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- W4317241036 abstract "Greece is known for its unique biodiversity, consisting of approximately 6.000 species of higher plants. Of these, ~ 15% of the plant taxa are endemic making Greece an area of high conservation priority [1], [2]. Due to its wealth, there is an increasing interest in the study of the Greek flora, since a great variety of bioactive compounds can be obtained [3]. The aim of this study was to evaluate the chemical content and the biological properties of various plants of the Greek flora for their potential use in cosmeceuticals. 52 plant materials from different areas were selected, collected and extracted using tow techniques i.e., Supercritical Fluid Extraction (SFE) & Accelerated Solvent Extraction (ASE). The chemical profiling of the extracts was performed with LC-HRMS and HPTLC. Dereplication based on high resolution mass spectra gave information about the composition and possible bioactive compounds of the extracts. Furthermore, total phenolic content, antioxidant activity, cytotoxicity and UV-protective activity of the extracts on human skin fibroblast cultures were analyzed. Most extracts (59%) were not cytotoxic for human skin cells, while the rest were used in the photoprotection assay at the highest non-cytotoxic concentration. Until now 10 extracts have been identified combining antioxidant with photoprotective activity. In conclusion, based on the chemical content and in correlation with the biological profile of these extracts, they could serve as an excellent base for the development of novel and high-quality cosmetics." @default.
- W4317241036 created "2023-01-18" @default.
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- W4317241036 date "2022-12-01" @default.
- W4317241036 modified "2023-10-02" @default.
- W4317241036 title "Chemical and biological evaluation of plants from the Greek flora towards their use as cosmetics" @default.
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- W4317241036 doi "https://doi.org/10.1055/s-0042-1759186" @default.
- W4317241036 hasPublicationYear "2022" @default.
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