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- W4317813234 endingPage "2111" @default.
- W4317813234 startingPage "2111" @default.
- W4317813234 abstract "Glioblastoma (GBM) is the most aggressive and malignant primary brain tumor in adults. Despite multimodality treatment involving surgical resection, radiation therapy, chemotherapy, and tumor-treating fields, the median overall survival (OS) after diagnosis is approximately 2 years and the 5-year OS is poor. Considering the poor prognosis, novel treatment strategies are needed, such as immunotherapies, which include chimeric antigen receptor T-cell therapy, immune checkpoint inhibitors, vaccine therapy, and oncolytic virus therapy. However, these therapies have not achieved satisfactory outcomes. One reason for this is that these therapies are mainly based on activating T cells and controlling GBM progression. Natural killer (NK) cell-based immunotherapy involves the new feature of recognizing GBM via differing mechanisms from that of T cell-based immunotherapy. In this review, we focused on NK cell-based immunotherapy as a novel GBM treatment strategy." @default.
- W4317813234 created "2023-01-24" @default.
- W4317813234 creator A5002163440 @default.
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- W4317813234 creator A5078888657 @default.
- W4317813234 creator A5087179801 @default.
- W4317813234 date "2023-01-20" @default.
- W4317813234 modified "2023-10-05" @default.
- W4317813234 title "Natural Killer Cell-Based Immunotherapy against Glioblastoma" @default.
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