Matches in SemOpenAlex for { <https://semopenalex.org/work/W4317387685> ?p ?o ?g. }
- W4317387685 abstract "Neurobiological models to explain the vulnerability of autism spectrum disorders (ASDs) are scarce, and previous resting-state functional magnetic resonance imaging (rs-fMRI) studies mostly examined static functional connectivity (FC). Given that FC constantly evolves, it is critical to probe FC dynamic differences in ASD patients.We characterized recurring phase-locking (PL) states during rest in 45 ASD patients and 47 age- and sex-matched healthy controls (HCs) using Leading Eigenvector Dynamics Analysis (LEiDA) and probed the organization of PL states across different fine grain sizes.Our results identified five different groups of discrete resting-state functional networks, which can be defined as recurrent PL state overtimes. Specifically, ASD patients showed an increased probability of three PL states, consisting of the visual network (VIS), frontoparietal control network (FPN), default mode network (DMN), and ventral attention network (VAN). Correspondingly, ASD patients also showed a decreased probability of two PL states, consisting of the subcortical network (SUB), somatomotor network (SMN), FPN, and VAN.Our findings suggested that the temporal reorganization of brain discrete networks was closely linked to sensory to cognitive systems of the brain. Our study provides new insights into the dynamics of brain networks and contributes to a deeper understanding of the neurological mechanisms of ASD." @default.
- W4317387685 created "2023-01-19" @default.
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- W4317387685 date "2023-01-19" @default.
- W4317387685 modified "2023-10-11" @default.
- W4317387685 title "Alteration of resting-state network dynamics in autism spectrum disorder based on leading eigenvector dynamics analysis" @default.
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- W4317387685 doi "https://doi.org/10.3389/fnint.2022.922577" @default.
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