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- W4317495536 abstract "Abstract A new, efficient process for the synthesis of 5-acetyl-1H-pyrazole-3-carboxylic acid, a versatile building block and the key intermediate of darolutamide, using diethyl pyrazole-3,5-dicarboxylate as the starting material is described. Contrary to the synthetic routes known from the literature, this procedure does not employ explosive diazo reagents, moreover it is simple and safe, thereby suitable for scale-up." @default.
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- W4317495536 date "2023-01-19" @default.
- W4317495536 modified "2023-09-28" @default.
- W4317495536 title "New, Scalable Process for the Preparation of 5-Acetyl-1H-pyrazole-3-carboxylic Acid, a Key Intermediate of Darolutamide" @default.
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- W4317495536 doi "https://doi.org/10.1055/a-2016-4337" @default.
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