Matches in SemOpenAlex for { <https://semopenalex.org/work/W4317938182> ?p ?o ?g. }
- W4317938182 abstract "The dried flower bud of Syzygium aromaticum L. (S. aromaticum) (Myrtaceae), cloves, have been used for their analgesic and anti-inflammatory activities. Peritoneal adhesion (PA) is the most common complication of abdominal and pelvic surgeries, which causes significant adverse effects and severe economic burden. The present study aimed to evaluate the preventive effect of S. extract (SAE) on PA formation in a rat model. Male Wistar 8-week-old rats were randomly divided into sham, control (received vehicle), and treatment (0.25%, 0.5%, and 1% w/v of SAE) groups. The adhesion and related factors were examined using the Nair scoring system and immunological and biochemical kits for the levels of inflammatory cytokines [interleukin (IL)-6 and tumor necrosis factor (TNF)-α], growth factors [transforming growth factor (TGF)-β1 and vascular endothelial growth factor (VEGF)], oxidative [nitric oxide (NO) and malondialdehyde (MDA)], and anti-oxidative [glutathione (GSH)] factors. Our results figured out that the adhesion score and IL-6, TNF-α, TGF-β1, VEGF, NO, and MDA levels were significantly increased, but the GSH level was decreased in the control group compared to the sham group (p < 0.001-0.05). On the other hand, the 0.25% SAE group had a lower adhesion score, and IL-6, TNF-α, TGF-β1, VEGF, NO, and MDA levels were significantly decreased compared with the vehicle group, and the level of GSH was increased (p < 0.001-0.05). SAE could efficiently reduce adhesion score and regulate inflammatory cytokines, oxidative and anti-oxidative factors, and biomarkers of fibrosis and angiogenesis. Therefore, clove extract can be considered a potential candidate for PA management." @default.
- W4317938182 created "2023-01-25" @default.
- W4317938182 creator A5003021261 @default.
- W4317938182 creator A5017311650 @default.
- W4317938182 creator A5021736632 @default.
- W4317938182 creator A5026279149 @default.
- W4317938182 creator A5032595344 @default.
- W4317938182 creator A5041437083 @default.
- W4317938182 creator A5052254868 @default.
- W4317938182 date "2023-01-01" @default.
- W4317938182 modified "2023-10-12" @default.
- W4317938182 title "<scp>HPLC</scp>/<scp>MS</scp> characterization of <i>Syzygium aromaticum</i> L. and evaluation of its effects on peritoneal adhesion: Investigating the role of inflammatory cytokines, oxidative factors, and fibrosis and angiogenesis biomarkers" @default.
- W4317938182 cites W1489693778 @default.
- W4317938182 cites W1966828849 @default.
- W4317938182 cites W1974283290 @default.
- W4317938182 cites W1975425771 @default.
- W4317938182 cites W1975812543 @default.
- W4317938182 cites W1976454560 @default.
- W4317938182 cites W1978288927 @default.
- W4317938182 cites W1999258196 @default.
- W4317938182 cites W2002197859 @default.
- W4317938182 cites W2004526768 @default.
- W4317938182 cites W2007688256 @default.
- W4317938182 cites W2013821934 @default.
- W4317938182 cites W2017658910 @default.
- W4317938182 cites W2026687368 @default.
- W4317938182 cites W2028453113 @default.
- W4317938182 cites W2029884920 @default.
- W4317938182 cites W2047023779 @default.
- W4317938182 cites W2050206789 @default.
- W4317938182 cites W2061370229 @default.
- W4317938182 cites W2066114225 @default.
- W4317938182 cites W2066689262 @default.
- W4317938182 cites W2088481577 @default.
- W4317938182 cites W2092452665 @default.
- W4317938182 cites W2097056441 @default.
- W4317938182 cites W2097382995 @default.
- W4317938182 cites W2098381099 @default.
- W4317938182 cites W2103538496 @default.
- W4317938182 cites W2107742423 @default.
- W4317938182 cites W2108158948 @default.
- W4317938182 cites W2110582342 @default.
- W4317938182 cites W2111646294 @default.
- W4317938182 cites W2115356077 @default.
- W4317938182 cites W2115467203 @default.
- W4317938182 cites W2120274577 @default.
- W4317938182 cites W2124664765 @default.
- W4317938182 cites W2129324235 @default.
- W4317938182 cites W2129453836 @default.
- W4317938182 cites W2146600383 @default.
- W4317938182 cites W2149116298 @default.
- W4317938182 cites W2152026308 @default.
- W4317938182 cites W2156746712 @default.
- W4317938182 cites W2171127905 @default.
- W4317938182 cites W2177726270 @default.
- W4317938182 cites W2224708429 @default.
- W4317938182 cites W2324806325 @default.
- W4317938182 cites W2328115092 @default.
- W4317938182 cites W2332682914 @default.
- W4317938182 cites W2621938032 @default.
- W4317938182 cites W2741375525 @default.
- W4317938182 cites W2746022576 @default.
- W4317938182 cites W2789744985 @default.
- W4317938182 cites W2895089732 @default.
- W4317938182 cites W2896543562 @default.
- W4317938182 cites W2903183055 @default.
- W4317938182 cites W2906720077 @default.
- W4317938182 cites W2985753878 @default.
- W4317938182 cites W2992095079 @default.
- W4317938182 cites W3007650473 @default.
- W4317938182 cites W3163472963 @default.
- W4317938182 cites W3193192169 @default.
- W4317938182 cites W3199059034 @default.
- W4317938182 cites W4200213841 @default.
- W4317938182 cites W4235333461 @default.
- W4317938182 cites W4317938182 @default.
- W4317938182 cites W977718583 @default.
- W4317938182 doi "https://doi.org/10.14814/phy2.15584" @default.
- W4317938182 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36695659" @default.
- W4317938182 hasPublicationYear "2023" @default.
- W4317938182 type Work @default.
- W4317938182 citedByCount "1" @default.
- W4317938182 countsByYear W43179381822023 @default.
- W4317938182 crossrefType "journal-article" @default.
- W4317938182 hasAuthorship W4317938182A5003021261 @default.
- W4317938182 hasAuthorship W4317938182A5017311650 @default.
- W4317938182 hasAuthorship W4317938182A5021736632 @default.
- W4317938182 hasAuthorship W4317938182A5026279149 @default.
- W4317938182 hasAuthorship W4317938182A5032595344 @default.
- W4317938182 hasAuthorship W4317938182A5041437083 @default.
- W4317938182 hasAuthorship W4317938182A5052254868 @default.
- W4317938182 hasBestOaLocation W43179381821 @default.
- W4317938182 hasConcept C126322002 @default.
- W4317938182 hasConcept C164027704 @default.
- W4317938182 hasConcept C167734588 @default.
- W4317938182 hasConcept C178790620 @default.
- W4317938182 hasConcept C17991360 @default.
- W4317938182 hasConcept C181199279 @default.
- W4317938182 hasConcept C185592680 @default.
- W4317938182 hasConcept C203014093 @default.