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• W4317182363 abstract "Background and Aim: Epidemiological studies concerning the relations between exposure to air pollutants especially in ozone and disability in older adults were limited. Thus, this study aims to investigate the associations between exposure to long-term air pollution and the risk of disability among the community-dwelling older adults. Methods: Study participants were adopted from the third to sixth wave surveys (1996, 1999, 2003 and 2007 year) in Taiwan Longitudinal Study on Aging (TLSA) (n=2241). We estimated 1-year and 2-year exposure window for ozone levels from 1994 to 2007 by using daily concentration data at air quality monitoring stations in the administrative zone of participants’ residences. The status of disability for each participant was evaluated on the activities of daily living scale (ADLs) and instrumental activities of daily living scale (IADLs). Generalized linear mixed models were used to investigate the associations between long-term ozone exposure and disability after adjusting for covariates. Results: We found that long-term (1-year moving average or 2-year moving average) ozone exposure was positively associated with the risk of disability in the elderly. For example, when the average concentration of ozone increased 1 ppb in 1-year exposure window, the risk of disability for ADL scores &#x2265;1 and IADL scores &#x2265;7 in the elders increased 5.4% (OR=1.054, 95% CI:1.022-1.086) and 4.3% (OR=1.043, 95%CI:1.016-1.071), respectively. As compared to quartile 1 (Q1) of 1-year moving average for ozone levels, quartile 4 (Q4) of ozone exposure was significantly associated with the risk of disability for ADL scores &#x2265;1 and IADL scores &#x2265;7 in older adults (OR=1.858, 95% CI:1.404-2.459 for ADL scores &#x2265;1; OR=1.700, 95%CI:1.331-2.171 for IADL scores &#x2265;7). Conclusions: Our results indicated that the long-term exposure to ozone could be a risk factor of disability in older adults. More researches on the biological mechanism of ozone-disability associations are required in the future." @default.
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• W4317182363 date "2022-09-18" @default.
• W4317182363 modified "2023-09-29" @default.
• W4317182363 title "Associations between long-term air pollution exposure and physical function in older adults" @default.
• W4317182363 doi "https://doi.org/10.1289/isee.2022.p-0145" @default.
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