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• W4317778813 abstract "A medication review can be defined as a structured evaluation of a patient's medication conducted by healthcare professionals with the aim of optimising medication use and improving health outcomes. Optimising medication therapy though medication reviews may benefit hospitalised patients.We examined the effects of medication review interventions in hospitalised adult patients compared to standard care or to other types of medication reviews on all-cause mortality, hospital readmissions, emergency department contacts and health-related quality of life.In this Cochrane Review update, we searched for new published and unpublished trials using the following electronic databases from 1 January 2014 to 17 January 2022 without language restrictions: the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, Embase, the Cumulative Index to Nursing and Allied Health Literature (CINAHL), ClinicalTrials.gov and the WHO International Clinical Trials Registry Platform (ICTRP). To identify additional trials, we searched the reference lists of included trials and other publications by lead trial authors, and contacted experts.We included randomised trials of medication reviews delivered by healthcare professionals for hospitalised adult patients. We excluded trials including outpatients and paediatric patients.Two review authors independently selected trials, extracted data and assessed risk of bias. We contacted trial authors for data clarification and relevant unpublished data. We calculated risk ratios (RRs) for dichotomous data and mean differences (MDs) or standardised mean differences (SMDs) for continuous data (with 95% confidence intervals (CIs)). We used the GRADE (Grades of Recommendation, Assessment, Development and Evaluation) approach to assess the overall certainty of the evidence.In this updated review, we included a total of 25 trials (15,076 participants), of which 15 were new trials (11,501 participants). Follow-up ranged from 1 to 20 months. We found that medication reviews in hospitalised adults may have little to no effect on mortality (RR 0.96, 95% CI 0.87 to 1.05; 18 trials, 10,108 participants; low-certainty evidence); likely reduce hospital readmissions (RR 0.93, 95% CI 0.89 to 0.98; 17 trials, 9561 participants; moderate-certainty evidence); may reduce emergency department contacts (RR 0.84, 95% CI 0.68 to 1.03; 8 trials, 3527 participants; low-certainty evidence) and have very uncertain effects on health-related quality of life (SMD 0.10, 95% CI -0.10 to 0.30; 4 trials, 392 participants; very low-certainty evidence).Medication reviews in hospitalised adult patients likely reduce hospital readmissions and may reduce emergency department contacts. The evidence suggests that mediation reviews may have little to no effect on mortality, while the effect on health-related quality of life is very uncertain. Almost all trials included elderly polypharmacy patients, which limits the generalisability of the results beyond this population." @default.
• W4317778813 created "2023-01-24" @default.
• W4317778813 creator A5000183899 @default.
• W4317778813 creator A5051382562 @default.
• W4317778813 creator A5069384100 @default.
• W4317778813 creator A5085154673 @default.
• W4317778813 date "2023-01-23" @default.
• W4317778813 modified "2023-10-01" @default.
• W4317778813 title "Medication review in hospitalised patients to reduce morbidity and mortality" @default.
• W4317778813 cites W1497147944 @default.
• W4317778813 cites W1524993883 @default.
• W4317778813 cites W1554742340 @default.
• W4317778813 cites W1577933580 @default.
• W4317778813 cites W1719489384 @default.
• W4317778813 cites W1766940943 @default.
• W4317778813 cites W1779003791 @default.
• W4317778813 cites W1828049375 @default.
• W4317778813 cites W1846375292 @default.
• W4317778813 cites W1900123011 @default.
• W4317778813 cites W1933272603 @default.
• W4317778813 cites W1938137431 @default.
• W4317778813 cites W1951946799 @default.
• W4317778813 cites W1960825776 @default.
• W4317778813 cites W1963867953 @default.
• W4317778813 cites W1965022993 @default.
• W4317778813 cites W1967919392 @default.
• W4317778813 cites W1968030991 @default.
• W4317778813 cites W1969605616 @default.
• W4317778813 cites W1971892342 @default.
• W4317778813 cites W1972800032 @default.
• W4317778813 cites W1973139514 @default.
• W4317778813 cites W1976362975 @default.
• W4317778813 cites W1977818241 @default.
• W4317778813 cites W1979735814 @default.
• W4317778813 cites W1983044640 @default.
• W4317778813 cites W1984223563 @default.
• W4317778813 cites W1986689424 @default.
• W4317778813 cites W1990555364 @default.
• W4317778813 cites W1995159387 @default.
• W4317778813 cites W1996980758 @default.
• W4317778813 cites W1998724400 @default.
• W4317778813 cites W1999105095 @default.
• W4317778813 cites W2000329583 @default.
• W4317778813 cites W2001899046 @default.
• W4317778813 cites W2005287859 @default.
• W4317778813 cites W2005942653 @default.
• W4317778813 cites W2012575785 @default.
• W4317778813 cites W2013320151 @default.
• W4317778813 cites W2017978677 @default.
• W4317778813 cites W2018447534 @default.
• W4317778813 cites W2027851081 @default.
• W4317778813 cites W2037674409 @default.
• W4317778813 cites W2039870490 @default.
• W4317778813 cites W2040308765 @default.
• W4317778813 cites W2044329231 @default.
• W4317778813 cites W2048781692 @default.
• W4317778813 cites W2049742472 @default.
• W4317778813 cites W2052341320 @default.
• W4317778813 cites W2053260541 @default.
• W4317778813 cites W2055245690 @default.
• W4317778813 cites W2056108270 @default.
• W4317778813 cites W2057906307 @default.
• W4317778813 cites W2058699915 @default.
• W4317778813 cites W2060706173 @default.
• W4317778813 cites W2062096263 @default.
• W4317778813 cites W2063508762 @default.
• W4317778813 cites W2064470295 @default.
• W4317778813 cites W2070501236 @default.
• W4317778813 cites W2079842711 @default.
• W4317778813 cites W2084168083 @default.
• W4317778813 cites W2084392662 @default.
• W4317778813 cites W2098310266 @default.
• W4317778813 cites W2098891980 @default.
• W4317778813 cites W2104471440 @default.
• W4317778813 cites W2110166542 @default.
• W4317778813 cites W2113525252 @default.
• W4317778813 cites W2113781893 @default.
• W4317778813 cites W2121336886 @default.
• W4317778813 cites W2125511618 @default.
• W4317778813 cites W2130510785 @default.
• W4317778813 cites W2133346238 @default.
• W4317778813 cites W2134845326 @default.
• W4317778813 cites W2135014517 @default.
• W4317778813 cites W2140920443 @default.
• W4317778813 cites W2142901177 @default.
• W4317778813 cites W2143189399 @default.
• W4317778813 cites W2149485684 @default.
• W4317778813 cites W2149996523 @default.
• W4317778813 cites W2152755639 @default.
• W4317778813 cites W2153827064 @default.
• W4317778813 cites W2154360526 @default.
• W4317778813 cites W2156805393 @default.
• W4317778813 cites W2161228932 @default.
• W4317778813 cites W2163313694 @default.
• W4317778813 cites W2165010366 @default.
• W4317778813 cites W2171787586 @default.
• W4317778813 cites W2179532442 @default.
• W4317778813 cites W2215531932 @default.
• W4317778813 cites W2225022024 @default.
• W4317778813 cites W2254641159 @default.

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