FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4317885421> ?p ?o ?g. }

• W4317885421 endingPage "863" @default.
• W4317885421 startingPage "853" @default.
• W4317885421 abstract "NT-proBNP has been hypothesized as a possible explanation for the paradoxical association between adiponectin and cardiovascular and all-cause mortality. We examined the heterogeneities by NT-proBNP, sex, BMI, smoking status, hypertension and diabetes status in the association between adiponectin and cardiovascular disease risk and mortality.We used a case-cohort design nested within the EPIC-Heidelberg cohort, including 1387 incident cases of myocardial infarction or stroke, 582 deaths from cardiovascular causes and 2352 total deaths. We estimated hazard ratios for the association between 1SD increase in log-transformed total adiponectin levels and cardiovascular disease risk, cardiovascular mortality and mortality using Prentice-weighted Cox-proportional hazard models and assessed heterogeneity of the associations across strata of covariates. Overall, adiponectin was significantly associated with all-cause mortality [HR = 1.09, 95% CI: 1.03-1.16, p = 0.004]. The association with cardiovascular mortality did not reach statistical significance [1.10 (0.99-1.37), p = 0.073]. There was significant heterogeneity by NT-proBNP in the association between total adiponectin and all-cause mortality (phet = 0.019) such that significant increase in hazards of mortality were restricted to participants in the highest tertile of NT-proBNP. Among these participants, adiponectin showed a dose-response relationship with total mortality such that; compared to participants in the lowest quintile, those in the third, fourth and fifth were at 1.22 (0.87-1.70), 1.50 (1.07-2.11), and 1.59 (1.15-2.21) higher hazards of mortality respectively.Significant association between adiponectin and mortality was only observed in the context of high NT-proBNP. Our findings provide further support for hypothesis that NT-proBNP may explain the adiponectin paradox." @default.
• W4317885421 created "2023-01-25" @default.
• W4317885421 creator A5033124357 @default.
• W4317885421 creator A5051913223 @default.
• W4317885421 creator A5071536718 @default.
• W4317885421 creator A5091448437 @default.
• W4317885421 date "2023-04-01" @default.
• W4317885421 modified "2023-09-30" @default.
• W4317885421 title "A case-cohort study of the association between adiponectin and mortality in EPIC–Heidelberg: NT-proBNP may explain the adiponectin paradox" @default.
• W4317885421 cites W155371748 @default.
• W4317885421 cites W1570155932 @default.
• W4317885421 cites W1830919232 @default.
• W4317885421 cites W1940372873 @default.
• W4317885421 cites W1967050832 @default.
• W4317885421 cites W1970435801 @default.
• W4317885421 cites W1985169250 @default.
• W4317885421 cites W1989305686 @default.
• W4317885421 cites W2005447259 @default.
• W4317885421 cites W2006261931 @default.
• W4317885421 cites W2033488250 @default.
• W4317885421 cites W2034765153 @default.
• W4317885421 cites W2065697164 @default.
• W4317885421 cites W2072526806 @default.
• W4317885421 cites W2078715111 @default.
• W4317885421 cites W2090822920 @default.
• W4317885421 cites W2094923934 @default.
• W4317885421 cites W2118981387 @default.
• W4317885421 cites W2139950016 @default.
• W4317885421 cites W2144968122 @default.
• W4317885421 cites W2167504169 @default.
• W4317885421 cites W2168553115 @default.
• W4317885421 cites W2221465226 @default.
• W4317885421 cites W2343704031 @default.
• W4317885421 cites W2413926262 @default.
• W4317885421 cites W2461096051 @default.
• W4317885421 cites W2521306464 @default.
• W4317885421 cites W2588791074 @default.
• W4317885421 cites W2610348712 @default.
• W4317885421 cites W2616009730 @default.
• W4317885421 cites W2778242679 @default.
• W4317885421 cites W2889248919 @default.
• W4317885421 cites W2899410134 @default.
• W4317885421 cites W2908611668 @default.
• W4317885421 cites W2995030404 @default.
• W4317885421 cites W3085773862 @default.
• W4317885421 cites W3126167614 @default.
• W4317885421 cites W3204593961 @default.
• W4317885421 cites W4200507436 @default.
• W4317885421 doi "https://doi.org/10.1016/j.numecd.2023.01.014" @default.
• W4317885421 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36740561" @default.
• W4317885421 hasPublicationYear "2023" @default.
• W4317885421 type Work @default.
• W4317885421 citedByCount "2" @default.
• W4317885421 countsByYear W43178854212023 @default.
• W4317885421 crossrefType "journal-article" @default.
• W4317885421 hasAuthorship W4317885421A5033124357 @default.
• W4317885421 hasAuthorship W4317885421A5051913223 @default.
• W4317885421 hasAuthorship W4317885421A5071536718 @default.
• W4317885421 hasAuthorship W4317885421A5091448437 @default.
• W4317885421 hasBestOaLocation W43178854211 @default.
• W4317885421 hasConcept C126322002 @default.
• W4317885421 hasConcept C134018914 @default.
• W4317885421 hasConcept C201903717 @default.
• W4317885421 hasConcept C207103383 @default.
• W4317885421 hasConcept C2776782570 @default.
• W4317885421 hasConcept C2777391703 @default.
• W4317885421 hasConcept C44249647 @default.
• W4317885421 hasConcept C500558357 @default.
• W4317885421 hasConcept C50382708 @default.
• W4317885421 hasConcept C511355011 @default.
• W4317885421 hasConcept C555293320 @default.
• W4317885421 hasConcept C71924100 @default.
• W4317885421 hasConcept C72563966 @default.
• W4317885421 hasConceptScore W4317885421C126322002 @default.
• W4317885421 hasConceptScore W4317885421C134018914 @default.
• W4317885421 hasConceptScore W4317885421C201903717 @default.
• W4317885421 hasConceptScore W4317885421C207103383 @default.
• W4317885421 hasConceptScore W4317885421C2776782570 @default.
• W4317885421 hasConceptScore W4317885421C2777391703 @default.
• W4317885421 hasConceptScore W4317885421C44249647 @default.
• W4317885421 hasConceptScore W4317885421C500558357 @default.
• W4317885421 hasConceptScore W4317885421C50382708 @default.
• W4317885421 hasConceptScore W4317885421C511355011 @default.
• W4317885421 hasConceptScore W4317885421C555293320 @default.
• W4317885421 hasConceptScore W4317885421C71924100 @default.
• W4317885421 hasConceptScore W4317885421C72563966 @default.
• W4317885421 hasIssue "4" @default.
• W4317885421 hasLocation W43178854211 @default.
• W4317885421 hasLocation W43178854212 @default.
• W4317885421 hasOpenAccess W4317885421 @default.
• W4317885421 hasPrimaryLocation W43178854211 @default.
• W4317885421 hasRelatedWork W1971184210 @default.
• W4317885421 hasRelatedWork W2076222267 @default.
• W4317885421 hasRelatedWork W2088840838 @default.
• W4317885421 hasRelatedWork W2115405528 @default.
• W4317885421 hasRelatedWork W2569135542 @default.
• W4317885421 hasRelatedWork W3084364512 @default.
• W4317885421 hasRelatedWork W3108721673 @default.

• next