Matches in SemOpenAlex for { <https://semopenalex.org/work/W4317702940> ?p ?o ?g. }
- W4317702940 abstract "During intracellular signal transduction, protein-protein interactions (PPIs) facilitate protein complex assembly to regulate protein localization and function, which are critical for numerous cellular events. Over the years, multiple techniques have been developed to characterize PPIs to elucidate roles and regulatory mechanisms of proteins. Among them, the mass spectrometry (MS)-based interactome analysis has been increasing in popularity due to its unbiased and informative manner towards understanding PPI networks. However, with MS instrumentation advancing and yielding more data than ever, the analysis of a large amount of PPI-associated proteomic data to reveal bona fide interacting proteins become challenging. Here, we review the methods and bioinformatic resources that are commonly used in analyzing large interactome-related proteomic data and propose a simple guideline for identifying novel interacting proteins for biological research." @default.
- W4317702940 created "2023-01-22" @default.
- W4317702940 creator A5076871243 @default.
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- W4317702940 date "2023-01-22" @default.
- W4317702940 modified "2023-10-03" @default.
- W4317702940 title "Analysis of affinity purification-related proteomic data for studying protein–protein interaction networks in cells" @default.
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- W4317702940 doi "https://doi.org/10.1093/bib/bbad010" @default.
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