Matches in SemOpenAlex for { <https://semopenalex.org/work/W4317894200> ?p ?o ?g. }
- W4317894200 endingPage "1392" @default.
- W4317894200 startingPage "1377" @default.
- W4317894200 abstract "Abstract Marine red algae have been known as an excellent source for natural sunscreens and antioxidants for a long time, which outlines their potential for various medical and cosmeceutical applications. This is due to their synthesis of unique secondary metabolites to shield themselves from high levels of UV-A and -B radiation encountered in their natural habitats. In this study, a comprehensive and contemporary way for the detection, visualization, and dereplication of algal natural products with special focus on mycosporine-like amino acids (MAAs) is shown, employing HR-MS/MS metabolomics. 33 crude algal extracts were explored using ultra-high-performance liquid chromatography (UHPLC) hyphenated to orbitrap high-resolution tandem mass spectroscopy (HRMS 2 ). Acquired raw data, subjected to pretreatment and spectral organization, could subsequently be implemented in the Global Natural Products Social (GNPS) workflow, whereby a feature based molecular network (FBMN) was created and visualized in Cytoscape. This FBMN was matched against an in-house as well as open source library on the GNPS platform and additionally enhanced by chemotaxonomic classification software and spectra of standard MAAs, as well as further information layers covering e.g. physicochemical properties, taxonomy, and fragmentation behavior. Based on the integration of the latest in silico annotation tools (SIRIUS, CANOPUS, MSNovelist) as well as already published fragmentation patterns of MAAs, structures for known compounds could be corroborated as well as those for novel substances proposed. This offers an interesting and state-of-the-art approach towards the identification and classification of known and new MAAs." @default.
- W4317894200 created "2023-01-25" @default.
- W4317894200 creator A5008522457 @default.
- W4317894200 creator A5028595304 @default.
- W4317894200 creator A5033557135 @default.
- W4317894200 creator A5070592083 @default.
- W4317894200 date "2023-01-24" @default.
- W4317894200 modified "2023-10-14" @default.
- W4317894200 title "Application of feature-based molecular networking in the field of algal research with special focus on mycosporine-like amino acids" @default.
- W4317894200 cites W1913121021 @default.
- W4317894200 cites W1983316767 @default.
- W4317894200 cites W1989299822 @default.
- W4317894200 cites W2010281075 @default.
- W4317894200 cites W2020869810 @default.
- W4317894200 cites W2036901056 @default.
- W4317894200 cites W2050057037 @default.
- W4317894200 cites W2059327215 @default.
- W4317894200 cites W2081465448 @default.
- W4317894200 cites W2087431799 @default.
- W4317894200 cites W2102561373 @default.
- W4317894200 cites W2159675211 @default.
- W4317894200 cites W2179948434 @default.
- W4317894200 cites W2504691963 @default.
- W4317894200 cites W2548357532 @default.
- W4317894200 cites W2555163954 @default.
- W4317894200 cites W2584520879 @default.
- W4317894200 cites W2606155904 @default.
- W4317894200 cites W2618895543 @default.
- W4317894200 cites W2793598048 @default.
- W4317894200 cites W2806146607 @default.
- W4317894200 cites W2902472794 @default.
- W4317894200 cites W2904596821 @default.
- W4317894200 cites W2922522932 @default.
- W4317894200 cites W2941238267 @default.
- W4317894200 cites W2952560581 @default.
- W4317894200 cites W2956419562 @default.
- W4317894200 cites W2997217863 @default.
- W4317894200 cites W3025883815 @default.
- W4317894200 cites W3034348464 @default.
- W4317894200 cites W3043137093 @default.
- W4317894200 cites W3080362420 @default.
- W4317894200 cites W3080789666 @default.
- W4317894200 cites W3090257159 @default.
- W4317894200 cites W3106737077 @default.
- W4317894200 cites W3120127067 @default.
- W4317894200 cites W3125932154 @default.
- W4317894200 cites W3157730299 @default.
- W4317894200 cites W3164474332 @default.
- W4317894200 cites W3215966386 @default.
- W4317894200 cites W3216857338 @default.
- W4317894200 cites W4206232119 @default.
- W4317894200 cites W4210322610 @default.
- W4317894200 cites W4210657158 @default.
- W4317894200 cites W4214886240 @default.
- W4317894200 cites W4223990414 @default.
- W4317894200 cites W4238497413 @default.
- W4317894200 cites W4281688302 @default.
- W4317894200 cites W4282979137 @default.
- W4317894200 doi "https://doi.org/10.1007/s10811-023-02906-3" @default.
- W4317894200 hasPublicationYear "2023" @default.
- W4317894200 type Work @default.
- W4317894200 citedByCount "0" @default.
- W4317894200 crossrefType "journal-article" @default.
- W4317894200 hasAuthorship W4317894200A5008522457 @default.
- W4317894200 hasAuthorship W4317894200A5028595304 @default.
- W4317894200 hasAuthorship W4317894200A5033557135 @default.
- W4317894200 hasAuthorship W4317894200A5070592083 @default.
- W4317894200 hasBestOaLocation W43178942001 @default.
- W4317894200 hasConcept C162356407 @default.
- W4317894200 hasConcept C177212765 @default.
- W4317894200 hasConcept C185592680 @default.
- W4317894200 hasConcept C21565614 @default.
- W4317894200 hasConcept C2780841973 @default.
- W4317894200 hasConcept C41008148 @default.
- W4317894200 hasConcept C43617362 @default.
- W4317894200 hasConcept C60644358 @default.
- W4317894200 hasConcept C68762167 @default.
- W4317894200 hasConcept C70721500 @default.
- W4317894200 hasConcept C77088390 @default.
- W4317894200 hasConcept C86803240 @default.
- W4317894200 hasConceptScore W4317894200C162356407 @default.
- W4317894200 hasConceptScore W4317894200C177212765 @default.
- W4317894200 hasConceptScore W4317894200C185592680 @default.
- W4317894200 hasConceptScore W4317894200C21565614 @default.
- W4317894200 hasConceptScore W4317894200C2780841973 @default.
- W4317894200 hasConceptScore W4317894200C41008148 @default.
- W4317894200 hasConceptScore W4317894200C43617362 @default.
- W4317894200 hasConceptScore W4317894200C60644358 @default.
- W4317894200 hasConceptScore W4317894200C68762167 @default.
- W4317894200 hasConceptScore W4317894200C70721500 @default.
- W4317894200 hasConceptScore W4317894200C77088390 @default.
- W4317894200 hasConceptScore W4317894200C86803240 @default.
- W4317894200 hasIssue "3" @default.
- W4317894200 hasLocation W43178942001 @default.
- W4317894200 hasOpenAccess W4317894200 @default.
- W4317894200 hasPrimaryLocation W43178942001 @default.
- W4317894200 hasRelatedWork W1972763168 @default.
- W4317894200 hasRelatedWork W2044091012 @default.