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• W4317802021 abstract "Post-resuscitation care in intensive care units (ICU) includes control of oxygenation, hemodynamic and targeted temperature management (TTM), multimodal prognostication and rehabilitation. The level of evidence on the effectiveness of these measures on outcomes remains insufficient. We aimed to evaluate ICUs practices after successful cardiac arrest (CA) resuscitation. During July 2022, we conducted a national survey of practices in French ICU using a 28-question questionnaire available online. 349 ICUs were surveyed. 95 completed the questionnaire. 57.9% of the responders had been working in ICU for more than 10 years. 34.7% worked in a teaching hospital, 58.9% worked in a general hospital. 96.8% responders used a TTM strategy but only 46.3% of them used a written protocol. 7.4% responders had different temperature targets between out-of-hospital CA and in-hospital CA and 9.5% had different temperature targets depending on CA cause (shockable versus non-shockable rhythm). In ICU using the same TTM strategy for all CA patients (86.3%), 68.3% targeted 36 °C, 25.6% targeted a temperature ranging from 32 to 34 °C and 6.1% targeted normothermia (temperature < 37,8°C). 98.9% used a sedation while TTM. TTM lasted for 24 hours for 87.4% of the responders and for more than 24 hours for 10,5%. First-line sedative was propofol, midazolam and inhaled sedation for respectively 58.5%, 35.1% and 10.6% of intensivists. 98.9% targeted a normal arterial partial pressure of carbon dioxide (PaCO2 35–45 mmHg). 96.8% targeted a mean arterial pressure (MAP) superior to 65 mmHg and 3.2% a mean arterial pressure superior to 80 mmHg. None of the responders started neurological prognostication before 24 hours after CA. 38.9% started neurological prognostication between 24 and 72 hours after CA, 45.3% between 72 and 96 hours and 15,8% after 96 hours. Only 25.3% responders used a written neurological prognostication protocol. Most used tests for neurological prognostication included electroencephalogram (96.8%), biological marker NSE (86.3%), cerebral magnetic resonance imaging (51.6%), somatosensory evoked potentials (N20 wave) (50.5%) and cerebral computed tomography (45.3%). 17.9% responders organized long-term follow-up for CA survivors after hospital discharge. This study aimed to clarify current post-resuscitation care in ICU in France. The results showed that most participating ICU were aware and in accordance with ILCOR guidelines 1Wyckoff M.H. Singletary E.M. Soar J. et al.2021 International consensus on cardiopulmonary resuscitation and emergency cardiovascular care science with treatment recommendations: summary from the basic life support; advanced life support; neonatal life support; education, implementation, and teams; first aid task forces; and the COVID-19 working group.Resuscitation. 2021; 169: 229-311Abstract Full Text Full Text PDF PubMed Scopus (48) Google Scholar. In accordance with literature, a 36 °C TTM seems to have become the standard of care in French ICU 2Nielsen N. Wetterslev J. Cronberg T. et al.Targeted temperature management at 33°C versus 36°C after cardiac arrest.N Engl J Med. 2013; 369: 2197-2206Crossref PubMed Scopus (2071) Google Scholar. However, avoiding fever was not the most chosen treatment, the reasons not to change practice are not known. Perhaps our questionnaire was done too early with regard to the release of TTM 2 3Dankiewicz J. Cronberg T. Lilja G. et al.Hypothermia versus normothermia after out-of-hospital cardiac arrest.N Engl J Med. 2021; 384: 2283-2294Crossref PubMed Scopus (339) Google Scholar. However should we tailor the TTM according to patient’s individual risk 4Lascarrou J.B. Dumas F. Bougouin W. et al.differential effect of targeted temperature management between 32°C and 36°C following cardiac arrest according to initial severity of illness: insights from two international data sets.Chest. 2022; S0012-3692: 04037-5Google Scholar? Practices regarding MAP and PaCO2 were uniform but may change with future study results (NCT05486884, NCT03114033). The use of paraclinical tests for prognostication was disparate, probably depending on the accessibility of each test in different settings. Less than a fifth of CA survivors in France have a multidisciplinary evaluation after ICU discharge. Studies are needed to assess the prognostic value of such measures 5Joshi V.L. Christensen J. Lejsgaard E. Taylor R.S. Zwisler A.D. Tang L.H. Effectiveness of rehabilitation interventions on the secondary consequences of surviving a cardiac arrest: a systematic review and meta-analysis.BMJ Open. 2021; 11: e047251Crossref PubMed Scopus (5) Google Scholar. Despite knowledge gaps in post-resuscitation care, the ILCOR recommendations seem to be well established in French ICUs (see Fig. 1). None." @default.
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• W4317802021 date "2023-03-01" @default.
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• W4317802021 title "Post-resuscitation care following cardiac arrest in intensive care units: A French national survey" @default.
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• W4317802021 doi "https://doi.org/10.1016/j.resuscitation.2023.109701" @default.
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