FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4317233606> ?p ?o ?g. }

• W4317233606 endingPage "141502" @default.
• W4317233606 startingPage "141502" @default.
• W4317233606 abstract "The invasion and metastasis of breast cancer are closely related to various biomarkers expressed on the surface of tumor cells and the tumor microenvironment. The deficiency of sensitive phenotypic diagnosis and therapeutic evaluation toward breast cancers represents a significant challenge in cancer diagnosis and therapy. Herein, we report a crucial example of surface-enhanced Raman scattering (SERS)-based imaging utilizing highly sensitive SERS probes to serve as a robust platform for the detection of breast cancer phenotypic biomarkers expressed on the cell surfaces and therapeutic evaluation after chemical therapy and surgery. The SERS probes feature gold-silver (Au@Ag) core–shell nanoparticles with double-layer Raman reporters embedding on the surfaces of the gold core and silver shell, respectively, which further conjugate with specific antibodies. The highly enhanced SERS signals permit the sensitive detection of specific phenotypic biomarkers expressed on the cell surface. In the present work, the epidermal growth factor receptors (EGFR and ErbB2) and insulin-like growth factor 1 (IGF1) were selected as the target biomarkers and assessed the expression in MCF-10A human normal breast cell line and MDA-MB-468, SK-BR-3, KPL-4 human breast cancer cell lines through the SERS-based imaging technique. In the xenotransplanted breast tumor model, systematic delivery of SERS probes enabled precise therapeutic evaluation after anticancer drug tamoxifen therapy and surgery treatment through SERS imaging. Consequently, SERS imaging was consistent with H&E and Masson staining. These results suggest the proposed SERS-based imaging technique has a strong potential to be a powerful tool for precise diagnosis and therapeutic efficacy of breast cancers." @default.
• W4317233606 created "2023-01-18" @default.
• W4317233606 creator A5005745218 @default.
• W4317233606 creator A5009354036 @default.
• W4317233606 creator A5016373392 @default.
• W4317233606 creator A5070812231 @default.
• W4317233606 creator A5076563235 @default.
• W4317233606 creator A5076699095 @default.
• W4317233606 creator A5084484699 @default.
• W4317233606 date "2023-03-01" @default.
• W4317233606 modified "2023-10-16" @default.
• W4317233606 title "Highly sensitive surface-enhanced Raman scattering (SERS) imaging for phenotypic diagnosis and therapeutic evaluation of breast cancer" @default.
• W4317233606 cites W1999435920 @default.
• W4317233606 cites W2021194998 @default.
• W4317233606 cites W2026169053 @default.
• W4317233606 cites W2067287567 @default.
• W4317233606 cites W2103469703 @default.
• W4317233606 cites W2336621323 @default.
• W4317233606 cites W2801860638 @default.
• W4317233606 cites W2885448835 @default.
• W4317233606 cites W2898428288 @default.
• W4317233606 cites W2910085257 @default.
• W4317233606 cites W2919989315 @default.
• W4317233606 cites W2921520311 @default.
• W4317233606 cites W2966338121 @default.
• W4317233606 cites W2973263191 @default.
• W4317233606 cites W2983648113 @default.
• W4317233606 cites W2999681746 @default.
• W4317233606 cites W3010363161 @default.
• W4317233606 cites W3031442866 @default.
• W4317233606 cites W3036882247 @default.
• W4317233606 cites W3040882542 @default.
• W4317233606 cites W3092995259 @default.
• W4317233606 cites W3106876225 @default.
• W4317233606 cites W3135012251 @default.
• W4317233606 cites W3146531007 @default.
• W4317233606 cites W3199766353 @default.
• W4317233606 cites W3209160574 @default.
• W4317233606 cites W4206841660 @default.
• W4317233606 doi "https://doi.org/10.1016/j.cej.2023.141502" @default.
• W4317233606 hasPublicationYear "2023" @default.
• W4317233606 type Work @default.
• W4317233606 citedByCount "6" @default.
• W4317233606 countsByYear W43172336062023 @default.
• W4317233606 crossrefType "journal-article" @default.
• W4317233606 hasAuthorship W4317233606A5005745218 @default.
• W4317233606 hasAuthorship W4317233606A5009354036 @default.
• W4317233606 hasAuthorship W4317233606A5016373392 @default.
• W4317233606 hasAuthorship W4317233606A5070812231 @default.
• W4317233606 hasAuthorship W4317233606A5076563235 @default.
• W4317233606 hasAuthorship W4317233606A5076699095 @default.
• W4317233606 hasAuthorship W4317233606A5084484699 @default.
• W4317233606 hasConcept C121608353 @default.
• W4317233606 hasConcept C126322002 @default.
• W4317233606 hasConcept C134306372 @default.
• W4317233606 hasConcept C142724271 @default.
• W4317233606 hasConcept C1491633281 @default.
• W4317233606 hasConcept C171250308 @default.
• W4317233606 hasConcept C185592680 @default.
• W4317233606 hasConcept C192562407 @default.
• W4317233606 hasConcept C197336794 @default.
• W4317233606 hasConcept C33923547 @default.
• W4317233606 hasConcept C502942594 @default.
• W4317233606 hasConcept C530470458 @default.
• W4317233606 hasConcept C55493867 @default.
• W4317233606 hasConcept C71924100 @default.
• W4317233606 hasConcept C96232424 @default.
• W4317233606 hasConceptScore W4317233606C121608353 @default.
• W4317233606 hasConceptScore W4317233606C126322002 @default.
• W4317233606 hasConceptScore W4317233606C134306372 @default.
• W4317233606 hasConceptScore W4317233606C142724271 @default.
• W4317233606 hasConceptScore W4317233606C1491633281 @default.
• W4317233606 hasConceptScore W4317233606C171250308 @default.
• W4317233606 hasConceptScore W4317233606C185592680 @default.
• W4317233606 hasConceptScore W4317233606C192562407 @default.
• W4317233606 hasConceptScore W4317233606C197336794 @default.
• W4317233606 hasConceptScore W4317233606C33923547 @default.
• W4317233606 hasConceptScore W4317233606C502942594 @default.
• W4317233606 hasConceptScore W4317233606C530470458 @default.
• W4317233606 hasConceptScore W4317233606C55493867 @default.
• W4317233606 hasConceptScore W4317233606C71924100 @default.
• W4317233606 hasConceptScore W4317233606C96232424 @default.
• W4317233606 hasFunder F4320321001 @default.
• W4317233606 hasFunder F4320322866 @default.
• W4317233606 hasLocation W43172336061 @default.
• W4317233606 hasOpenAccess W4317233606 @default.
• W4317233606 hasPrimaryLocation W43172336061 @default.
• W4317233606 hasRelatedWork W1988393794 @default.
• W4317233606 hasRelatedWork W2148948361 @default.
• W4317233606 hasRelatedWork W2378785636 @default.
• W4317233606 hasRelatedWork W2748952813 @default.
• W4317233606 hasRelatedWork W2899084033 @default.
• W4317233606 hasRelatedWork W2949098585 @default.
• W4317233606 hasRelatedWork W2949137069 @default.
• W4317233606 hasRelatedWork W2949574874 @default.
• W4317233606 hasRelatedWork W2953361276 @default.
• W4317233606 hasRelatedWork W4304116770 @default.
• W4317233606 hasVolume "459" @default.

• next