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• W4317434657 abstract "Organ failure (OF) and death are considered the most significant adverse outcomes in necrotizing pancreatitis (NP). However, there are few NP-related studies describing the clinical traits of OF and aggravated outcomes.An improved insight into the details of OF and death will be helpful to the management of NP. Thus, in our research, we addressed the risk factors of OF and death in NP patients.We performed a study of 432 NP patients from May 2017 to December 2021. All patients with NP were followed up for 36 months. The primary end-points were risk factors of OF and death in NP patients. The risk factors were evaluated by logistic regression analysis.NP patients with OF or death patients were generally older, had a higher APACHE II score, longer hospital stay, longer ICU stay, as well as a higher incidence of severe acute pancreatitis (SAP), shock and pancreatic necrosis. Independent risk factors related to OF included BMI, APACHE II score and SAP (P < 0.05). Age, shock and APACHE II score (P < 0.05) were the most significant factors correlated with the risk of death in NP patients. Notably, increased mortality was linked to the number of failed organs.NP is a potentially fatal disease with a long hospital or ICU stay. Our study indicated that the incidence of OF and death in NP patients was 69.9% and 10.2%, respectively. BMI, SAP, APACHE II score, age and shock are potential risk factors of OF and death in NP patients. Clinicians should focus on these factors for early diagnosis and appropriate therapy." @default.
• W4317434657 created "2023-01-19" @default.
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• W4317434657 date "2023-01-19" @default.
• W4317434657 modified "2023-10-18" @default.
• W4317434657 title "Clinical characteristics and risk factors of organ failure and death in necrotizing pancreatitis" @default.
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• W4317434657 doi "https://doi.org/10.1186/s12876-023-02651-4" @default.
• W4317434657 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36658497" @default.
• W4317434657 hasPublicationYear "2023" @default.
• W4317434657 type Work @default.

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