Matches in SemOpenAlex for { <https://semopenalex.org/work/W4317509937> ?p ?o ?g. }
- W4317509937 abstract "The basolateral amygdala (BLA) projects widely across the macaque frontal cortex 1â€4 , and amygdalo-frontal projections are critical for optimal emotional responding 5 and decision- making 6 . Yet, little is known about the single-neuron architecture of these projections: namely, whether single BLA neurons project to multiple parts of the frontal cortex. Here, we use MAPseq 7 to determine the projection patterns of over 3000 macaque BLA neurons. We found that one-third of BLA neurons have two or more distinct targets in parts of frontal cortex and of subcortical structures. Further, we reveal non-random structure within these branching patterns such that neurons with four targets are more frequently observed than those with two or three, indicative of widespread networks. Consequently, these multi-target single neurons form distinct networks within medial and ventral frontal cortex consistent with their known functions in regulating mood and decision-making. Additionally, we show that branching patterns of single neurons shape functional networks in the brain as assessed by fMRI-based functional connectivity. These results provide a neuroanatomical basis for the role of the BLA in coordinating brain-wide responses to valent stimuli 8 and highlight the importance of high- resolution neuroanatomical data for understanding functional networks in the brain." @default.
- W4317509937 created "2023-01-20" @default.
- W4317509937 creator A5002488201 @default.
- W4317509937 creator A5037156084 @default.
- W4317509937 creator A5048816474 @default.
- W4317509937 creator A5061439029 @default.
- W4317509937 creator A5064514761 @default.
- W4317509937 creator A5071883163 @default.
- W4317509937 creator A5073037534 @default.
- W4317509937 creator A5078153359 @default.
- W4317509937 creator A5079934156 @default.
- W4317509937 creator A5083348658 @default.
- W4317509937 creator A5088493359 @default.
- W4317509937 creator A5088568944 @default.
- W4317509937 date "2023-01-18" @default.
- W4317509937 modified "2023-09-26" @default.
- W4317509937 title "High-throughput sequencing of macaque basolateral amygdala projections reveals dissociable connectional motifs with frontal cortex" @default.
- W4317509937 cites W1644117706 @default.
- W4317509937 cites W1912705418 @default.
- W4317509937 cites W1968426398 @default.
- W4317509937 cites W1980208993 @default.
- W4317509937 cites W1985640311 @default.
- W4317509937 cites W1985926085 @default.
- W4317509937 cites W1989146829 @default.
- W4317509937 cites W2001362807 @default.
- W4317509937 cites W2009140566 @default.
- W4317509937 cites W2011301426 @default.
- W4317509937 cites W2019721102 @default.
- W4317509937 cites W2026148432 @default.
- W4317509937 cites W2035157005 @default.
- W4317509937 cites W2047647374 @default.
- W4317509937 cites W2051022103 @default.
- W4317509937 cites W2051492823 @default.
- W4317509937 cites W2063535919 @default.
- W4317509937 cites W2064029491 @default.
- W4317509937 cites W2083227438 @default.
- W4317509937 cites W2095491050 @default.
- W4317509937 cites W2099540110 @default.
- W4317509937 cites W2099925882 @default.
- W4317509937 cites W2111405228 @default.
- W4317509937 cites W2117140276 @default.
- W4317509937 cites W2136550122 @default.
- W4317509937 cites W2137940356 @default.
- W4317509937 cites W2144820951 @default.
- W4317509937 cites W2163324289 @default.
- W4317509937 cites W2343530744 @default.
- W4317509937 cites W2442982730 @default.
- W4317509937 cites W2511999769 @default.
- W4317509937 cites W2514222651 @default.
- W4317509937 cites W2517512733 @default.
- W4317509937 cites W2555223929 @default.
- W4317509937 cites W2582441147 @default.
- W4317509937 cites W2611279297 @default.
- W4317509937 cites W2750722402 @default.
- W4317509937 cites W2766156421 @default.
- W4317509937 cites W2768172955 @default.
- W4317509937 cites W2769583531 @default.
- W4317509937 cites W2793627907 @default.
- W4317509937 cites W2794495549 @default.
- W4317509937 cites W2810326940 @default.
- W4317509937 cites W2895795340 @default.
- W4317509937 cites W2949721578 @default.
- W4317509937 cites W2969343193 @default.
- W4317509937 cites W2980964315 @default.
- W4317509937 cites W2998887651 @default.
- W4317509937 cites W3008186910 @default.
- W4317509937 cites W3038145748 @default.
- W4317509937 cites W3086890576 @default.
- W4317509937 cites W3093545820 @default.
- W4317509937 cites W3099878876 @default.
- W4317509937 cites W3142292409 @default.
- W4317509937 cites W3150635270 @default.
- W4317509937 cites W3151226150 @default.
- W4317509937 cites W3181049527 @default.
- W4317509937 cites W3196227570 @default.
- W4317509937 cites W3202828119 @default.
- W4317509937 cites W3217235049 @default.
- W4317509937 cites W4229023317 @default.
- W4317509937 cites W4250233253 @default.
- W4317509937 cites W4281647591 @default.
- W4317509937 cites W4282943841 @default.
- W4317509937 doi "https://doi.org/10.1101/2023.01.18.524407" @default.
- W4317509937 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36711708" @default.
- W4317509937 hasPublicationYear "2023" @default.
- W4317509937 type Work @default.
- W4317509937 citedByCount "2" @default.
- W4317509937 countsByYear W43175099372023 @default.
- W4317509937 crossrefType "posted-content" @default.
- W4317509937 hasAuthorship W4317509937A5002488201 @default.
- W4317509937 hasAuthorship W4317509937A5037156084 @default.
- W4317509937 hasAuthorship W4317509937A5048816474 @default.
- W4317509937 hasAuthorship W4317509937A5061439029 @default.
- W4317509937 hasAuthorship W4317509937A5064514761 @default.
- W4317509937 hasAuthorship W4317509937A5071883163 @default.
- W4317509937 hasAuthorship W4317509937A5073037534 @default.
- W4317509937 hasAuthorship W4317509937A5078153359 @default.
- W4317509937 hasAuthorship W4317509937A5079934156 @default.
- W4317509937 hasAuthorship W4317509937A5083348658 @default.
- W4317509937 hasAuthorship W4317509937A5088493359 @default.
- W4317509937 hasAuthorship W4317509937A5088568944 @default.