Matches in SemOpenAlex for { <https://semopenalex.org/work/W4317535712> ?p ?o ?g. }
- W4317535712 endingPage "114" @default.
- W4317535712 startingPage "104" @default.
- W4317535712 abstract "Abstract Anti‐seizure medications (ASMs) can cause cognitive or behavioral adverse drug reactions, which is an important consideration when selecting an appropriate ASM. Brivaracetam (BRV) is a newer synaptic vesicle protein 2A ligand, which is expected to result in fewer neuropsychiatric adverse effects due to its mechanism of action. To understand the impact of BRV on cognition and behavior compared with other ASMs, we conducted a review of the literature using the Cochrane Library, PubMed/MEDLINE, and Embase. After the screening process, a total of two animal studies, one randomized controlled trial, one pooled analysis of clinical trials, one controlled study, and nine observational studies were included. The animal studies showed that BRV did not worsen cognitive or behavioral performance in rodents. The human studies showed that BRV was associated with fewer cognitive adverse events compared with other second‐ or third‐generation ASMs. In addition, BRV was less associated with behavioral disturbance than levetiracetam. In summary, this review revealed that BRV has a limited impact on cognition and behavior. For patients who are intolerant to levetiracetam and have levetiracetam‐related behavioral side effects, switching to BRV could be beneficial. However, heterogeneity between studies resulted in low‐quality of evidence, and further trials are needed to confirm the findings." @default.
- W4317535712 created "2023-01-20" @default.
- W4317535712 creator A5027947039 @default.
- W4317535712 creator A5070263915 @default.
- W4317535712 creator A5073576166 @default.
- W4317535712 date "2023-01-20" @default.
- W4317535712 modified "2023-10-02" @default.
- W4317535712 title "A review of cognitive and behavioral outcomes of Brivaracetam" @default.
- W4317535712 cites W1584825281 @default.
- W4317535712 cites W16434660 @default.
- W4317535712 cites W1966931416 @default.
- W4317535712 cites W1988932597 @default.
- W4317535712 cites W1996183804 @default.
- W4317535712 cites W2006459120 @default.
- W4317535712 cites W2019178697 @default.
- W4317535712 cites W2040009475 @default.
- W4317535712 cites W2051958372 @default.
- W4317535712 cites W2069534738 @default.
- W4317535712 cites W2079628500 @default.
- W4317535712 cites W2086336037 @default.
- W4317535712 cites W2099690974 @default.
- W4317535712 cites W2120143658 @default.
- W4317535712 cites W2122573606 @default.
- W4317535712 cites W2150483421 @default.
- W4317535712 cites W2153095386 @default.
- W4317535712 cites W2154460231 @default.
- W4317535712 cites W2157185056 @default.
- W4317535712 cites W2162230460 @default.
- W4317535712 cites W2166281097 @default.
- W4317535712 cites W2168312889 @default.
- W4317535712 cites W2169855442 @default.
- W4317535712 cites W2180981774 @default.
- W4317535712 cites W2200772687 @default.
- W4317535712 cites W2284268250 @default.
- W4317535712 cites W2301815399 @default.
- W4317535712 cites W2323557934 @default.
- W4317535712 cites W2407710406 @default.
- W4317535712 cites W2419659369 @default.
- W4317535712 cites W2472978162 @default.
- W4317535712 cites W2531269403 @default.
- W4317535712 cites W2539233923 @default.
- W4317535712 cites W2555549685 @default.
- W4317535712 cites W2597380388 @default.
- W4317535712 cites W2613020156 @default.
- W4317535712 cites W2747913934 @default.
- W4317535712 cites W2754524371 @default.
- W4317535712 cites W2772130338 @default.
- W4317535712 cites W2776129666 @default.
- W4317535712 cites W2790413540 @default.
- W4317535712 cites W2835221766 @default.
- W4317535712 cites W2883620991 @default.
- W4317535712 cites W2893748822 @default.
- W4317535712 cites W2899343559 @default.
- W4317535712 cites W2900895191 @default.
- W4317535712 cites W2903035030 @default.
- W4317535712 cites W2913866139 @default.
- W4317535712 cites W2922617182 @default.
- W4317535712 cites W2943788532 @default.
- W4317535712 cites W2949905319 @default.
- W4317535712 cites W2972058712 @default.
- W4317535712 cites W2997938254 @default.
- W4317535712 cites W3019350884 @default.
- W4317535712 cites W3022903699 @default.
- W4317535712 doi "https://doi.org/10.1002/kjm2.12648" @default.
- W4317535712 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36661137" @default.
- W4317535712 hasPublicationYear "2023" @default.
- W4317535712 type Work @default.
- W4317535712 citedByCount "0" @default.
- W4317535712 crossrefType "journal-article" @default.
- W4317535712 hasAuthorship W4317535712A5027947039 @default.
- W4317535712 hasAuthorship W4317535712A5070263915 @default.
- W4317535712 hasAuthorship W4317535712A5073576166 @default.
- W4317535712 hasBestOaLocation W43175357121 @default.
- W4317535712 hasConcept C118552586 @default.
- W4317535712 hasConcept C126322002 @default.
- W4317535712 hasConcept C168563851 @default.
- W4317535712 hasConcept C169900460 @default.
- W4317535712 hasConcept C172268261 @default.
- W4317535712 hasConcept C17744445 @default.
- W4317535712 hasConcept C197934379 @default.
- W4317535712 hasConcept C199539241 @default.
- W4317535712 hasConcept C23131810 @default.
- W4317535712 hasConcept C2776478404 @default.
- W4317535712 hasConcept C2777332695 @default.
- W4317535712 hasConcept C2778186239 @default.
- W4317535712 hasConcept C2779473830 @default.
- W4317535712 hasConcept C71924100 @default.
- W4317535712 hasConcept C95190672 @default.
- W4317535712 hasConcept C98274493 @default.
- W4317535712 hasConceptScore W4317535712C118552586 @default.
- W4317535712 hasConceptScore W4317535712C126322002 @default.
- W4317535712 hasConceptScore W4317535712C168563851 @default.
- W4317535712 hasConceptScore W4317535712C169900460 @default.
- W4317535712 hasConceptScore W4317535712C172268261 @default.
- W4317535712 hasConceptScore W4317535712C17744445 @default.
- W4317535712 hasConceptScore W4317535712C197934379 @default.
- W4317535712 hasConceptScore W4317535712C199539241 @default.
- W4317535712 hasConceptScore W4317535712C23131810 @default.