Matches in SemOpenAlex for { <https://semopenalex.org/work/W4317436730> ?p ?o ?g. }
- W4317436730 abstract "During a radiological or nuclear public health emergency, given the heterogeneity of civilian populations, it is incumbent on medical response planners to understand and prepare for a potentially high degree of interindividual variability in the biological effects of radiation exposure. A part of advanced planning should include a comprehensive approach, in which the range of possible human responses in relation to the type of radiation expected from an incident has been thoughtfully considered. Although there are several reports addressing the radiation response for special populations (as compared to the standard 18–45-year-old male), the current review surveys published literature to assess the level of consideration given to differences in acute radiation responses in certain sub-groups. The authors attempt to bring clarity to the complex nature of human biology in the context of radiation to facilitate a path forward for radiation medical countermeasure (MCM) development that may be appropriate and effective in special populations. Consequently, the focus is on the medical (as opposed to logistical) aspects of preparedness and response. Populations identified for consideration include obstetric, pediatric, geriatric, males, females, individuals of different race/ethnicity, and people with comorbidities. Relevant animal models, biomarkers of radiation injury, and MCMs are highlighted, in addition to underscoring gaps in knowledge and the need for consistent and early inclusion of these populations in research. The inclusion of special populations in preclinical and clinical studies is essential to address shortcomings and is an important consideration for radiation public health emergency response planning. Pursuing this goal will benefit the population at large by considering those at greatest risk of health consequences after a radiological or nuclear mass casualty incident." @default.
- W4317436730 created "2023-01-19" @default.
- W4317436730 creator A5004865513 @default.
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- W4317436730 date "2023-01-17" @default.
- W4317436730 modified "2023-09-27" @default.
- W4317436730 title "Considerations of Medical Preparedness to Assess and Treat Various Populations During a Radiation Public Health Emergency" @default.
- W4317436730 cites W132518952 @default.
- W4317436730 cites W137087168 @default.
- W4317436730 cites W1484334610 @default.
- W4317436730 cites W1505906622 @default.
- W4317436730 cites W1523685166 @default.
- W4317436730 cites W1551102474 @default.
- W4317436730 cites W1677086045 @default.
- W4317436730 cites W1844637553 @default.
- W4317436730 cites W1845218026 @default.
- W4317436730 cites W184678588 @default.
- W4317436730 cites W1884290625 @default.
- W4317436730 cites W1888220018 @default.
- W4317436730 cites W1900458424 @default.
- W4317436730 cites W1914345907 @default.
- W4317436730 cites W1964216862 @default.
- W4317436730 cites W1964293607 @default.
- W4317436730 cites W1964335566 @default.
- W4317436730 cites W1965671693 @default.
- W4317436730 cites W1966132436 @default.
- W4317436730 cites W1966655498 @default.
- W4317436730 cites W1971028546 @default.
- W4317436730 cites W1974642822 @default.
- W4317436730 cites W1979281993 @default.
- W4317436730 cites W1982199188 @default.
- W4317436730 cites W1982905750 @default.
- W4317436730 cites W1983763746 @default.
- W4317436730 cites W1988001018 @default.
- W4317436730 cites W1988820750 @default.
- W4317436730 cites W1991597137 @default.
- W4317436730 cites W1995231361 @default.
- W4317436730 cites W1998243787 @default.
- W4317436730 cites W1998819758 @default.
- W4317436730 cites W2002664587 @default.
- W4317436730 cites W2002812377 @default.
- W4317436730 cites W2006426441 @default.
- W4317436730 cites W2007587451 @default.
- W4317436730 cites W200905945 @default.
- W4317436730 cites W2015691715 @default.
- W4317436730 cites W2017866566 @default.
- W4317436730 cites W2022763099 @default.
- W4317436730 cites W2024719775 @default.
- W4317436730 cites W2025200024 @default.
- W4317436730 cites W2025275475 @default.
- W4317436730 cites W2027616883 @default.
- W4317436730 cites W2032594449 @default.
- W4317436730 cites W2038170180 @default.
- W4317436730 cites W2039418530 @default.
- W4317436730 cites W2043122396 @default.
- W4317436730 cites W2043527236 @default.
- W4317436730 cites W2047115656 @default.
- W4317436730 cites W2047310043 @default.
- W4317436730 cites W2047313692 @default.
- W4317436730 cites W2048743639 @default.
- W4317436730 cites W2052500974 @default.
- W4317436730 cites W2054803544 @default.
- W4317436730 cites W2055913006 @default.
- W4317436730 cites W2057487406 @default.
- W4317436730 cites W2057493135 @default.
- W4317436730 cites W2059843925 @default.
- W4317436730 cites W2061248797 @default.
- W4317436730 cites W2061462481 @default.
- W4317436730 cites W2063549676 @default.
- W4317436730 cites W2065344333 @default.
- W4317436730 cites W2065796038 @default.
- W4317436730 cites W2066664467 @default.
- W4317436730 cites W2067052441 @default.
- W4317436730 cites W2069383559 @default.
- W4317436730 cites W2070797273 @default.
- W4317436730 cites W2079426778 @default.
- W4317436730 cites W2081403346 @default.
- W4317436730 cites W2083030274 @default.
- W4317436730 cites W2086736591 @default.
- W4317436730 cites W2090129236 @default.
- W4317436730 cites W2090258038 @default.
- W4317436730 cites W2093263999 @default.
- W4317436730 cites W2093595780 @default.
- W4317436730 cites W2094411201 @default.
- W4317436730 cites W2097583590 @default.
- W4317436730 cites W2100018419 @default.
- W4317436730 cites W2103145789 @default.
- W4317436730 cites W2103269176 @default.
- W4317436730 cites W2109562219 @default.
- W4317436730 cites W2110646546 @default.
- W4317436730 cites W2111858830 @default.
- W4317436730 cites W2121109679 @default.
- W4317436730 cites W2125924455 @default.
- W4317436730 cites W2126707055 @default.