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- W4317526172 abstract "18F-fluorocholine (FCH) has been used as a positron emission tomography (PET) tracer in the localization of hyper-functioning parathyroid glands (HPGs).We performed this methodological study to evaluate the diagnostic performance of 18F-FCH PET/computerized tomography (CT) and repeated ultrasonography (USG) in detecting unidentified lesions in patients with primary hyperparathyroidism (PHPT).In this retrospective methodological study, we studied the diagnostic performance of 18F-FCH PET/CT and a repeated USG in detecting unidentified parathyroid lesions.Twenty-eight patients who were diagnosed with PHPT, had an indication for surgery following the current guidelines and had no identified lesion on 99mTc-MIBI SPECT/CT, USG, or other imaging methods than 18F-FCH PET/CT, included in the study.While lesions were detected in 26 patients via 18F-FCH PET/CT among 28 patients [92.9% (95% CI: 76.6%-99.1%)], the lesion detection rate was 95.7% (95% CI: 78.1%-99.9%) in 23 patients who underwent a repeated USG. The sensitivity and the accuracy of both 18F-FCH PET/CT and repeated USG were 95.2% (95% CI: 76.2%-99.9%) and 95.0 (95% CI: 75.1%-99.9%), respectively.This study supports that the combination of 18F-FCH PET/CT and repeated USG has promising potential for being an imaging technique for early detection and localization of HPGs." @default.
- W4317526172 created "2023-01-20" @default.
- W4317526172 creator A5033180451 @default.
- W4317526172 date "2022-01-01" @default.
- W4317526172 modified "2023-09-26" @default.
- W4317526172 title "Diagnostic Performances of 18f-Fluorocholine Positron Emission Tomography-Computed Tomography and Repeated Ultrasonography in Detecting Undefined Lesions in Patients with an Indication For Primary Hyperparathyroidism Surgery" @default.
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- W4317526172 doi "https://doi.org/10.4183/aeb.2022.316" @default.
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