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- W4318019016 abstract "Lignin and chitosan are natural polymers that exhibit antioxidant and wound-healing properties, respectively. In this study, lignin-chitosan polymeric films were prepared using solvent-casting method. Physicochemical characterization of prepared films was carried out using FESEM, FTIR and DSC. An antibiotic neomycin sulphate was loaded onto films and drug-release profile, antioxidant activity, hemolytic activity, cell viability and antimicrobial activity of film were evaluated. The films were observed to be smooth and have uniform surface with homogenous and fibrous nature. The cumulative release of 97.94% in 8 h was observed in drug release study and it followed Weibull_4 order release kinetics. The film was non-hemolytic and exhibited excellent antioxidant activity with no toxicity towards fibroblast cells. Additionally, the drug-loaded film showed significant antimicrobial activity against both Gram-negative and Gram-positive bacteria." @default.
- W4318019016 created "2023-01-26" @default.
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- W4318019016 date "2023-04-01" @default.
- W4318019016 modified "2023-10-16" @default.
- W4318019016 title "Lignin-chitosan biocomposite film for antimicrobial activity: Fabrication, characterization and in-vitro evaluation" @default.
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- W4318019016 doi "https://doi.org/10.1016/j.matlet.2023.133956" @default.
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