Matches in SemOpenAlex for { <https://semopenalex.org/work/W4317607592> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W4317607592 abstract "Abstract In this study, we consider axonal transport of large cargo vesicles characterised by transient expansion of the axon shaft. Our goal is to formulate a mathematical model which captures the dynamic mechanical interaction of such cargo vesicles with the membrane associated periodic cytoskeletal structure (MPS). It consists of regularly spaced actin rings that are transversal to the longitudinal direction of the axon and involved in the radial contraction of the axon. A system of force balance equations is formulated by which we describe the transversal rings as visco-elastic Kelvin-Voigt elements. In a homogenisation limit, we reformulate the model as a free boundary problem for the interaction of the submembranous MPS with the large vesicle. We derive a non-linear force-velocity relation as a quasi-steady state solution. Computationally we analyse the vesicle size dependence of the transport speed and use an asymptotic approximation to formulate it as a power law that can be tested experimentally." @default.
- W4317607592 created "2023-01-21" @default.
- W4317607592 creator A5053378640 @default.
- W4317607592 creator A5076178535 @default.
- W4317607592 date "2023-01-20" @default.
- W4317607592 modified "2023-09-27" @default.
- W4317607592 title "A mathematical model for axonal transport of large cargo vesicles" @default.
- W4317607592 cites W1542210644 @default.
- W4317607592 cites W1989821468 @default.
- W4317607592 cites W2014444307 @default.
- W4317607592 cites W2039830655 @default.
- W4317607592 cites W2046529900 @default.
- W4317607592 cites W2065490663 @default.
- W4317607592 cites W2071131107 @default.
- W4317607592 cites W2084034472 @default.
- W4317607592 cites W2112297277 @default.
- W4317607592 cites W2147929960 @default.
- W4317607592 cites W2158190317 @default.
- W4317607592 cites W2227100252 @default.
- W4317607592 cites W2314116290 @default.
- W4317607592 cites W2737711489 @default.
- W4317607592 cites W2765516952 @default.
- W4317607592 cites W2804776485 @default.
- W4317607592 cites W2891674619 @default.
- W4317607592 cites W2966389233 @default.
- W4317607592 cites W2995073429 @default.
- W4317607592 cites W3011853439 @default.
- W4317607592 cites W3017347363 @default.
- W4317607592 cites W3167610381 @default.
- W4317607592 cites W3188229263 @default.
- W4317607592 doi "https://doi.org/10.1101/2023.01.18.524542" @default.
- W4317607592 hasPublicationYear "2023" @default.
- W4317607592 type Work @default.
- W4317607592 citedByCount "0" @default.
- W4317607592 crossrefType "posted-content" @default.
- W4317607592 hasAuthorship W4317607592A5053378640 @default.
- W4317607592 hasAuthorship W4317607592A5076178535 @default.
- W4317607592 hasBestOaLocation W43176075921 @default.
- W4317607592 hasConcept C121332964 @default.
- W4317607592 hasConcept C130316041 @default.
- W4317607592 hasConcept C134306372 @default.
- W4317607592 hasConcept C142669718 @default.
- W4317607592 hasConcept C1491633281 @default.
- W4317607592 hasConcept C169760540 @default.
- W4317607592 hasConcept C185592680 @default.
- W4317607592 hasConcept C2779530196 @default.
- W4317607592 hasConcept C2780130068 @default.
- W4317607592 hasConcept C33923547 @default.
- W4317607592 hasConcept C41625074 @default.
- W4317607592 hasConcept C55493867 @default.
- W4317607592 hasConcept C57879066 @default.
- W4317607592 hasConcept C74650414 @default.
- W4317607592 hasConcept C86803240 @default.
- W4317607592 hasConceptScore W4317607592C121332964 @default.
- W4317607592 hasConceptScore W4317607592C130316041 @default.
- W4317607592 hasConceptScore W4317607592C134306372 @default.
- W4317607592 hasConceptScore W4317607592C142669718 @default.
- W4317607592 hasConceptScore W4317607592C1491633281 @default.
- W4317607592 hasConceptScore W4317607592C169760540 @default.
- W4317607592 hasConceptScore W4317607592C185592680 @default.
- W4317607592 hasConceptScore W4317607592C2779530196 @default.
- W4317607592 hasConceptScore W4317607592C2780130068 @default.
- W4317607592 hasConceptScore W4317607592C33923547 @default.
- W4317607592 hasConceptScore W4317607592C41625074 @default.
- W4317607592 hasConceptScore W4317607592C55493867 @default.
- W4317607592 hasConceptScore W4317607592C57879066 @default.
- W4317607592 hasConceptScore W4317607592C74650414 @default.
- W4317607592 hasConceptScore W4317607592C86803240 @default.
- W4317607592 hasLocation W43176075921 @default.
- W4317607592 hasOpenAccess W4317607592 @default.
- W4317607592 hasPrimaryLocation W43176075921 @default.
- W4317607592 hasRelatedWork W1655643580 @default.
- W4317607592 hasRelatedWork W1892403772 @default.
- W4317607592 hasRelatedWork W1996218007 @default.
- W4317607592 hasRelatedWork W2025663109 @default.
- W4317607592 hasRelatedWork W2032943952 @default.
- W4317607592 hasRelatedWork W2043263915 @default.
- W4317607592 hasRelatedWork W2159836027 @default.
- W4317607592 hasRelatedWork W2412881298 @default.
- W4317607592 hasRelatedWork W298416947 @default.
- W4317607592 hasRelatedWork W4317607592 @default.
- W4317607592 isParatext "false" @default.
- W4317607592 isRetracted "false" @default.
- W4317607592 workType "article" @default.