FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4317788451> ?p ?o ?g. }

• W4317788451 abstract "Abstract Background There is a growing concern with inappropriate, excessive perioperative blood transfusions. Understanding the influence of low preoperative hemoglobin (Hgb) on perioperative blood transfusion (PBT) in head and neck cancer (HNC) surgery with free flap reconstruction may help guide clinical practice to reduce inappropriate treatment among these patients. The objective is to synthesize evidence regarding the association between preoperative Hgb and PBT among major HNC free flap surgeries. Methods Terms and synonyms for HNC surgical procedures, Hgb and PBT were used to search MEDLINE, Embase, CINAHL, Cochrane Central Register of Controlled Trials and Cochrane Database of Reviews from inception to February 2020. Reference lists of included full texts and studies reporting the preoperative Hgb, anemia or hematocrit (exposure) and the PBT (outcome) in major HNC surgery with free flap reconstruction were eligible. Studies examining esophageal, thyroid and parathyroid neoplasms were excluded; as were case reports, case series (n < 20), editorials, reviews, perspectives, viewpoints and responses. Two independent, blinded reviewers screened titles, abstracts and full texts in duplicate. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses was followed. A random-effects model was used to pool reported data. The primary outcome was the proportion of patients who had a PBT. Subgroup analysis examined sources of heterogeneity for perioperative predictors of PBT (age, sex, flap type, flap site and preoperative Hgb). We also examined mean preoperative Hgb in the PBT and no PBT groups. Results Patients with low preoperative Hgb were transfused more than those with normal Hgb (47.62%, 95% CI = 41.19–54.06, I 2 = 0.00% and 13.92%, 95% CI = 10.19–17.65, I 2 = 20.69%, respectively). None of the predictor variables explained PBT. The overall pooled mean preoperative Hgb was 12.96 g/dL (95% CI = 11.33–14.59, I 2 = 0.00%) and was 13.58 g/dL (95% CI = 11.95–15.21, I 2 = 0.00%) in the no PBT group and 12.05 g/dL (95% CI = 10.01 to 14.09, I 2 = 0.00%) in the PBT group. Conclusions The heterogeneity between studies, especially around the trigger for PBT, highlights the need for additional research to guide clinical practice of preoperative Hgb related to PBT to enhance patient outcomes and improve healthcare stewardship. Graphical abstract" @default.
• W4317788451 created "2023-01-24" @default.
• W4317788451 creator A5042147907 @default.
• W4317788451 creator A5062172932 @default.
• W4317788451 creator A5078233820 @default.
• W4317788451 date "2023-01-24" @default.
• W4317788451 modified "2023-10-17" @default.
• W4317788451 title "Preoperative hemoglobin and perioperative blood transfusion in major head and neck surgery: a systematic review and meta-analysis" @default.
• W4317788451 cites W1484306822 @default.
• W4317788451 cites W1548498169 @default.
• W4317788451 cites W157814876 @default.
• W4317788451 cites W1860890163 @default.
• W4317788451 cites W1965193139 @default.
• W4317788451 cites W1968716619 @default.
• W4317788451 cites W1977167224 @default.
• W4317788451 cites W1985678350 @default.
• W4317788451 cites W1988351795 @default.
• W4317788451 cites W2001453738 @default.
• W4317788451 cites W2007320066 @default.
• W4317788451 cites W2016724200 @default.
• W4317788451 cites W2021762717 @default.
• W4317788451 cites W2049863248 @default.
• W4317788451 cites W2050065318 @default.
• W4317788451 cites W2060836097 @default.
• W4317788451 cites W2077534582 @default.
• W4317788451 cites W2080195599 @default.
• W4317788451 cites W2083705276 @default.
• W4317788451 cites W2086515513 @default.
• W4317788451 cites W2091359154 @default.
• W4317788451 cites W2092205534 @default.
• W4317788451 cites W2093762025 @default.
• W4317788451 cites W2105860710 @default.
• W4317788451 cites W2108646241 @default.
• W4317788451 cites W2109973294 @default.
• W4317788451 cites W2119647715 @default.
• W4317788451 cites W2124363070 @default.
• W4317788451 cites W2126707535 @default.
• W4317788451 cites W2134833483 @default.
• W4317788451 cites W2139331374 @default.
• W4317788451 cites W2140043294 @default.
• W4317788451 cites W2142336027 @default.
• W4317788451 cites W2145474852 @default.
• W4317788451 cites W2152617289 @default.
• W4317788451 cites W2158148274 @default.
• W4317788451 cites W2162192696 @default.
• W4317788451 cites W2187967006 @default.
• W4317788451 cites W2313290093 @default.
• W4317788451 cites W2321770168 @default.
• W4317788451 cites W2372408240 @default.
• W4317788451 cites W2416320090 @default.
• W4317788451 cites W2509435966 @default.
• W4317788451 cites W2792721781 @default.
• W4317788451 cites W2889646458 @default.
• W4317788451 cites W2899995473 @default.
• W4317788451 cites W2927638981 @default.
• W4317788451 cites W2943025443 @default.
• W4317788451 cites W2945544890 @default.
• W4317788451 cites W2967871826 @default.
• W4317788451 cites W2995239303 @default.
• W4317788451 cites W3149204147 @default.
• W4317788451 cites W3209351266 @default.
• W4317788451 cites W40454501 @default.
• W4317788451 cites W4243445576 @default.
• W4317788451 cites W72768312 @default.
• W4317788451 doi "https://doi.org/10.1186/s40463-022-00588-4" @default.
• W4317788451 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36691071" @default.
• W4317788451 hasPublicationYear "2023" @default.
• W4317788451 type Work @default.
• W4317788451 citedByCount "1" @default.
• W4317788451 crossrefType "journal-article" @default.
• W4317788451 hasAuthorship W4317788451A5042147907 @default.
• W4317788451 hasAuthorship W4317788451A5062172932 @default.
• W4317788451 hasAuthorship W4317788451A5078233820 @default.
• W4317788451 hasBestOaLocation W43177884511 @default.
• W4317788451 hasConcept C126322002 @default.
• W4317788451 hasConcept C141071460 @default.
• W4317788451 hasConcept C17744445 @default.
• W4317788451 hasConcept C189708586 @default.
• W4317788451 hasConcept C199539241 @default.
• W4317788451 hasConcept C2776478404 @default.
• W4317788451 hasConcept C2778248108 @default.
• W4317788451 hasConcept C2779473830 @default.
• W4317788451 hasConcept C2780014101 @default.
• W4317788451 hasConcept C2780959883 @default.
• W4317788451 hasConcept C31174226 @default.
• W4317788451 hasConcept C71924100 @default.
• W4317788451 hasConcept C95190672 @default.
• W4317788451 hasConceptScore W4317788451C126322002 @default.
• W4317788451 hasConceptScore W4317788451C141071460 @default.
• W4317788451 hasConceptScore W4317788451C17744445 @default.
• W4317788451 hasConceptScore W4317788451C189708586 @default.
• W4317788451 hasConceptScore W4317788451C199539241 @default.
• W4317788451 hasConceptScore W4317788451C2776478404 @default.
• W4317788451 hasConceptScore W4317788451C2778248108 @default.
• W4317788451 hasConceptScore W4317788451C2779473830 @default.
• W4317788451 hasConceptScore W4317788451C2780014101 @default.
• W4317788451 hasConceptScore W4317788451C2780959883 @default.
• W4317788451 hasConceptScore W4317788451C31174226 @default.
• W4317788451 hasConceptScore W4317788451C71924100 @default.
• W4317788451 hasConceptScore W4317788451C95190672 @default.

• next