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- W4317753376 abstract "Abstract For improved safety, children are vaccinated with a lower dose and extended interval for mRNA COVID-19 vaccines; however, whether there is protection before dose 2 is unknown. We recruited 113 children receiving BNT162b2 primary vaccination during an Omicron wave. After dose 1, 96% had detectable anti-Spike(S) IgG and 100% had S-reactive T cells; those with both had a lower risk of symptomatic infection compared to those with undetectable anti-S IgG [RR 0.19 (95% CI; 0.06, 0.59)]. This suggests that dosing can be extended without risk of insufficient early protection." @default.
- W4317753376 created "2023-01-23" @default.
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- W4317753376 date "2023-01-23" @default.
- W4317753376 modified "2023-10-14" @default.
- W4317753376 title "Early induction of anti-Spike binding antibodies and T cells confer protection against COVID-19 in children during an Omicron wave" @default.
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- W4317753376 doi "https://doi.org/10.21203/rs.3.rs-2421432/v1" @default.
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