FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4317401629> ?p ?o ?g. }

• W4317401629 endingPage "1867" @default.
• W4317401629 startingPage "1867" @default.
• W4317401629 abstract "Progress in prognostic factors, treatments, and outcome for both canine and human osteosarcoma (OS) has been minimal over the last three decades. Surface overexpression of the cation independent mannose-6-phosphate/insulin-like growth factor receptor type 2 (IGF2R) has been proven to occur in human OS cells. Subsequently, radioimmunotherapy (RIT) targeting IGF2R has demonstrated promising preliminary results. The main aims of this study were to investigate the expression of IGF2R in spontaneously occurring canine OS cells using immunohistochemistry (IHC) on archived biopsy samples and to assess its prognostic significance. Thirty-four dogs were included in the study. All cases showed that 80-100% of OS cells stained positive for IGF2R. IGF2R overexpression alone was not shown to have prognostic significance using both visual and quantitative methods of IHC staining intensity. This study has established for the first time the consistent expression of IGF2R in spontaneously occurring canine OS. This comparative oncology approach will allow further investigation into RIT as a novel treatment modality; first in canines and then in humans with OS. In addition, further studies should be performed to assess the true prognostic significance of IGF2R overexpression." @default.
• W4317401629 created "2023-01-19" @default.
• W4317401629 creator A5029817662 @default.
• W4317401629 creator A5034610205 @default.
• W4317401629 creator A5051878746 @default.
• W4317401629 creator A5072265847 @default.
• W4317401629 creator A5076184894 @default.
• W4317401629 date "2023-01-18" @default.
• W4317401629 modified "2023-09-27" @default.
• W4317401629 title "Characterization of IGF2R Molecular Expression in Canine Osteosarcoma as Part of a Novel Comparative Oncology Approach" @default.
• W4317401629 cites W1533229981 @default.
• W4317401629 cites W1537369538 @default.
• W4317401629 cites W15820283 @default.
• W4317401629 cites W1846243321 @default.
• W4317401629 cites W1988325237 @default.
• W4317401629 cites W1996623338 @default.
• W4317401629 cites W2013243402 @default.
• W4317401629 cites W2014625042 @default.
• W4317401629 cites W2014931987 @default.
• W4317401629 cites W2017624163 @default.
• W4317401629 cites W2034924732 @default.
• W4317401629 cites W2065109604 @default.
• W4317401629 cites W2076693259 @default.
• W4317401629 cites W2080464382 @default.
• W4317401629 cites W2082829529 @default.
• W4317401629 cites W2082957304 @default.
• W4317401629 cites W2083485224 @default.
• W4317401629 cites W2090928430 @default.
• W4317401629 cites W2101871646 @default.
• W4317401629 cites W2110835296 @default.
• W4317401629 cites W2121448551 @default.
• W4317401629 cites W2133038691 @default.
• W4317401629 cites W2136388877 @default.
• W4317401629 cites W2152535349 @default.
• W4317401629 cites W2153466352 @default.
• W4317401629 cites W2169798600 @default.
• W4317401629 cites W2443643663 @default.
• W4317401629 cites W2477396450 @default.
• W4317401629 cites W2485196708 @default.
• W4317401629 cites W2535143162 @default.
• W4317401629 cites W2611196734 @default.
• W4317401629 cites W2767053399 @default.
• W4317401629 cites W2779195657 @default.
• W4317401629 cites W28828729 @default.
• W4317401629 cites W2900200703 @default.
• W4317401629 cites W2915008308 @default.
• W4317401629 cites W2944006666 @default.
• W4317401629 cites W2966618257 @default.
• W4317401629 cites W2969591903 @default.
• W4317401629 cites W2973512921 @default.
• W4317401629 cites W2975192730 @default.
• W4317401629 cites W3004109878 @default.
• W4317401629 cites W3015392591 @default.
• W4317401629 cites W4232229198 @default.
• W4317401629 doi "https://doi.org/10.3390/ijms24031867" @default.
• W4317401629 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36768202" @default.
• W4317401629 hasPublicationYear "2023" @default.
• W4317401629 type Work @default.
• W4317401629 citedByCount "1" @default.
• W4317401629 countsByYear W43174016292023 @default.
• W4317401629 crossrefType "journal-article" @default.
• W4317401629 hasAuthorship W4317401629A5029817662 @default.
• W4317401629 hasAuthorship W4317401629A5034610205 @default.
• W4317401629 hasAuthorship W4317401629A5051878746 @default.
• W4317401629 hasAuthorship W4317401629A5072265847 @default.
• W4317401629 hasAuthorship W4317401629A5076184894 @default.
• W4317401629 hasBestOaLocation W43174016291 @default.
• W4317401629 hasConcept C126322002 @default.
• W4317401629 hasConcept C142724271 @default.
• W4317401629 hasConcept C143998085 @default.
• W4317401629 hasConcept C144174609 @default.
• W4317401629 hasConcept C170493617 @default.
• W4317401629 hasConcept C204232928 @default.
• W4317401629 hasConcept C21936154 @default.
• W4317401629 hasConcept C2775934546 @default.
• W4317401629 hasConcept C2775960820 @default.
• W4317401629 hasConcept C2777760704 @default.
• W4317401629 hasConcept C502942594 @default.
• W4317401629 hasConcept C63363279 @default.
• W4317401629 hasConcept C71924100 @default.
• W4317401629 hasConceptScore W4317401629C126322002 @default.
• W4317401629 hasConceptScore W4317401629C142724271 @default.
• W4317401629 hasConceptScore W4317401629C143998085 @default.
• W4317401629 hasConceptScore W4317401629C144174609 @default.
• W4317401629 hasConceptScore W4317401629C170493617 @default.
• W4317401629 hasConceptScore W4317401629C204232928 @default.
• W4317401629 hasConceptScore W4317401629C21936154 @default.
• W4317401629 hasConceptScore W4317401629C2775934546 @default.
• W4317401629 hasConceptScore W4317401629C2775960820 @default.
• W4317401629 hasConceptScore W4317401629C2777760704 @default.
• W4317401629 hasConceptScore W4317401629C502942594 @default.
• W4317401629 hasConceptScore W4317401629C63363279 @default.
• W4317401629 hasConceptScore W4317401629C71924100 @default.
• W4317401629 hasIssue "3" @default.
• W4317401629 hasLocation W43174016291 @default.
• W4317401629 hasLocation W43174016292 @default.
• W4317401629 hasLocation W43174016293 @default.
• W4317401629 hasOpenAccess W4317401629 @default.

• next