FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4318204427> ?p ?o ?g. }

• W4318204427 endingPage "318" @default.
• W4318204427 startingPage "318" @default.
• W4318204427 abstract "Fabrication of micro- and nanofibers are critical for a wide range of applications from microelectronics to biotechnology. Alginate microfibers with diameters of tens to hundreds of microns play an important role in tissue engineering and fibers of these diameters are impossible to fabricate via electrospinning and can only be produced via fluidic spinning. Typically, microfluidic spinning based on photopolymerization produces fibers that are not easily dissolvable, while fluidic spinning with chemical cross-linking employs complex setups of microfabricated chips or coaxial needles, aimed at precise control of the fiber diameter; however, fluidic spinning introduces significant cost and complexity to the microfluidic setup. We demonstrate immersed microfluidic spinning where a calcium alginate microfiber is produced via displacement of alginate solution through a single needle that is immersed in a cross-linking bath of calcium chloride solution. The resulting diameter of the fiber is characterized and the fiber diameter and topology of the deposited fiber is related to the concentration of the alginate solution (2 wt%, 4 wt%, and 6 wt%), needle gauge (30 g, 25 g, and 20 g), and the volumetric flow rate of the alginate solution (1 mL/min, 2 mL/min, and 2.7 mL/min). The resulting fiber diameter is smaller than the internal diameter of the needle and this dependence is explained by the continuity of the flow and increased rate of fall of the liquid jet upon its issuing from the needle. The fiber diameter (demonstrated diameter of fibers range from 100 microns to 1 mm) depends weakly on the volumetric flow rate and depends strongly on the needle diameter. It also seems that for a smaller needle size, a greater concentration of alginate results in smaller diameter fibers and that this trend is not evident as the needle diameter is increased. In terms of topology of the deposited fiber, the higher wt% alginate fiber produces larger loops, while smaller wt% alginate solution yields a denser topology of the overlaid fiber loops. These fibers can be dissolved in DMEM/EDTA/DSC solution in 20–30 min (depending on the fiber diameter), leaving behind the hollow channels in the hydrogel matrix. We believe that the demonstrated simple setup of the immersed microfluidic spinning of the calcium alginate microfibers will be useful for creating tissue constructs, including the vascularized tissue implants." @default.
• W4318204427 created "2023-01-27" @default.
• W4318204427 creator A5006942986 @default.
• W4318204427 creator A5028247832 @default.
• W4318204427 creator A5089627053 @default.
• W4318204427 creator A5091518967 @default.
• W4318204427 date "2023-01-26" @default.
• W4318204427 modified "2023-09-26" @default.
• W4318204427 title "Dissolvable Calcium Alginate Microfibers Produced via Immersed Microfluidic Spinning" @default.
• W4318204427 cites W1972570419 @default.
• W4318204427 cites W2020646311 @default.
• W4318204427 cites W2079184484 @default.
• W4318204427 cites W2529142035 @default.
• W4318204427 cites W2547262795 @default.
• W4318204427 cites W2769837588 @default.
• W4318204427 cites W2791409904 @default.
• W4318204427 cites W2945398328 @default.
• W4318204427 cites W2947937693 @default.
• W4318204427 cites W2991023973 @default.
• W4318204427 cites W3041853375 @default.
• W4318204427 cites W3137012322 @default.
• W4318204427 cites W3213116490 @default.
• W4318204427 cites W4210350220 @default.
• W4318204427 cites W4290755567 @default.
• W4318204427 doi "https://doi.org/10.3390/mi14020318" @default.
• W4318204427 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36838018" @default.
• W4318204427 hasPublicationYear "2023" @default.
• W4318204427 type Work @default.
• W4318204427 citedByCount "1" @default.
• W4318204427 countsByYear W43182044272023 @default.
• W4318204427 crossrefType "journal-article" @default.
• W4318204427 hasAuthorship W4318204427A5006942986 @default.
• W4318204427 hasAuthorship W4318204427A5028247832 @default.
• W4318204427 hasAuthorship W4318204427A5089627053 @default.
• W4318204427 hasAuthorship W4318204427A5091518967 @default.
• W4318204427 hasBestOaLocation W43182044271 @default.
• W4318204427 hasConcept C119599485 @default.
• W4318204427 hasConcept C121332964 @default.
• W4318204427 hasConcept C127413603 @default.
• W4318204427 hasConcept C12820456 @default.
• W4318204427 hasConcept C132651336 @default.
• W4318204427 hasConcept C136229726 @default.
• W4318204427 hasConcept C136525101 @default.
• W4318204427 hasConcept C142724271 @default.
• W4318204427 hasConcept C144796933 @default.
• W4318204427 hasConcept C146978453 @default.
• W4318204427 hasConcept C154815118 @default.
• W4318204427 hasConcept C159985019 @default.
• W4318204427 hasConcept C171250308 @default.
• W4318204427 hasConcept C172120300 @default.
• W4318204427 hasConcept C187937830 @default.
• W4318204427 hasConcept C191897082 @default.
• W4318204427 hasConcept C192562407 @default.
• W4318204427 hasConcept C204787440 @default.
• W4318204427 hasConcept C2778713300 @default.
• W4318204427 hasConcept C51221625 @default.
• W4318204427 hasConcept C519063684 @default.
• W4318204427 hasConcept C519885992 @default.
• W4318204427 hasConcept C521977710 @default.
• W4318204427 hasConcept C62520636 @default.
• W4318204427 hasConcept C71924100 @default.
• W4318204427 hasConcept C8673954 @default.
• W4318204427 hasConcept C91129048 @default.
• W4318204427 hasConceptScore W4318204427C119599485 @default.
• W4318204427 hasConceptScore W4318204427C121332964 @default.
• W4318204427 hasConceptScore W4318204427C127413603 @default.
• W4318204427 hasConceptScore W4318204427C12820456 @default.
• W4318204427 hasConceptScore W4318204427C132651336 @default.
• W4318204427 hasConceptScore W4318204427C136229726 @default.
• W4318204427 hasConceptScore W4318204427C136525101 @default.
• W4318204427 hasConceptScore W4318204427C142724271 @default.
• W4318204427 hasConceptScore W4318204427C144796933 @default.
• W4318204427 hasConceptScore W4318204427C146978453 @default.
• W4318204427 hasConceptScore W4318204427C154815118 @default.
• W4318204427 hasConceptScore W4318204427C159985019 @default.
• W4318204427 hasConceptScore W4318204427C171250308 @default.
• W4318204427 hasConceptScore W4318204427C172120300 @default.
• W4318204427 hasConceptScore W4318204427C187937830 @default.
• W4318204427 hasConceptScore W4318204427C191897082 @default.
• W4318204427 hasConceptScore W4318204427C192562407 @default.
• W4318204427 hasConceptScore W4318204427C204787440 @default.
• W4318204427 hasConceptScore W4318204427C2778713300 @default.
• W4318204427 hasConceptScore W4318204427C51221625 @default.
• W4318204427 hasConceptScore W4318204427C519063684 @default.
• W4318204427 hasConceptScore W4318204427C519885992 @default.
• W4318204427 hasConceptScore W4318204427C521977710 @default.
• W4318204427 hasConceptScore W4318204427C62520636 @default.
• W4318204427 hasConceptScore W4318204427C71924100 @default.
• W4318204427 hasConceptScore W4318204427C8673954 @default.
• W4318204427 hasConceptScore W4318204427C91129048 @default.
• W4318204427 hasIssue "2" @default.
• W4318204427 hasLocation W43182044271 @default.
• W4318204427 hasLocation W43182044272 @default.
• W4318204427 hasLocation W43182044273 @default.
• W4318204427 hasOpenAccess W4318204427 @default.
• W4318204427 hasPrimaryLocation W43182044271 @default.
• W4318204427 hasRelatedWork W2034002779 @default.
• W4318204427 hasRelatedWork W2034273772 @default.

• next