4317103177 @default.
• W4317103177 hasPrimaryLocation W43171031771 @default.
• W4317103177 hasRelatedWork W2064640816 @default.
• W4317103177 hasRelatedWork W2074692054 @default.
• W4317103177 hasRelatedWork W2389664744 @default.
• W4317103177 hasRelatedWork W2468679678 @default.

• next