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- W4317624054 abstract "As COVID-19 vaccines moved from the controlled environment of clinical trials to use in real-world settings, it has been important to evaluate vaccine effectiveness. A retrospective cohort study was designed to identify cases of SARS-CoV-2 infection that occurred between January 17-June 30, 2021 in fully vaccinated Virginia residents. Of the fully vaccinated population of Virginia at the end of the study period (N = 4,271,505), 2445 (0.057 %) were reported to have experienced a vaccine breakthrough infection. Of those, 183 (7.5 %) were reported to have been hospitalized for COVID-19 and 53 (2.2 %) died from COVID-19. There were significant differences in vaccine effectiveness over time between both mRNA vaccines and the Janssen vaccine. Increasing age, pre-existing medical conditions, and male sex were associated with severe outcomes (hospitalization or death). Persons at greater risk for severe outcomes should continue to take precautions to prevent SARS-CoV-2 infection, even if fully vaccinated." @default.
- W4317624054 created "2023-01-21" @default.
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- W4317624054 date "2023-02-01" @default.
- W4317624054 modified "2023-09-30" @default.
- W4317624054 title "SARS-CoV-2 vaccine breakthrough infections in Virginia, January 17, 2021 – June 30, 2021" @default.
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- W4317624054 doi "https://doi.org/10.1016/j.vaccine.2023.01.041" @default.
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