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- W4317527495 abstract "ABSTRACT. During the years 1975–77, 35 patients with haemophilia A or B (factor level of 1% or less) were instructed to administer concentrates of the deficient factor (mean dose 14 U/kg) i.v. in case of episodic, uncomplicated bleedings without prior consultation with a physician. At Dec. 1977, 33 of these patients (29 with haemophilia A, 4 with B) were taking part in the program. They represent 35% of all Norwegian patients above 7 years of age with severe haemophilia in whom high‐titered antibodies have not been demonstrated. For 13 patients, records from 2 years on self‐therapy have been compared with records from the last year before self‐therapy. During the first year on self‐therapy the number of days lost from work dropped by 77%, while the number of transfusions increased by 22%. During the second year, days lost from work were still low (68% decrease compared to the year preceding self‐therapy) and the transfusion frequency remained unchanged. Significant side‐effects of antihaemophilic concentrates were not observed and vein damage was not a problem. Joint motion studies did not indicate progress of haemophilic arthropathy during self‐therapy. Properly supervised self‐therapy is practical and safe and improves considerably the quality of life." @default.
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- W4317527495 date "1979-01-12" @default.
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- W4317527495 title "Self-Therapy for Haemophilia in Norway." @default.
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- W4317527495 doi "https://doi.org/10.1111/j.0954-6820.1979.tb06071.x" @default.
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