FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4317811485> ?p ?o ?g. }

• W4317811485 endingPage "212" @default.
• W4317811485 startingPage "212" @default.
• W4317811485 abstract "The choroid plexus (CP) is a structure in the brain ventricles that produces the main part of the cerebrospinal fluid (CSF). It is covered with specialized cells which show epithelial characteristics and are the site of the blood-CSF barrier. These cells form a contiguous cell sheet with ventricle-lining ependymal cells which are known to express aquaporin-4 (AQP4). In contrast, CP epithelial cells express aquaporin-1 (AQP1) apically. We investigated the expression patterns of aquaporins in the CP-ependyma transition from human body donors using immunofluorescence and electron microscopy. Ependymal cells and subependymal astrocytes at the base of the CP showed a particularly high AQP4 immunoreactivity. Astrocytic processes formed a dense meshwork or glial plate around the blood vessels entering the CP. Interestingly, some of these astrocytic processes were in direct contact with the CP stroma, which contains fenestrated blood vessels, separated only by a basal lamina. Electron microscopy confirmed the continuity of the subastrocytic basal lamina with the CP epithelium. We also probed for components of the AQP4 anchoring dystrophin-dystroglycan complex. Immunolabeling for dystrophin and AQP4 showed an overlapping staining pattern in the glial plate but not in previously reported AQP4-positive CP epithelial cells. In contrast, dystroglycan expression was associated with laminin staining in the glial plate and the CP epithelium. This suggests different mechanisms for AQP4 anchoring in the cell membrane. The high AQP4 density in the connecting glial plate might facilitate the transport of water in and out of the CP stroma and could possibly serve as a drainage and clearing pathway for metabolites." @default.
• W4317811485 created "2023-01-24" @default.
• W4317811485 creator A5012042453 @default.
• W4317811485 creator A5013544005 @default.
• W4317811485 creator A5028770358 @default.
• W4317811485 creator A5053554667 @default.
• W4317811485 creator A5054388362 @default.
• W4317811485 creator A5081286371 @default.
• W4317811485 date "2023-01-22" @default.
• W4317811485 modified "2023-10-18" @default.
• W4317811485 title "Aquaporin-1 and Aquaporin-4 Expression in Ependyma, Choroid Plexus and Surrounding Transition Zones in the Human Brain" @default.
• W4317811485 cites W1492555480 @default.
• W4317811485 cites W1535419310 @default.
• W4317811485 cites W1570470449 @default.
• W4317811485 cites W1894872962 @default.
• W4317811485 cites W1967001670 @default.
• W4317811485 cites W1974587361 @default.
• W4317811485 cites W1988296977 @default.
• W4317811485 cites W1993064394 @default.
• W4317811485 cites W2001535098 @default.
• W4317811485 cites W2003071851 @default.
• W4317811485 cites W2004630293 @default.
• W4317811485 cites W2006749910 @default.
• W4317811485 cites W2009059228 @default.
• W4317811485 cites W2015065886 @default.
• W4317811485 cites W2036610870 @default.
• W4317811485 cites W2037919781 @default.
• W4317811485 cites W2047705892 @default.
• W4317811485 cites W2057226095 @default.
• W4317811485 cites W2059672640 @default.
• W4317811485 cites W2059761294 @default.
• W4317811485 cites W2072251236 @default.
• W4317811485 cites W2072942642 @default.
• W4317811485 cites W2080466385 @default.
• W4317811485 cites W2087666006 @default.
• W4317811485 cites W2092989707 @default.
• W4317811485 cites W2096230518 @default.
• W4317811485 cites W2154880249 @default.
• W4317811485 cites W2155925021 @default.
• W4317811485 cites W2159821105 @default.
• W4317811485 cites W2167183660 @default.
• W4317811485 cites W2175101137 @default.
• W4317811485 cites W2566186841 @default.
• W4317811485 cites W2600812978 @default.
• W4317811485 cites W2755152678 @default.
• W4317811485 cites W2787246109 @default.
• W4317811485 cites W3004007615 @default.
• W4317811485 cites W3007075554 @default.
• W4317811485 cites W3081165541 @default.
• W4317811485 cites W3091991801 @default.
• W4317811485 cites W3109308881 @default.
• W4317811485 cites W3152893457 @default.
• W4317811485 cites W3200269154 @default.
• W4317811485 cites W3201046483 @default.
• W4317811485 cites W4207043776 @default.
• W4317811485 cites W4214574386 @default.
• W4317811485 doi "https://doi.org/10.3390/biom13020212" @default.
• W4317811485 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36830582" @default.
• W4317811485 hasPublicationYear "2023" @default.
• W4317811485 type Work @default.
• W4317811485 citedByCount "1" @default.
• W4317811485 countsByYear W43178114852023 @default.
• W4317811485 crossrefType "journal-article" @default.
• W4317811485 hasAuthorship W4317811485A5012042453 @default.
• W4317811485 hasAuthorship W4317811485A5013544005 @default.
• W4317811485 hasAuthorship W4317811485A5028770358 @default.
• W4317811485 hasAuthorship W4317811485A5053554667 @default.
• W4317811485 hasAuthorship W4317811485A5054388362 @default.
• W4317811485 hasAuthorship W4317811485A5081286371 @default.
• W4317811485 hasBestOaLocation W43178114851 @default.
• W4317811485 hasConcept C105702510 @default.
• W4317811485 hasConcept C127413603 @default.
• W4317811485 hasConcept C142724271 @default.
• W4317811485 hasConcept C15755913 @default.
• W4317811485 hasConcept C169760540 @default.
• W4317811485 hasConcept C177586851 @default.
• W4317811485 hasConcept C185592680 @default.
• W4317811485 hasConcept C189165786 @default.
• W4317811485 hasConcept C201289731 @default.
• W4317811485 hasConcept C2775845273 @default.
• W4317811485 hasConcept C2776538271 @default.
• W4317811485 hasConcept C2776663378 @default.
• W4317811485 hasConcept C2778384963 @default.
• W4317811485 hasConcept C2778402981 @default.
• W4317811485 hasConcept C2779333224 @default.
• W4317811485 hasConcept C2779814568 @default.
• W4317811485 hasConcept C2780775167 @default.
• W4317811485 hasConcept C2909073510 @default.
• W4317811485 hasConcept C529278444 @default.
• W4317811485 hasConcept C71924100 @default.
• W4317811485 hasConcept C78519656 @default.
• W4317811485 hasConcept C86803240 @default.
• W4317811485 hasConcept C87555872 @default.
• W4317811485 hasConcept C95444343 @default.
• W4317811485 hasConceptScore W4317811485C105702510 @default.
• W4317811485 hasConceptScore W4317811485C127413603 @default.
• W4317811485 hasConceptScore W4317811485C142724271 @default.
• W4317811485 hasConceptScore W4317811485C15755913 @default.

• next