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- W4317597409 abstract "There is increasing evidence of Epstein-Barr virus (EBV) being conditional in multiple sclerosis (MS) pathogenesis and influential for disease activity. Interferon-beta (IFNβ) is a cytokine with antiviral effects used to treat MS, in which a possible antiviral effect against EBV has been questioned. In this study, we investigated the effect of IFNβ-1a treatment on serum EBV antibody levels in 84 patients with relapsing-remitting MS. In the 18 months following IFNβ-1a treatment initiation, there were no significant associations between treatment and serum levels of Epstein-Barr nuclear antigen 1 (EBNA-1) immunoglobulin (Ig) G, early antigen (EA) IgG, viral capsid antigen (VCA) IgG or VCA IgM. The findings suggest that IFNβ-1a treatment does not influence the humoral response to EBV in patients with MS." @default.
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- W4317597409 date "2023-02-01" @default.
- W4317597409 modified "2023-10-15" @default.
- W4317597409 title "Interferon β1a treatment does not influence serum Epstein-Barr virus antibodies in patients with multiple sclerosis" @default.
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- W4317597409 doi "https://doi.org/10.1016/j.msard.2023.104530" @default.
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