FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4317565557> ?p ?o ?g. }

• W4317565557 endingPage "7" @default.
• W4317565557 startingPage "1" @default.
• W4317565557 abstract "There are about 13 parasitic infections that are responsible for significant morbidity and mortality but have not received the attention they deserve; thus, they are now known as neglected tropical diseases (NTDs). This study was aimed at evaluating the antihelminthic activities of Lophira lanceolata using an automated high-throughput method.The antihelminthic activity effect of the extracts against H. polygyrus was determined using an automated high-throughput method. For the egg-hatching test, 100 μL of embryonated egg suspension (60 eggs) was added to 100 μL of various concentrations of extracts, levamisole, and 1.5% DMSO in a 96-well round-bottom microtitre plate. After mixing, the 96-well microplate was placed in WMicroTracker and incubated for 24 h at 25°C; the movements were recorded every 30 minutes. The same procedure was used for the larval motility assays, where 100 μL of L1 or L2 larvae (50 larvae) were put in contact with 100 μL of various concentrations of extracts.The ovicidal activity (hatching) had an IC50 of 1.4 mg/mL for the ethanol extract. The aqueous and ethanol extracts of L. lanceolata showed larvicidal activity on the L1 larvae with IC50 of 1.85 mg/mL and 2.4 mg/mL, respectively, as well as on the L2 larvae with IC50 values of 1.08 mg/mL and 1.02 mg/mL for the aqueous and ethanol extracts, respectively. These results showed that the aqueous extract exhibited a stronger inhibitory power on the hatching rate of parasites than ethanol extracts, while the contrary effect was observed for the larval motility assays.This study provides scientific data on the use of L. lanceolata by the local population for the treatment of helminthiases. However, in vivo and toxicity tests are necessary to assess its activity and safety." @default.
• W4317565557 created "2023-01-21" @default.
• W4317565557 creator A5003123877 @default.
• W4317565557 creator A5011401688 @default.
• W4317565557 creator A5011819527 @default.
• W4317565557 creator A5012597709 @default.
• W4317565557 creator A5017155371 @default.
• W4317565557 creator A5033712342 @default.
• W4317565557 creator A5060295979 @default.
• W4317565557 creator A5066158333 @default.
• W4317565557 date "2023-01-20" @default.
• W4317565557 modified "2023-10-18" @default.
• W4317565557 title "Antihelminthic Activity of Lophira Lanceolata on Heligmosomoides polygyrus Using an Automated High-Throughput Method" @default.
• W4317565557 cites W1934141242 @default.
• W4317565557 cites W1990429124 @default.
• W4317565557 cites W2002878252 @default.
• W4317565557 cites W2004150837 @default.
• W4317565557 cites W2012064591 @default.
• W4317565557 cites W2076674595 @default.
• W4317565557 cites W2108970062 @default.
• W4317565557 cites W2253656415 @default.
• W4317565557 cites W2281110269 @default.
• W4317565557 cites W2572880513 @default.
• W4317565557 cites W2743080757 @default.
• W4317565557 cites W2746703558 @default.
• W4317565557 cites W2766021880 @default.
• W4317565557 cites W2766579385 @default.
• W4317565557 cites W2797675763 @default.
• W4317565557 cites W2949179529 @default.
• W4317565557 cites W3042718739 @default.
• W4317565557 cites W3174809224 @default.
• W4317565557 cites W3199855512 @default.
• W4317565557 cites W4214897976 @default.
• W4317565557 doi "https://doi.org/10.1155/2023/9504296" @default.
• W4317565557 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36713298" @default.
• W4317565557 hasPublicationYear "2023" @default.
• W4317565557 type Work @default.
• W4317565557 citedByCount "2" @default.
• W4317565557 countsByYear W43175655572023 @default.
• W4317565557 crossrefType "journal-article" @default.
• W4317565557 hasAuthorship W4317565557A5003123877 @default.
• W4317565557 hasAuthorship W4317565557A5011401688 @default.
• W4317565557 hasAuthorship W4317565557A5011819527 @default.
• W4317565557 hasAuthorship W4317565557A5012597709 @default.
• W4317565557 hasAuthorship W4317565557A5017155371 @default.
• W4317565557 hasAuthorship W4317565557A5033712342 @default.
• W4317565557 hasAuthorship W4317565557A5060295979 @default.
• W4317565557 hasAuthorship W4317565557A5066158333 @default.
• W4317565557 hasBestOaLocation W43175655571 @default.
• W4317565557 hasConcept C140793950 @default.
• W4317565557 hasConcept C165901193 @default.
• W4317565557 hasConcept C173758957 @default.
• W4317565557 hasConcept C185592680 @default.
• W4317565557 hasConcept C18903297 @default.
• W4317565557 hasConcept C202751555 @default.
• W4317565557 hasConcept C203014093 @default.
• W4317565557 hasConcept C2776908094 @default.
• W4317565557 hasConcept C2777744765 @default.
• W4317565557 hasConcept C2777752497 @default.
• W4317565557 hasConcept C2778885919 @default.
• W4317565557 hasConcept C2780161600 @default.
• W4317565557 hasConcept C2993907526 @default.
• W4317565557 hasConcept C43617362 @default.
• W4317565557 hasConcept C55493867 @default.
• W4317565557 hasConcept C556039675 @default.
• W4317565557 hasConcept C59822182 @default.
• W4317565557 hasConcept C71924100 @default.
• W4317565557 hasConcept C86803240 @default.
• W4317565557 hasConceptScore W4317565557C140793950 @default.
• W4317565557 hasConceptScore W4317565557C165901193 @default.
• W4317565557 hasConceptScore W4317565557C173758957 @default.
• W4317565557 hasConceptScore W4317565557C185592680 @default.
• W4317565557 hasConceptScore W4317565557C18903297 @default.
• W4317565557 hasConceptScore W4317565557C202751555 @default.
• W4317565557 hasConceptScore W4317565557C203014093 @default.
• W4317565557 hasConceptScore W4317565557C2776908094 @default.
• W4317565557 hasConceptScore W4317565557C2777744765 @default.
• W4317565557 hasConceptScore W4317565557C2777752497 @default.
• W4317565557 hasConceptScore W4317565557C2778885919 @default.
• W4317565557 hasConceptScore W4317565557C2780161600 @default.
• W4317565557 hasConceptScore W4317565557C2993907526 @default.
• W4317565557 hasConceptScore W4317565557C43617362 @default.
• W4317565557 hasConceptScore W4317565557C55493867 @default.
• W4317565557 hasConceptScore W4317565557C556039675 @default.
• W4317565557 hasConceptScore W4317565557C59822182 @default.
• W4317565557 hasConceptScore W4317565557C71924100 @default.
• W4317565557 hasConceptScore W4317565557C86803240 @default.
• W4317565557 hasLocation W43175655571 @default.
• W4317565557 hasLocation W43175655572 @default.
• W4317565557 hasLocation W43175655573 @default.
• W4317565557 hasOpenAccess W4317565557 @default.
• W4317565557 hasPrimaryLocation W43175655571 @default.
• W4317565557 hasRelatedWork W1969691684 @default.
• W4317565557 hasRelatedWork W1972415631 @default.
• W4317565557 hasRelatedWork W2061239456 @default.
• W4317565557 hasRelatedWork W2074475942 @default.
• W4317565557 hasRelatedWork W2092204667 @default.
• W4317565557 hasRelatedWork W2093904317 @default.

• next