Matches in SemOpenAlex for { <https://semopenalex.org/work/W4317884037> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W4317884037 endingPage "202" @default.
- W4317884037 startingPage "196" @default.
- W4317884037 abstract "Ashwagandha (Withania somniferous) is one of the most important plants of folk medicine and is widely used to treat various diseases. Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are defined as a respiratory failure that abruptly develops due to hypoxemia with alveolar injury secondary to intense inflammation. The present study was focused on evaluating the activity of Ashwagandha against Oleic Acid-Induced ALI/ARDS in a rat model. For this purpose, the animals were divided into the following three groups: Control, Oleic acid (50 μl kg−1, i.v. injection), Ashwagandha (500 mg/kg, orally) + Oleic acid. Ashwagandha was given daily for two weeks before a single dose of the Oleic acid. 24 hours after the last application, all the group animals were sacrificed by sevoflurane, and their lung was evaluated. The levels of Mitogen-activated protein kinases (MAPK), and the activities of myeloperoxidase (MPO), glutathione (GSH), superoxide dismutase (SOD), total oxidant status (TOS), and angiotensin-converting enzyme (ACE) were determined in lung tissues by ELISA. Compared with the model group, there was a significantly improving in the levels of MAPK, MPO, and TOS in the Ashwagandha administration group. Moreover, Ashwagandha markedly increased the activities of GSH and SOD, and decreased the activity of ACE. Therefore, Ashwagandha may be used as a potential natural resource for mitigating acute lung injury caused by Oleic acid." @default.
- W4317884037 created "2023-01-25" @default.
- W4317884037 creator A5011915819 @default.
- W4317884037 date "2023-01-28" @default.
- W4317884037 modified "2023-09-25" @default.
- W4317884037 title "Ashwagandha root extract attenuates inflammation in Oleic acid induced-ALI/ARDS rat model via inhibition of ACE and MAPK signaling pathways" @default.
- W4317884037 cites W1595363731 @default.
- W4317884037 cites W1964982019 @default.
- W4317884037 cites W1965686157 @default.
- W4317884037 cites W1983019829 @default.
- W4317884037 cites W2003029950 @default.
- W4317884037 cites W2015271346 @default.
- W4317884037 cites W2036942985 @default.
- W4317884037 cites W2038089968 @default.
- W4317884037 cites W2052865101 @default.
- W4317884037 cites W2084467463 @default.
- W4317884037 cites W2086547697 @default.
- W4317884037 cites W2119279345 @default.
- W4317884037 cites W2124743010 @default.
- W4317884037 cites W2339957855 @default.
- W4317884037 cites W2565128043 @default.
- W4317884037 cites W2782229719 @default.
- W4317884037 cites W2884639761 @default.
- W4317884037 cites W2947849452 @default.
- W4317884037 cites W2973307309 @default.
- W4317884037 cites W2987783202 @default.
- W4317884037 cites W3012619627 @default.
- W4317884037 cites W3041947393 @default.
- W4317884037 cites W3081477423 @default.
- W4317884037 cites W3089455679 @default.
- W4317884037 cites W3191510884 @default.
- W4317884037 cites W3202927745 @default.
- W4317884037 cites W3203479232 @default.
- W4317884037 cites W3214286595 @default.
- W4317884037 cites W4283034403 @default.
- W4317884037 doi "https://doi.org/10.30910/turkjans.1209593" @default.
- W4317884037 hasPublicationYear "2023" @default.
- W4317884037 type Work @default.
- W4317884037 citedByCount "0" @default.
- W4317884037 crossrefType "journal-article" @default.
- W4317884037 hasAuthorship W4317884037A5011915819 @default.
- W4317884037 hasBestOaLocation W43178840371 @default.
- W4317884037 hasConcept C126322002 @default.
- W4317884037 hasConcept C142724271 @default.
- W4317884037 hasConcept C181199279 @default.
- W4317884037 hasConcept C185592680 @default.
- W4317884037 hasConcept C203565725 @default.
- W4317884037 hasConcept C204787440 @default.
- W4317884037 hasConcept C2775838275 @default.
- W4317884037 hasConcept C2776151105 @default.
- W4317884037 hasConcept C2776348555 @default.
- W4317884037 hasConcept C2776914184 @default.
- W4317884037 hasConcept C2777714996 @default.
- W4317884037 hasConcept C2778760513 @default.
- W4317884037 hasConcept C2780069950 @default.
- W4317884037 hasConcept C2781403372 @default.
- W4317884037 hasConcept C538909803 @default.
- W4317884037 hasConcept C55493867 @default.
- W4317884037 hasConcept C71924100 @default.
- W4317884037 hasConcept C98274493 @default.
- W4317884037 hasConceptScore W4317884037C126322002 @default.
- W4317884037 hasConceptScore W4317884037C142724271 @default.
- W4317884037 hasConceptScore W4317884037C181199279 @default.
- W4317884037 hasConceptScore W4317884037C185592680 @default.
- W4317884037 hasConceptScore W4317884037C203565725 @default.
- W4317884037 hasConceptScore W4317884037C204787440 @default.
- W4317884037 hasConceptScore W4317884037C2775838275 @default.
- W4317884037 hasConceptScore W4317884037C2776151105 @default.
- W4317884037 hasConceptScore W4317884037C2776348555 @default.
- W4317884037 hasConceptScore W4317884037C2776914184 @default.
- W4317884037 hasConceptScore W4317884037C2777714996 @default.
- W4317884037 hasConceptScore W4317884037C2778760513 @default.
- W4317884037 hasConceptScore W4317884037C2780069950 @default.
- W4317884037 hasConceptScore W4317884037C2781403372 @default.
- W4317884037 hasConceptScore W4317884037C538909803 @default.
- W4317884037 hasConceptScore W4317884037C55493867 @default.
- W4317884037 hasConceptScore W4317884037C71924100 @default.
- W4317884037 hasConceptScore W4317884037C98274493 @default.
- W4317884037 hasIssue "1" @default.
- W4317884037 hasLocation W43178840371 @default.
- W4317884037 hasLocation W43178840372 @default.
- W4317884037 hasOpenAccess W4317884037 @default.
- W4317884037 hasPrimaryLocation W43178840371 @default.
- W4317884037 hasRelatedWork W1971434563 @default.
- W4317884037 hasRelatedWork W1994127376 @default.
- W4317884037 hasRelatedWork W1996172754 @default.
- W4317884037 hasRelatedWork W2027556442 @default.
- W4317884037 hasRelatedWork W2052029498 @default.
- W4317884037 hasRelatedWork W2061531262 @default.
- W4317884037 hasRelatedWork W2069810445 @default.
- W4317884037 hasRelatedWork W2375140672 @default.
- W4317884037 hasRelatedWork W3146297089 @default.
- W4317884037 hasRelatedWork W88841968 @default.
- W4317884037 hasVolume "10" @default.
- W4317884037 isParatext "false" @default.
- W4317884037 isRetracted "false" @default.
- W4317884037 workType "article" @default.