FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4317863179> ?p ?o ?g. }

• W4317863179 endingPage "644" @default.
• W4317863179 startingPage "635" @default.
• W4317863179 abstract "INTRODUCTION: The economic and clinical implications of eradicating Helicobacter pylori ( H. pylori ) with vonoprazan-based and rifabutin-based regimens vs other existing prepackaged first-line treatment options in the United States are unknown. Therefore, we evaluated the cost-effectiveness of vonoprazan-based and rifabutin-based and other prepackaged regimens for the first-line treatment of H. pylori from the perspective of US healthcare payers. METHODS: We used the state-transition Markov model to conduct a cost-effectiveness analysis of H. pylori eradication with clarithromycin triple, bismuth quadruple, vonoprazan dual, vonoprazan triple, and rifabutin triple regimens. In a cycle length of 2 months, the model estimated the expected costs (expressed in 2022 US$), expected quality-adjusted life-years (QALY), incremental cost-effectiveness ratios, and expected net monetary benefit over 20 years. In addition, we accounted for the present value of future costs and QALY by applying a 3% discounting rate. RESULTS: In this study, rifabutin triple therapy had a lower expected cost but was more effective than clarithromycin triple, bismuth quadruple, and vonoprazan dual regimens; hence, it dominated them. Vonoprazan triple therapy had a higher expected cost (US$ 1,172 vs US$ 1,048) and expected QALY (14.262 vs 14.256) than rifabutin triple therapy, yielding an estimated incremental cost-effectiveness ratio of US$ 22,573/QALY. The study suggested that vonoprazan triple treatment had the highest expected net monetary benefit and was the most cost-effective at willingness-to-pay thresholds between US$50,000 and US$150,000 per QALY, followed by rifabutin triple therapy. DISCUSSION: H. pylori infection eradication with vonoprazan triple therapy would provide the greatest net health and monetary benefit from the perspective of US healthcare payers." @default.
• W4317863179 created "2023-01-25" @default.
• W4317863179 creator A5013149128 @default.
• W4317863179 creator A5044432895 @default.
• W4317863179 date "2022-12-14" @default.
• W4317863179 modified "2023-09-27" @default.
• W4317863179 title "Cost-Effectiveness of Vonoprazan-Based and Rifabutin-Based vs Other Regimens as First-Line Treatment of Helicobacter pylori Infection in the United States" @default.
• W4317863179 cites W1916371443 @default.
• W4317863179 cites W1964852767 @default.
• W4317863179 cites W1972818247 @default.
• W4317863179 cites W1974946414 @default.
• W4317863179 cites W2058056848 @default.
• W4317863179 cites W2061382057 @default.
• W4317863179 cites W2064401560 @default.
• W4317863179 cites W2085500228 @default.
• W4317863179 cites W2097764311 @default.
• W4317863179 cites W2105568027 @default.
• W4317863179 cites W2115558585 @default.
• W4317863179 cites W2127908702 @default.
• W4317863179 cites W2131553265 @default.
• W4317863179 cites W2145327797 @default.
• W4317863179 cites W2148370712 @default.
• W4317863179 cites W2152211277 @default.
• W4317863179 cites W2156582040 @default.
• W4317863179 cites W2157650397 @default.
• W4317863179 cites W2164654252 @default.
• W4317863179 cites W2170239385 @default.
• W4317863179 cites W2183787411 @default.
• W4317863179 cites W2301012193 @default.
• W4317863179 cites W2318393109 @default.
• W4317863179 cites W2320937221 @default.
• W4317863179 cites W2336356383 @default.
• W4317863179 cites W2470208019 @default.
• W4317863179 cites W2519603001 @default.
• W4317863179 cites W2527848138 @default.
• W4317863179 cites W2548612287 @default.
• W4317863179 cites W2570938003 @default.
• W4317863179 cites W2575639350 @default.
• W4317863179 cites W2609752905 @default.
• W4317863179 cites W2788004657 @default.
• W4317863179 cites W2792934812 @default.
• W4317863179 cites W2803368909 @default.
• W4317863179 cites W2803602511 @default.
• W4317863179 cites W2915852129 @default.
• W4317863179 cites W2921214313 @default.
• W4317863179 cites W2924081358 @default.
• W4317863179 cites W2935703421 @default.
• W4317863179 cites W3003734947 @default.
• W4317863179 cites W3022612657 @default.
• W4317863179 cites W3023668533 @default.
• W4317863179 cites W3049484804 @default.
• W4317863179 cites W3083306434 @default.
• W4317863179 cites W3097783632 @default.
• W4317863179 cites W3122734674 @default.
• W4317863179 cites W3143265745 @default.
• W4317863179 cites W3149792503 @default.
• W4317863179 cites W3179757527 @default.
• W4317863179 cites W3201540941 @default.
• W4317863179 cites W3216868459 @default.
• W4317863179 cites W4206121490 @default.
• W4317863179 cites W4225921589 @default.
• W4317863179 cites W4229025216 @default.
• W4317863179 cites W4238511849 @default.
• W4317863179 cites W4281872253 @default.
• W4317863179 doi "https://doi.org/10.14309/ajg.0000000000002146" @default.
• W4317863179 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36693030" @default.
• W4317863179 hasPublicationYear "2022" @default.
• W4317863179 type Work @default.
• W4317863179 citedByCount "2" @default.
• W4317863179 countsByYear W43178631792023 @default.
• W4317863179 crossrefType "journal-article" @default.
• W4317863179 hasAuthorship W4317863179A5013149128 @default.
• W4317863179 hasAuthorship W4317863179A5044432895 @default.
• W4317863179 hasConcept C112930515 @default.
• W4317863179 hasConcept C126322002 @default.
• W4317863179 hasConcept C143998085 @default.
• W4317863179 hasConcept C2776409635 @default.
• W4317863179 hasConcept C2776962512 @default.
• W4317863179 hasConcept C2780867798 @default.
• W4317863179 hasConcept C3019080777 @default.
• W4317863179 hasConcept C71924100 @default.
• W4317863179 hasConceptScore W4317863179C112930515 @default.
• W4317863179 hasConceptScore W4317863179C126322002 @default.
• W4317863179 hasConceptScore W4317863179C143998085 @default.
• W4317863179 hasConceptScore W4317863179C2776409635 @default.
• W4317863179 hasConceptScore W4317863179C2776962512 @default.
• W4317863179 hasConceptScore W4317863179C2780867798 @default.
• W4317863179 hasConceptScore W4317863179C3019080777 @default.
• W4317863179 hasConceptScore W4317863179C71924100 @default.
• W4317863179 hasIssue "4" @default.
• W4317863179 hasLocation W43178631791 @default.
• W4317863179 hasLocation W43178631792 @default.
• W4317863179 hasOpenAccess W4317863179 @default.
• W4317863179 hasPrimaryLocation W43178631791 @default.
• W4317863179 hasRelatedWork W129916352 @default.
• W4317863179 hasRelatedWork W1761751550 @default.
• W4317863179 hasRelatedWork W1992605662 @default.
• W4317863179 hasRelatedWork W2006667173 @default.

• next