Matches in SemOpenAlex for { <https://semopenalex.org/work/W4317469312> ?p ?o ?g. }
- W4317469312 abstract "Ferroptosis is a non-apoptotic programmed cell death caused by the accumulation of lipid peroxide. System Xc-/glutathione peroxidase 4 (GPX4) axis and iron axis are two main pathways regulating ferroptosis. Simultaneously, multiple pathways are also involved in the ferroptosis regulation. Ferroptosis is an intense area of the current study. With the improvement of the regulatory mechanisms that underlie ferroptosis, a variety of drugs associated with ferroptosis have been discovered and developed for cancer therapy. Among them, traditional drugs were developed initially. Small molecule compounds that regulate ferroptosis signaling pathway and iron complexes that promote the Fenton reaction have become important drugs for inducing ferroptosis. In recent years, the emerging development of nanotechnology has promoted the research of ferroptosis nanodrugs. Iron-based nanomaterials are extensively tested as ferroptosis-inducing agents. Furthermore, nanoscale drug delivery systems offer a suitable scaffold for traditional drug therapies. Traditional drugs and nanodrugs are complementary, each with their own strengths and limitations. This review describes the latest studies on the regulation of ferroptosis in tumor cells and focuses on the entanglement between traditional drugs and nanodrugs. To conclude, the challenges and perspectives in this field are put forward." @default.
- W4317469312 created "2023-01-20" @default.
- W4317469312 creator A5000300207 @default.
- W4317469312 creator A5004707970 @default.
- W4317469312 creator A5016229265 @default.
- W4317469312 creator A5020579375 @default.
- W4317469312 creator A5038215502 @default.
- W4317469312 creator A5039637336 @default.
- W4317469312 creator A5072181731 @default.
- W4317469312 creator A5073568638 @default.
- W4317469312 creator A5083993843 @default.
- W4317469312 creator A5086726959 @default.
- W4317469312 creator A5088470526 @default.
- W4317469312 creator A5089431699 @default.
- W4317469312 date "2023-02-03" @default.
- W4317469312 modified "2023-10-16" @default.
- W4317469312 title "Ferroptosis: The Entanglement between Traditional Drugs and Nanodrugs in Tumor Therapy" @default.
- W4317469312 cites W1147074327 @default.
- W4317469312 cites W1513392008 @default.
- W4317469312 cites W1680841355 @default.
- W4317469312 cites W1979069114 @default.
- W4317469312 cites W1989230986 @default.
- W4317469312 cites W1992816755 @default.
- W4317469312 cites W1996128705 @default.
- W4317469312 cites W1996152690 @default.
- W4317469312 cites W1997183854 @default.
- W4317469312 cites W1997445806 @default.
- W4317469312 cites W1999409505 @default.
- W4317469312 cites W2000737166 @default.
- W4317469312 cites W2007794772 @default.
- W4317469312 cites W2010278922 @default.
- W4317469312 cites W2025531782 @default.
- W4317469312 cites W2027176542 @default.
- W4317469312 cites W2034432182 @default.
- W4317469312 cites W2035898183 @default.
- W4317469312 cites W2042218168 @default.
- W4317469312 cites W2043043757 @default.
- W4317469312 cites W2057632732 @default.
- W4317469312 cites W2060070314 @default.
- W4317469312 cites W2060552903 @default.
- W4317469312 cites W2064094968 @default.
- W4317469312 cites W2068193883 @default.
- W4317469312 cites W2075630515 @default.
- W4317469312 cites W2075856547 @default.
- W4317469312 cites W2083790799 @default.
- W4317469312 cites W2088055025 @default.
- W4317469312 cites W2096294661 @default.
- W4317469312 cites W2101562875 @default.
- W4317469312 cites W2106180867 @default.
- W4317469312 cites W2110383454 @default.
- W4317469312 cites W2111662054 @default.
- W4317469312 cites W2124736536 @default.
- W4317469312 cites W2126695283 @default.
- W4317469312 cites W2137749199 @default.
- W4317469312 cites W2140333474 @default.
- W4317469312 cites W2141958178 @default.
- W4317469312 cites W2155162140 @default.
- W4317469312 cites W2163005196 @default.
- W4317469312 cites W2163294546 @default.
- W4317469312 cites W2234023838 @default.
- W4317469312 cites W2328421677 @default.
- W4317469312 cites W2340375325 @default.
- W4317469312 cites W2362684152 @default.
- W4317469312 cites W2418439210 @default.
- W4317469312 cites W2432913624 @default.
- W4317469312 cites W2470692786 @default.
- W4317469312 cites W2488521558 @default.
- W4317469312 cites W2503056681 @default.
- W4317469312 cites W2519661407 @default.
- W4317469312 cites W2549428458 @default.
- W4317469312 cites W2554773181 @default.
- W4317469312 cites W2560120193 @default.
- W4317469312 cites W2566407837 @default.
- W4317469312 cites W2591580144 @default.
- W4317469312 cites W2593371615 @default.
- W4317469312 cites W2601818643 @default.
- W4317469312 cites W2625568509 @default.
- W4317469312 cites W2751075893 @default.
- W4317469312 cites W2754691860 @default.
- W4317469312 cites W2762087180 @default.
- W4317469312 cites W2772770615 @default.
- W4317469312 cites W2784850597 @default.
- W4317469312 cites W2787460561 @default.
- W4317469312 cites W2793195158 @default.
- W4317469312 cites W2804789540 @default.
- W4317469312 cites W2809820903 @default.
- W4317469312 cites W2810911780 @default.
- W4317469312 cites W2883440571 @default.
- W4317469312 cites W2885626583 @default.
- W4317469312 cites W2890668604 @default.
- W4317469312 cites W2897111276 @default.
- W4317469312 cites W2899366602 @default.
- W4317469312 cites W2900562812 @default.
- W4317469312 cites W2902345528 @default.
- W4317469312 cites W2902635070 @default.
- W4317469312 cites W2904107490 @default.
- W4317469312 cites W2904310948 @default.
- W4317469312 cites W2905891236 @default.
- W4317469312 cites W2912225873 @default.
- W4317469312 cites W2918774140 @default.